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Cited by 26Cardiovascular Disease and AdiposityCardiovascular Health and Disease PreventionDiabetes, Cardiovascular Risks, and Lipoproteins

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Indicators of Abdominal Adiposity and Carotid Intima-Media Thickness: Results from the Longitudinal Study of Adult Health (ELSA-Brazil)

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Eickemberg, Michaela, Amorim, Leila Denise Alves Ferreira, Almeida, Maria da Conceição Chagas de, Aquino, Estela Maria Leão de, Fonseca, Maria de Jesus Mendes da, Santos, Itamar de Souza, Chor, Dora, Diniz, Maria de Fátima Sander, Barreto, Sandhi Maria, Matos, Sheila Maria Alvim de·2018·Arquivos Brasileiros de Cardiologia
DOI 10.5935/abc.20180273PMC PMC6424038
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Abstract

BACKGROUND: Abdominal adiposity is a risk factor for cardiovascular disease. OBJECTIVE: To determine the magnitude of the association between abdominal adiposity, according to five different indicators, and the carotid intima-media thickness (CIMT). METHODS: Data from 8,449 participants aged 35 to 74 years from the ELSA-Brazil study were used. The effect of waist circumference (WC), waist-to-hip ratio (WHR), conicity index (C index), lipid accumulation product (LAP) and visceral adiposity index (VAI) on CIMT were evaluated. Data were stratified by gender and analyzed using multivariate linear and logistic regressions. A significance level of 5% was considered. RESULTS: Participants with CIMT > P75 showed a higher frequency of abdominal adiposity (men >72% and women >66%) compared to those with CIMT < P75. Abdominal adiposity was associated with the mean CIMT, mainly through WC in men (0.04; 95%CI: 0.033; 0.058). The abdominal adiposity identified by the WC, WHR, LAP, and VAI indicators in women showed an effect of 0.02 mm on the CIMT (WC: 0.025, 95%CI: 0.016, 0.035; WHR: 0.026, 95%CI: 0.016, 0.035; LAP: 0.024, 95%CI: 0.014; 0.034; VAI: 0.020, 95%CI: 0.010, 0.031). In the multiple logistic regression, the abdominal adiposity diagnosed by WC showed an important effect on the CIMT in both genders (men: OR = 1.47, 95%CI: 1.22-1.77, women: OR = 1.38; 95%CI: 1.17-1.64). CONCLUSION: Abdominal adiposity, identified through WC, WHR, LAP, and VAI, was associated with CIMT in both genders, mainly for the traditional anthropometric indicator, WC.

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  • Polycystic ovary syndrome (PCOS) is associated with an increased risk of cardiovascular diseases (CVD).

    “Polycystic ovary syndrome (PCOS) is associated with an increased risk of cardiovascular diseases (CVD).”

    From Association of dietary phytochemical index with metabolic markers, serum asymmetric dimethylarginine and atherogenic indices in patients with polycystic ovary syndrome (2025) · cites this paper as [5]

    The Introduction discusses abdominal obesity as a cardiovascular risk factor, and the Results examine abdominal adiposity and carotid intima-media thickness. Neither addresses PCOS or its association with cardiovascular disease; searches for “PCOS” and “polycystic ovary syndrome” found no relevant passage in our copy. Page numbers were not provided. (LLM, conf=0.76)

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Metadata

Authors
Eickemberg, M., Amorim, L. D. A. F., Almeida, M. D. C. C. D., Aquino, E. M. L. D., Fonseca, M. D. J. M. D., Santos, I. D. S., Chor, D., Diniz, M. D. F. S., Barreto, S. M., & Matos, S. M. A. D.
Affiliations
  • Universidade Federal da Bahia (BR)
  • Universidade Federal de Minas Gerais (BR)
Corresponding author
Eickemberg, Michaela
ORCID
Venue
Arquivos Brasileiros de Cardiologia
Publisher
Sociedade Brasileira de Cardiologia
Published
2018
Volume
112
Issue
3
Pages
220-227
ISSN
0066-782X (ISSN-L)
DOI
10.5935/abc.20180273
PMC
PMC6424038
OpenAlex
W2903831837
Cited by
26
References
1
Citations by year
2025: 6 · 2023: 6 · 2022: 3 · 2021: 5 · 2020: 6
FWCI
2.08
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Arquivos Brasileiros de Cardiologia (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (publishedVersion, other-oa)
  • Americanae (AECID Library) (submittedVersion, other-oa)
  • Arca - Repositório Institucional da Fiocruz (submittedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, other-oa)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
abdominal fat, carotid intima-media thickness, waist circumference, waist-to-hip ratio, conicity index, lipid accumulation product, visceral adiposity index, cardiovascular risk, anthropometric indicators, sex differences, adults, atherosclerosis, cardiovascular risk factors, longitudinal cohort, Brazil, São Paulo state, Paraná, Rio de Janeiro state
MeSH terms
Adult, Aged, Brazil, Female, Humans, Lipids, Longitudinal Studies, Male, Middle Aged, Risk Factors, Biomarkers, Obesity, Abdominal, Carotid Intima-Media Thickness, Lipid Accumulation Product

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