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Cited by 462

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Preparation and comprehensive characterization of a calcium hydroxyapatite reference material

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Markovic, M., Fowler, B.O., Tung, M.S.·2004·Journal of Research of the National Institute of Standards and Technology

Abstract

Numerous biological and chemical studies involve the use of calcium hydroxyapatite (HA), Ca10(PO4)6(OH)2. In this study detailed physicochemical characterization of HA, prepared from an aqueous solution, was carried out employing different methods and techniques: chemical and thermal analyses, x-ray diffraction, infrared and Raman spectroscopies, scanning and transmission microscopies, and Brunauer, Emmett, and Teller (BET) surface-area method. The contents of calcium (Ca(2+)), phosphate (PO4 (3-)), hydroxide (OH(-)), hydrogenphosphate (HPO4 (2-)), water (H2O), carbonate (CO3 (2-)), and trace constituents, the Ca/P molar ratio, crystal size and morphology, surface area, unit-cell parameters, crystallinity, and solubility of this HA were determined. This highly pure, homogeneous, and highly crystalline HA is certified as a National Institute of Standards and Technology (NIST) standard reference material, SRM 2910.

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Metadata

Authors
Markovic, M., Fowler, B. O., & Tung, M. S.
Venue
Journal of Research of the National Institute of Standards and Technology
Published
2004-11
Volume
109
Issue
6
Pages
553
ISSN
1044-677X (ISSN-L)
OpenAlex
W2323613579
Cited by
462
References
1
FWCI
4.04
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Preparation and comprehensive characterization of a calcium hydroxyapatite reference material. https://app.cochat.ai/papers/10.6028/jres.109.042
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Markovic, M., Fowler, B. O., & Tung, M. S. (2004). Preparation and comprehensive characterization of a calcium hydroxyapatite reference material. Journal of Research of the National Institute of Standards and Technology. https://doi.org/10.6028/jres.109.042

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