Melatonin Treatment Improves Mesenchymal Stem Cells Therapy by Preserving Stemness during Long-term In Vitro Expansion

Shuai, Yi, Liao, Li, Su, Xiaoxia, Yu, Yang, Shao, Bingyi, Jing, Huan, Zhang, Xinjing, Deng, Zhihong +1 more·2016·Theranostics

DOI 10.7150/thno.15412

Cited by (137)

Items 101–137 of 137

Melatonin attenuates dental pulp stem cells senescence due to vitro expansion via inhibiting MMP3
Zeying Zhang, Yandong Bao, Penggong Wei, Xiaoyuan Yan, Qiujing Qiu, Lihong Qiu · 2023 · Oral Diseases
Melatonin having Therapeutic Bone Regenerating Capacity in Biomaterials
Jinming Huang, Yi Li, Chengqi He · 2021 · Current Pharmaceutical Biotechnology
Alleviating D-Galactose-Induced Aging in Mice by Modulating Gut-Liver Axis Using Lactiplantibacillus plantarum TY-Y10
Shaoqi Shi, Xiaoxia Li, Feng Zhang, Zhengqiang Jiang, Jing Wang, Liang Zhao, Juan Chen, Xi Shu, Bing Fang, Ping Liu et al. · 2024 · Foods
Melatonin as an oncostatic agent: Review of the modulation of tumor microenvironment and overcoming multidrug resistance
Niloufar Targhazeh, Karla J. Hutt, Amy Winship, Russel Joseph Reiter, Bahman Yousefi · 2022 · Biochimie
Circadian Dysregulation and Melatonin Rhythm Suppression in the Context of Aging
Russel Joseph Reiter, Sergio Rosales‐Corral, Dun Xian Tan, Moisés Alejandro Alatorre-Jiménez, Carlos Alberto Lopez · 2017 · Healthy ageing and longevity
Effect of in vivo culture conditions on the proliferation and differentiation of rat adipose-derived stromal cells
Chao Wang, Tian Xie, Xiaoming Li, Xue Lü, Changxue Xiao, Ping Liu, Feng Xu, Bo Zhang · 2024 · Mechanisms of Ageing and Development
Yes-associated protein-mediated melatonin regulates the function of periodontal ligament stem cells under oxidative stress conditions
Ke Gu, Xiaomei Feng, Shao-Qing Sun, Xingyao Hao, Yong Wen · 2024 · World Journal of Stem Cells
Decorin inhibits the insulin-like growth factor I signaling in bone marrow mesenchymal stem cells of aged humans
Tze-Hong Wong, Ting‐Yu Chen, Kuo‐Yun Tseng, Zih-Ying Chen, Chung–Hsing Chen, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin · 2020 · Aging
Melatonin and mesenchymal stem cells co-administration alleviates chronic obstructive pulmonary disease via modulation of angiogenesis at the vascular-alveolar unit
Mira Hanna, Sabreen Sayed Elnassag, Dina Hisham Mohamed, Marawan A. Elbaset, Olfat Gamil Shaker, Effat A. Khowailed, Sarah Ali Abdelhameed Gouda · 2024 · Pflügers Archiv - European Journal of Physiology
Construction, Characterization, and Regenerative Application of Self-Assembled Human Mesenchymal Stem Cell Aggregates
Shijie Li, Peisheng Liu, Ting Zhu, Bing‐Dong Sui, Yan J. Jin, Kun Xuan, Chenxi Zheng · 2023 · Journal of Visualized Experiments
Melatonin selectively influences the transcription of pluripotency and differentiation markers in human non-cancer cells
Georgi Nikolaev, Elena Marinova, Rossitza Konakchieva, Plamen Todorov · 2019 · Biotechnology & Biotechnological Equipment
Short-term use of resveratrol in alloplastic graft material applied with calvarial bone defects in rats
Nihat Laçin, Engin Devecí · 2019 · Acta Cirúrgica Brasileira
Postmenopausal Osteoporosis: A Mini Review
Yi Shuai, Zhang Zhang, Tao Guo, Rui Yang, Jin Lei, Wenjia Liu · 2019 · EMJ Rheumatology
Melatonin and angiogenesis potential in stem cells
Somayyeh Rashidi, Sara Aghakhani Chegeni, Golbarg M. Roozbahani, Reza Rahbarghazi‬, Aysa Rezabakhsh, Russel Joseph Reiter · 2025 · Stem Cell Research & Therapy
EMF treatment delays mesenchymal stem cells senescence during long-term in vitro expansion by modulating autophagy
Wenxiang Cai, Yifan Xiao, Jiyuan Yan, Hao Fan Peng, Chang Tu · 2024 · Frontiers in Cell and Developmental Biology
Bone progeria diminished the therapeutic effects of bone marrow mesenchymal stem cells on retinal degeneration
Chun-Lei Deng, Cheng-Biao Hu, Bao-Ying Wang, Ye-Cheng Xiong, Tao Chen, Na Zhao, Li-Hui Bao, Rui Quan, Fangying Du, Bing‐Dong Sui et al. · 2020 · Biochemical and Biophysical Research Communications
The role of mesenchymal stem cells and quercetin in preserving fertility in prepubertal male mice exposed to cyclophosphamide
Amirreza Jourabchi, Morteza Abdi, Leila Roshanghar, Homa Aminzadeh Ghavifekr · 2025 · Naunyn-Schmiedeberg s Archives of Pharmacology
Functionalized ZIF-8 modulates the oxidative stress microenvironment in osteoporosis to enhance osseointegration
Youbin Li, Xin Li, Tengyue Liu, Chengzhe Yang, Qiang Gao, Lanfeng Huang · 2026 · Materials Today Advances
Growth Plate Injuries: Advances and Future Directions in Regenerative Medicine
Mehdi Rasouli, Joseph C. Wenke · 2025 · Annals of Biomedical Engineering
A Review of Ionizing Radiation-Induced Senescence of Bone Marrow Mesenchymal Stem/Stromal Cells: Mechanisms and Therapeutic Strategies
Xiaoliang Li, Maoshan Chen, Yangyang Zhang, Jiuxuan Li, Lixin Xiang, Yanni Xiao, Yang Xiang, Li Chen, Qian Ran, Zhongjun Li · 2026 · Current Issues in Molecular Biology
Melatonin Attenuates H2O2-Induced Oxidative Stress by Restoring Redox Balance, Mitochondrial Integrity and Reducing Apoptosis in Buffalo Fibroblasts
Priya Dahiya, Manu Mangal, Srishti Bhatia, Neha Sharma, Ashish Sindhu, Bhavya Magoo, Meeti Punetha, Renu Bala, Pradeep Kumar, Dharmendra Kumar · 2026 · Antioxidants
Research progress in direct regeneration technology of LiFePO4 from spent lithium batteries
Jiaxing Han, Wentao Li, Shuo Gao, Weijian Zhang, Yanpeng Yin, Jing Wu, Suhong Gui, Aigang Zhen, Wei Zhang, Jinlong Zhang et al. · 2026 · Journal of Industrial and Engineering Chemistry
Effects of different doses of melatonin on rat adipose derived mesenchymal stem cells
Nazlı Çil, Mutlu Yaka, Nazire Gül Neşet, Mücahit Seçme, Gülçin Abban Mete · 2021 · Hormone Molecular Biology and Clinical Investigation
Differentiation of Adipose-Derived Mesenchymal Stem Cells into Neuron-Like Cells induced by using β-mercaptoethanol
Maeda H. Mohammad, Ahmed Majeed Al-Shammari, Rafal H Abdulla, Aesar A. Ahmed, Aseel Khalid · 2020 · Baghdad Science Journal
Immunomodulatory effects of intestinal mesenchymal cells in the context of inflammatory bowel disease
Belal Chami, Paul Kenneth Witting · 2021 · Acta Physiologica
Modulation of mesenchymal stem cells protection against senescence during long-term expansion by the PI3K/Akt signaling
Yi Luo, Xinxin Zhu, Jian‐Hui Xiao · 2023 · Research Square
Hormonal impacts on stem cell lineages and related signaling pathways
Shreya Maity, Sukhendu Maity, Kousik Pramanick · 2023 · Elsevier eBooks
Melatonin-Coated Nanofiber Cell Sheets Promote Alveolar Bone Regeneration Through ROS Scavenging and Preservation of Stemness
Weibing Tang, Fangjun Huo, Rongbai Ju, Xinghui Gao, Min He, Jie Long, Siyuan Zhang, Weidong Tian · 2024 · SSRN Electronic Journal
Effect of melatonin on oxidative stress of differentiated Dopaminergic cells
Hadeer Ahmed Mohamed Ibrahim, Abdelaziz M. Hussein, Mahmoud Gabr, A. F. Abdel-Aziz, Rasha Aly El-Saeed · 2023 · Egyptian Pharmaceutical Journal
L-ascorbic acid (LAA) Supplementation in Adipose-Tissue Mesenchymal Stem Cells (AT-MSC) Culture Induce Proliferation and Prevent Cellular Senescent without Altering Mesenchymal Stem Cells (MSC) Characterization
Komang Ardi Wahyuningsih, I Gede Eka Wiratnaya, I Wayan Weta, I Gede Raka Widiana, Wimpie I. Pangkahila, Ida Ayu Ika Wahyuniari, I Made Muliarta, Veronika Maria Sidharta, Retnaningtyas Siska Dianty · 2025 · Research Square
Additional file 2 of CD146 controls the quality of clinical grade mesenchymal stem cells from human dental pulp
Ma, Lan, Huang, Zhiqing, Wu, Di, Xiaoxing Kou, Mao, Xueli, Shi, Songtao · 2021 · Figshare
Additional file 1 of Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process
Tan, Yi-Zhou, Xu, Xin-Yue, Dai, Ji-Min, Yuan Yin, He, Xiao-Tao, Zhang, Yi-Lin, Zhu, Tian-Xiao, An, Ying, Beimin Tian, Chen, Fa-Ming · 2021 · Figshare
Additional file 2 of Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process
Tan, Yi-Zhou, Xu, Xin-Yue, Dai, Ji-Min, Yin, Yuan, He, Xiao-Tao, Zhang, Yi-Lin, Zhu, Tian-Xiao, An, Ying, Beimin Tian, Chen, Fa-Ming · 2021 · Figshare
Additional file 3 of Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process
Tan, Yi-Zhou, Xu, Xin-Yue, Dai, Ji-Min, Yin, Yuan, He, Xiao-Tao, Zhang, Yi-Lin, Zhu, Tian-Xiao, An, Ying, Beimin Tian, Chen, Fa-Ming · 2021 · Figshare
Additional file 1 of CD146 controls the quality of clinical grade mesenchymal stem cells from human dental pulp
Ma, Lan, Huang, Zhiqing, Di Wu, Xiaoxing Kou, Mao, Xueli, Shi, Songtao · 2021 · Figshare
Additional file 4 of Melatonin induces the rejuvenation of long-term ex vivo expanded periodontal ligament stem cells by modulating the autophagic process
Tan, Yi-Zhou, Xu, Xin-Yue, Dai, Ji-Min, Yin, Yuan, He, Xiao-Tao, Zhang, Yi-Lin, Zhu, Tian-Xiao, An, Ying, Beimin Tian, Chen, Fa-Ming · 2021 · Figshare
Astragaloside IV pretreatment enhances the therapeutic efficacy of bone marrow mesenchymal stem cells in murine fulminant hepatic failure
Tingting Zhao, Wen-Qiang He, Rui-Zhi Shi, Bing-Yu Du, Mei-Mei Lan, Dan Zhou, Xiao-Qin Gao, Min Li, JUN-FENG LI, LI-TING ZHANG · 2026 · Molecular Biology Reports