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Cited by 22Renal Transplantation Outcomes and TreatmentsOrgan Transplantation Techniques and OutcomesOrgan Donation and Transplantation

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Perioperative-, Recipient-, and Donor-Related Factors Affecting Delayed Graft Function in Kidney Transplantation

the Department of Anaesthesiology and Intensive Care Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, Aceto, Paola, Perilli, Valter, Luca, Ersilia, Salerno, Maria Paola, Punzo, Giovanni, Ceaichisciuc, Ina, Cataldo, Andrea, Lai, Carlo, Citterio, Franco, Sollazzi, Liliana·2019·Experimental and Clinical Transplantation
DOI 10.6002/ect.2018.0225
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Abstract

Objectives Delayed graft function is a frequent complication in deceased-donor kidney transplant, with an incidence ranging from 10% to 50% among different centers; it is also associated with lower graft survival. In this study, we aimed to identify risk factors for delayed graft function, particularly those associated with perioperative management (including cold ischemia time) and nonmodifiable recipient- and donor-related factors. The effects of delayed graft function on graft and patient outcomes were also evaluated. Materials and methods Our retrospective analyses included 125 adult patients who underwent deceased-donor kidney transplant. Delayed graft function was diagnosed if at least 1 dialysis treatment was required during the first week posttransplant according to Perico's definition. Results Prevalence of delayed graft function was 30.4% (n = 38). Cold ischemia time was significantly prolonged in patients with delayed graft function compared with those without it. Multivariate regression showed that cold ischemia time was the only predictor of delayed graft function. A cutoff of 9 hours and 12 minutes was found as a limit beyond which delayed graft function occurred (sensitivity = 90%; specificity = 29%; area under the curve = 0.68). Greater donor and recipient age and longer pretransplant dialysis time in recipients were associated with occurrence of delayed graft function. In patients with delayed graft function, hospital stay duration was significantly greater a…

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  • The experience of kidney transplantation may be strongly emotional, accompanied by difficulty accepting the new organ, lifestyle changes, side-effects, anxiety, depression, redefinition of body, and change in social and family roles.

    “However, the experience may be a strongly emotional one, accompanied by difficulty in accepting the new organ, lifestyle changes, the side-effects associated with the procedure, anxiety, depression, the redefinition of one’s body, and a change in social and family roles [1,2,3,4,5].”

    From Effectiveness of Expressive Writing in Kidney Transplanted Patients: A Randomized Controlled Trial Study (2022) · cites this paper as [2]

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Research works printed but not linked: 23

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Metadata

Authors
the Department of Anaesthesiology and Intensive Care Medicine, F. P. U. A. G. I., Aceto, P., Perilli, V., Luca, E., Salerno, M. P., Punzo, G., Ceaichisciuc, I., Cataldo, A., Lai, C., Citterio, F., & Sollazzi, L.
Affiliations
Agostino Gemelli University Polyclinic (IT)
ORCID
Venue
Experimental and Clinical Transplantation
Publisher
Baskent University
Published
2019-02-22
Volume
17
Issue
5
Pages
575-579
ISSN
  • 1304-0855 (ISSN-L)
  • 2146-8427
DOI
10.6002/ect.2018.0225
OpenAlex
W2915348570
Cited by
22
References
1
Citations by year
2026: 2 · 2025: 4 · 2024: 1 · 2023: 5 · 2022: 3 · 2021: 4 · 2020: 3
FWCI
2.19
Type
journal article
Language
en
Open access
closed
Locations
  • Experimental and Clinical Transplantation (publishedVersion)
  • PubMed (publishedVersion)
  • IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
Topics
  • Health Sciences › Medicine › Transplantation › Renal Transplantation Outcomes and Treatments
  • Health Sciences › Medicine › Surgery › Organ Transplantation Techniques and Outcomes
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Organ Donation and Transplantation
Keywords
delayed graft function, kidney transplantation, deceased donor kidney, cold ischemia time, risk factors, graft survival, perioperative care, recipient age, donor age, pretransplant dialysis, length of hospital stay, pulsatile perfusion
MeSH terms
Adult, Aged, Female, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors, Kidney Transplantation, Patient Selection, Donor Selection, Cold Ischemia, Delayed Graft Function, Preoperative Period

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