Effect of Inhaled Medication and Inhalation Technique on Dental Caries in Asthmatic Patients
Open accessAbstract
BACKGROUND: The purpose of this study was to examine the relationship between the type of inhaled medication, length of use, dosing, the inhaler use technique and the severity and duration of disease on the dental caries of asthmatic patients. OBJECTIVES: In the present study, the frequency of dental caries in the asthmatic patients and control group was examined. In addition the possible association of dental caries with disease duration, disease severity, asthma symptoms, chest wheeze, PFT values, and dose of medication and inhalation use technique was evaluated. MATERIALS AND METHODS: 40 asthmatic patients of both sex (20-30 years old) and 40 age and sex matched controls were studied. In asthmatic patients, the type, dose, duration of medications, the technique of inhaler use and severity and duration of the disease were recorded. The dental health status including DT, MT, FT and DMFT (decay, missing, filling teeth) were examined. In addition, pulmonary function tests (PFTs) were performed for both groups. RESULTS: All PFT variables in asthmatic patients were significantly lower than those of control group except for FVC (P < 0.001 for all cases). All indices of dental caries in asthmatic group were higher than those of controls which was statistically significant for MT and DMFT (P < 0.005 for both cases). Only FT and DMFT in patients with 11-15 years asthma duration were significantly more than those of 6-10 years (P < 0.05 for both cases). There was no significant correlation between indices of dental caries and disease duration, PFT values; doses of medication or the technique of inhaler use; although the technique of inhaler use was relatively acceptable in all asthmatic patients. CONCLUSIONS: These results showed that dental caries among asthmatic patients was more common than control group which can be due to using inhaler drugs or the technique of inhaler use.
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Anti-asthmatic drugs have considerable effects on salivary components and properties, especially buffering capacity, quantity, and viscosity.
“In addition, drugs have considerable effects on salivary components and properties, especially in terms of the buffering capacity, quantity, and viscosity.”
From Drugs Prescribed for Asthma and Their Adverse Effects on Dental Health (2023) · cites this paper as [43]
The Background (page unavailable) says prolonged inhaler use reduces salivary flow and pH, and that β2-agonists affect saliva composition. It does not address buffering capacity or viscosity specifically, so the full list of salivary properties is not supported. (LLM, conf=0.86)
Experimental — accuracy not yet measuredAny factor that reduces the quantity and quality of saliva can negatively affect oral health because saliva plays an important role in its preservation.
“It is considered that any factor that reduces the quantity and quality of saliva can negatively affect oral health, because saliva plays a very important role in its preservation [37,43].”
From Drugs Prescribed for Asthma and Their Adverse Effects on Dental Health (2023) · cites this paper as [43]
The Background (page unavailable) links reduced salivary flow and pH from prolonged inhaler use to increased dental-caries risk, and mentions effects of medication on saliva composition. This supports the claim's underlying point, but the paper discusses inhaler medication in asthmatic patients, not any factor that changes saliva or oral health generally. (LLM, conf=0.82)
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Research works printed but not linked: 19
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Cited by
Sorted by citations
Drugs Prescribed for Asthma and Their Adverse Effects on Dental Health
Pacheco-Quito, E.-M., Jaramillo, J., Sarmiento-Ordoñez, J., & Cuenca-León, K. (2023) · Dentistry Journal · doi:10.3390/dj11050113 · Cited by 33 · see citing works
Impact of Inhalation Therapy on the Incidence of Carious Lesions in Patients with Asthma and COPD
Bozejac, B. V., Stojšin, I., Ðuric, M., Zvezdin, B., Brkanić, T., Budišin, E., Vukoje, K., & Sečen, N. (2017) · Journal of Applied Oral Science · doi:10.1590/1678-7757-2016-0147 · Cited by 35 · see citing works
- Authors
- Boskabady, M., Nematollahi, H., & Boskabady, M. H.
- Affiliations
- Mashhad University of Medical Sciences (IR)
- Corresponding author
- Boskabady, Mohammad Hossein
- Venue
- Iranian Red Crescent Medical Journal
- Publisher
- DoNotEdit
- Published
- 2012-12-06
- Volume
- 14
- Issue
- 12
- Pages
- 816-21
- ISSN
- 2074-1804 (ISSN-L)
- 2074-1812
- PMC
- PMC3587873
- OpenAlex
- W2136566327
- Cited by
- 26
- References
- 0
- Citations by year
- 2026: 1 · 2024: 3 · 2023: 3 · 2022: 1 · 2021: 1 · 2020: 4 · 2019: 3 · 2018: 3 · 2017: 2 · 2016: 2 · 2014: 3
- FWCI
- 1.16
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- cc-by
- Locations
- Iranian Red Crescent Medical Journal (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Dentistry › Periodontics › Dental Health and Care Utilization
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Keywords
- dental caries, asthma, inhaled corticosteroids, inhaler technique, DMFT index, disease duration, lung function, young adults
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