Arsenic: exposure and health effects

Abstract

The value of research on health effects of ingested inorganic arsenic. Human oral exposure to inorganic arsenic. Nationwide and California arsenic occurrence studies. Dietary intake and hazards of arsenic. Determination of total arsenic and arsenic compounds in drinking water. Sources and pathways of arsenic in Southwest England: health implications. Exposure assessment for arsenic concentrations from electric power stations. Ischemic heart disease induced by ingested inorganic arsenic. Urinary excretion of arsenic species in a human population chronically exposed to arsenic via drinking water: a pilot study. Long-term follow-up of patients treated with medicinal arsenic. Epidemiological study designs to address potential high bladder cancer risks from arsenic in drinking water. Arsenic in drinking water and urinary cancers. Arsenic in drinking water and cancers: a brief descriptive review of Taiwan studies. Review of health assessments for US/Canada populations exposed to arsenic in drinking water. Assessment of the dose response for internal cancers and arsenic in drinking water in the blackfoot disease endemic region of Taiwan. Species differences in the metabolism of arsenic. Inorganic arsenic metabolism in humans. Genotoxicity of arsenic and its methylated metabolites. Arsenic essentiality studies and factors affecting its importance. A physiologically based pharmacokinetic model for ingested arsenic. Overview of a physiologically based pharmacokinetic model for the four major arsenic species in mammals. Water utility regulatory and research projects on arsenic. The use of site-specific studies to assess arsenic health risk at superfund site. The process for setting drinking water regulations under the Safe Drinking Water Act. Arsenic in the Canadian general environment: evaluation of risks to health. Impacts of a stringent arsenic drinking water regulation on the western USA. Arsenic in drinking water: health effects and regulatory issues in California. Regulating arsenic in Nevada drinking water supplies: past problems, future challenges. The water utility perspective on arsenic regulation. Derivation of the inorganic arsenic reference dose. Arsenic and human health: some persisting scientific issues.