Fluoxetine ameliorates dysbiosis in a depression model induced by chronic unpredicted mild stress in mice

Sun, Lijuan; Zhang, Haohao; Cao, Ying; Wang, Chenchen; Zhao, Changhai; Wang, Huaning; Cui, Guangbin; Wang, Meixia; Pan, Yan; Shi, Yupeng; Nie, Yongzhan

doi:10.7150/ijms.37322

Fluoxetine ameliorates dysbiosis in a depression model induced by chronic unpredicted mild stress in mice

Background: Accumulating evidence has shown that neuropsychiatric disorders are associated with gut microbiota through the gut-brain axis. However, the effects of antidepressant treatment on gut microbiota are rarely studied. Here, we investigated whether stress led to gut microbiota changes and …