Cited by 4Circadian rhythm and melatoninThermoregulation and physiological responsesDiabetes Management and Research

Peripheral body temperature impairment in individuals with type 1 diabetes mellitus

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Barone, Mark Thomaz Ugliara, Gonçalves, Bruno, Menna-Barreto, Luiz·2018·Sleep Science

Abstract

Objective: The aim of the present study was to evaluate the peripheral temperature rhythmicity and control in individuals with type 1 diabetes mellitus. Methods: Twelve non-obese adults (20-40 years old) with type 1 diabetes mellitus (T1D) and eight control individuals, matched for age and BMI, wore a wrist temperature recorder for 10 consecutive days. Recorded data were aggregated to calculate M10 (ten hours of highest temperature) and L5 (five hours of lowest temperature) of wrist temperature values for both groups. Results: Mean wrist temperature and M10 were not different when comparing the groups. The wrist temperature amplitude was reduced in the T1D group (p=0.039), due to a higher L5 (p=0.038). Discussion: While the higher L5 observed in T1D could be explained by less efficient heat dissipation, the amplitude flattening coincides with that observed in elderly.

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  • The ensuing peripheral vascular disease and neuropathy impair thermoregulation specifically at night.

    “The ensuing peripheral vascular disease and neuropathy impair thermoregulation specifically at night32,33.”
  • An explanation for some of the strong associations observed in this study might be that small amplitude temperature rhythms diminish thermosensitive gene regulation, which in combination with disease-specific perturbations, like those observed for diabetic neuropathy, lead to the emergence of specific disease phenotypes.

    “An explanation for some of the strong associations observed in this study might be that small amplitude temperature rhythms diminish thermosensitive gene regulation, which in combination with disease-specific perturbations, like those observed for diabetic neuropathy,32,33 lead to the emergence of specific disease phenotypes.”

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References 19 · Cited by 4

Research works printed but not linked: 1

  1. [8]Colwell CS Circadian Medicine New York Wiley-Blackwell 2015

Authors
Barone, M. T. U., Gonçalves, B., & Menna-Barreto, L.
Affiliations
Universidade de São Paulo (BR)
Corresponding author
Barone, Mark Thomaz Ugliara
Venue
Sleep Science
Published
2018-06
Volume
11
Issue
03
Pages
137-140
ISSN
  • 1984-0063 (ISSN-L)
  • 1984-0659
OpenAlex
W2897272843
Cited by
4
References
19
Citations by year
2023: 1 · 2022: 1 · 2021: 2
FWCI
0.28
Type
journal article
Language
en
Open access
Locations
  • Sleep Science (publishedVersion, cc-by-nc-nd)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
  • Health Sciences › Medicine › Physiology › Thermoregulation and physiological responses
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Keywords
type 1 diabetes, peripheral body temperature, thermoregulation, wrist temperature, temperature amplitude, circadian rhythm, heat dissipation

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