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Liver-targeted degradation of BRD4 reverses hepatic fibrosis and enhances metabolism in murine models
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This strategy has been successfully applied to degrade intracellular targets like BRD4 in hepatic stellate cells, reversing hepatic fibrosis in murine models.
“This strategy has been successfully applied to degrade intracellular targets like BRD4 in hepatic stellate cells, reversing hepatic fibrosis in murine models93”
From Emerging strategies in senotherapeutics: from broad-spectrum senolysis to precision reprogramming (2026) · cites this paper as [93]
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Sorted by citations
Emerging strategies in senotherapeutics: from broad-spectrum senolysis to precision reprogramming
Zhang, W., Song, S., Zhang, Y., Pan, Y., Hu, D., & Wang, Y. (2026) · npj Aging · doi:10.1038/s41514-026-00355-z · Cited by 6
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Metadata
- Authors
- Yuan, S., Nisar, A., Chen, C., Dong, X., Pan, Y., Zi, M., Wang, Q., Khan, S., Guo, Y., Zhang, X., & He, Y.
- Venue
- Theranostics
- Publisher
- Ivyspring International Publisher
- Published
- 2025-06-18
- Volume
- 15
- Issue
- 15
- Pages
- 7270-7290
- ISSN
- 1838-7640
- PMC
- PMC12315693
- Cited by
- 22
- References
- 0
- Language
- en
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