HbA 1c Performance in African Descent Populations in the United States With Normal Glucose Tolerance, Prediabetes, or Diabetes: A Scoping Review
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INTRODUCTION: performance to assess glycemic status among African American, Afro-Caribbean, and African people. METHODS: results were compared with other ethnic groups or validated against the oral glucose tolerance test (OGTT), fasting plasma glucose (FPG), or previous diagnosis. We classified study results by the risk of false positives and risk of false negatives in assessing glycemic status. RESULTS: of 6.5% or higher leads to underdiagnosis. CONCLUSION: cutoffs or other test strategies that account for risk profiles unique to African American, Afro-Caribbean, and African people living in the United States.
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A recent report in Afro-Caribbean individuals found lower A1C relative to glucose values.
“In contrast, a recent report in Afro-Caribbean individuals found lower A1C relative to glucose values (17).”
From 6. Glycemic Targets: <i>Standards of Care in Diabetes—2023</i> (2023) · cites this paper as [17]
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References 57 · Cited by 40
Research works printed but not linked: 1
- [16]Chung ST, Sumner AE. Diabetes: T2DM risk prediction in populations of African descent. Nat Rev Endocrinol 2016; 12(3): 131– 2. 10.1038/nrendo.2016.2 26794440 · DOI
- Authors
- Khosla, L., Bhat, S., Fullington, L. A., & Horlyck-Romanovsky, M. F.
- Affiliations
- City University of New York (US)
- Corresponding author
- Khosla, Lakshay
- Venue
- Preventing Chronic Disease
- Published
- 2021-03-11
- Volume
- 18
- Pages
- E22-E22
- ISSN
- 1545-1151 (ISSN-L)
- PMC
- PMC7986971
- OpenAlex
- W3133752480
- Cited by
- 40
- References
- 57
- Citations by year
- 2026: 7 · 2025: 4 · 2024: 13 · 2023: 8 · 2022: 4 · 2021: 4
- FWCI
- 1.11
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- public-domain
- Locations
- Preventing Chronic Disease (publishedVersion, public-domain)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- CUNY Academic Works (City University of New York) (submittedVersion, public-domain)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Keywords
- HbA1c, glycemic status, African American population, Afro-Caribbean population, African populations, prediabetes, diabetes mellitus, normal glucose tolerance, underdiagnosis, false positives, false-negative results, oral glucose tolerance test, fasting blood glucose
- MeSH terms
- Blood Glucose, Diabetes Mellitus, Type 2, Glucose, Glycated Hemoglobin, Humans, Prediabetic State, United States
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