Peripheral body temperature impairment in individuals with type 1 diabetes mellitus
Open accessAbstract
Objective: The aim of the present study was to evaluate the peripheral temperature rhythmicity and control in individuals with type 1 diabetes mellitus. Methods: Twelve non-obese adults (20-40 years old) with type 1 diabetes mellitus (T1D) and eight control individuals, matched for age and BMI, wore a wrist temperature recorder for 10 consecutive days. Recorded data were aggregated to calculate M10 (ten hours of highest temperature) and L5 (five hours of lowest temperature) of wrist temperature values for both groups. Results: Mean wrist temperature and M10 were not different when comparing the groups. The wrist temperature amplitude was reduced in the T1D group (p=0.039), due to a higher L5 (p=0.038). Discussion: While the higher L5 observed in T1D could be explained by less efficient heat dissipation, the amplitude flattening coincides with that observed in elderly.
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The ensuing peripheral vascular disease and neuropathy impair thermoregulation specifically at night.
“The ensuing peripheral vascular disease and neuropathy impair thermoregulation specifically at night32,33.”
From Diurnal rhythms of wrist temperature are associated with future disease risk in the UK Biobank (2023) · cites this paper as [33]
An explanation for some of the strong associations observed in this study might be that small amplitude temperature rhythms diminish thermosensitive gene regulation, which in combination with disease-specific perturbations, like those observed for diabetic neuropathy, lead to the emergence of specific disease phenotypes.
“An explanation for some of the strong associations observed in this study might be that small amplitude temperature rhythms diminish thermosensitive gene regulation, which in combination with disease-specific perturbations, like those observed for diabetic neuropathy,32,33 lead to the emergence of specific disease phenotypes.”
From Diurnal rhythms of wrist temperature are associated with future disease risk in the UK Biobank (2023) · cites this paper as [33]
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References 19 · Cited by 4
Research works printed but not linked: 1
- [8]Colwell CS Circadian Medicine New York Wiley-Blackwell 2015
- Authors
- Barone, M. T. U., Gonçalves, B., & Menna-Barreto, L.
- Affiliations
- Universidade de São Paulo (BR)
- Corresponding author
- Barone, Mark Thomaz Ugliara
- Venue
- Sleep Science
- Publisher
- Georg Thieme Verlag KG
- Published
- 2018-06
- Volume
- 11
- Issue
- 03
- Pages
- 137-140
- ISSN
- 1984-0063 (ISSN-L)
- 1984-0659
- PMC
- PMC6201516
- OpenAlex
- W2897272843
- Cited by
- 4
- References
- 19
- Citations by year
- 2023: 1 · 2022: 1 · 2021: 2
- FWCI
- 0.28
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Sleep Science (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Health Sciences › Medicine › Physiology › Thermoregulation and physiological responses
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- type 1 diabetes, peripheral body temperature, thermoregulation, wrist temperature, temperature amplitude, circadian rhythm, heat dissipation
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