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Phytochemical study of Harpullia Arborea leaves
Abstract
From the leaves of Harpullia arborea (Sapindaceae), a new triterpenoid, 3beta-eicosanoyl-6beta-hydroxy-21alphaH-24-norhopa-4(23),22(29)-diene, together with a lupane-type triterpenoid, lupeol; a sterol, alpha-spinasterol and an inositol derivative, quebrachitol, has been isolated. The structure elucidation of these compounds were accomplished through the analysis of their MS, IR, [superscript 1]H-NMR and [superscript 13]C-NMR, especially the 1D-NMR and 2D-NMR data as well as comparison with reported values. In the investigation of the effects on in vitro lymphocyte proliferation of extracts from the plant and the isolated compound quebrachitol, methanol extract and quebrachitol have been found to exhibited stimulatory effect on lymphocyte proliferation.
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“Members of the genus Harpullia are known to be rich sources of saponins, triterpenes, tannins, flavonoids, and sterols [29,30,31,32,33,34].”
From Novel Green Biosynthesis of 5-Fluorouracil Chromium Nanoparticles Using Harpullia pendula Extract for Treatment of Colorectal Cancer (2021) · cites this paper as [30]
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Saddik, M. S., Elsayed, M. M. A., Abdelkader, M. S. A., El-Mokhtar, M. A., Abdel-Aleem, J. A., Abu-Dief, A. M., Al-Hakkani, M. F., Farghaly, H. S., & Abou-Taleb, H. A. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13020226 · Cited by 89
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- Poovapatthanachart, R.
- Published
- 2025
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- 0
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