The DOI matches its Crossref record; its reference list is not available.
Optimization of extraction conditions of phytochemical compounds in “Xiem” banana peel powder using response surface methodology
Open accessAbstract
In Vietnam, banana is a popular fruit that is grown and consumed as a ripe fruit or used for cooking.During industrial processing, its peel is removed as a waste product (about 18%-33% of the whole fruit) containing many bioactive compounds useful for human health.The aim of this study was to determine the effects of extraction conditions such as the ratio of solvent to solid (ml/g), extraction temperature ( o C), and extraction time (minutes) on extraction yield such as total polyphenol and flavonoid contents (TPC and TFC, respectively).The response surface methodology and Box-Behnken design were used to optimize the extraction of antioxidant compounds from "Xiem" banana peels cultivated in U Minh district, Cà Mau province, Vietnam.The results showed that the most important variable in the extraction process was solvent concentration.Optimal conditions were found to be 60%, 76:1, 68 o C, and 48 minutes for solvent concentration, solvent-to-solid ratio, temperature, and time, respectively, resulting in the maximum TPC and TFC, 62.41 mgGAE/g and 6.98 mgQE/g, respectively.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“banana peel extract reduces oxidative stress, and thus they are suitable for application in biopharmaceuticals; their potential enhances UV protection in creams.[63]”
From Bioactive, antioxidant, industrial, and nutraceutical applications of banana peel (2023) · cites this paper as [63]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Like temperature was found to have significant impact on extraction of polyphenol content and antioxidant capacity from orange peels”
From Bioactive, antioxidant, industrial, and nutraceutical applications of banana peel (2023) · cites this paper as [63]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
No citation lists for this paper
No citation lists for this paper yet — checked again daily.
References 21 · Cited by 29
Research works printed but not linked: 27
- Perrier X, De Langhe E, Donohue M, Lentfer C, Vrydaghs L, Bakry F, et al. Multidisciplinary perspectives on banana (Musa spp.) domestication. Proc Natl Acad Sci 2011;108(28):11311-8.
- González-Montelongo R, Lobo MG, González M. Antioxidant activity in banana peel extracts: testing extraction conditions and related bioactive compounds. Food Chem 2010;119(3):1030-9.
- Tsamo CVP, Herent MF, Tomekpe K, Emaga TH, Quetin-Leclercq J, Rogez H, et al. Phenolic profieling in the pulp and peel of nine plantain cultivars (Musa sp.). Food Chem 2015;167:197-204.
- Oliveira L, Freire CSR, Silvestre AJ, Cordero N. Lipophilic extracts from banana fruit residues: a source of valuable phytosterols. J Agric Food Chem 2008;56:9520-5.
- Someya S, Yoshiki Y, Okubo K. Antioxidant compounds from bananas (Musa cavendish). Food Chem 2002;79:351-4.
- Gan C, Latiff AA. Optimization of the solvent extraction of bioactive compounds from Parkia speciosa pod using response surface methodology. Food Chem 2011;124:1277-83.
- Wang J, Sun B, Cao Y, Tian Y, Li X. Optimization of ultrasound- assisted extraction of phenolic compounds from wheat bran. Food Chem 2008;106(2):804-10.
- Irakli M, Chatzopoulou P, Ekateriniadou L. Optimization of ultrasound- assisted extraction of phenolic compounds: oleuropein, phenolic acids, phenolic alcohols and flavonoids from olive leaves and evaluation of its antioxidant activities. Ind Crops Prod 2018;124:382-8.
- Goltz C, Ávila S, Barbieri JB, Igarashi-Mafra L, Mafra MR. Ultrasound-assisted extraction of phenolic compounds from Macela (Achyrolcine satureioides) extracts. Ind Crops Prod 2018;115:227-34. Figure 6: The overlay plot for TPC and TPC in extract at different conditions.
- Thoo YY, Ho SK, Liang JY, Ho CW, Tan CP. Effects of binary solvent extraction system, extraction time and 12 extraction temperature on phenolic antioxidants and antioxidant capacity from mengkudu (Morinda citrifolia). Food Chem 2010;120:290-5.
- Vuong QV, Golding JB, Stathopoulos CE, Nguyen MH, Roach PD. Optimizing conditions for the extraction of catechins from green tea using hot water. J Sep Sci 2011;34(21):3099-106.
- Roselló-Soto E, Martí-Quijal FJ, Cilla A, Munekata PE, Lorenzo JM, Remize F, et al. Influence of temperature, solvent and pH on the selective extraction of phenolic compounds from tiger nuts by- products: Triple-TOF-LC-MS-MS characterization. Molecules 2019;24(4):797.
- Jeong SM, Kim SY, Kim DR, Jo SC, Nam KC, Ahn DU, et al. Effect of heat treatment on the antioxidant activity of extracts from citrus peels. J Agric Food Chem 2004;52(11):3389-93.
- Wong YS, Sia CH, Khoo HE, Ang YK, Chang SK, Yim HS. Influence of extraction conditions on antioxidant properties of passion fruit (Passiflora edulis) peel. Acta Sci Pol Technol Aliment 2014;13(3):257-65.
- Myers RH, Montgomery DC, Anderson-Cook CM. Response surfacemethodology: process and product optimization using designedexperiments. John Wiley & Sons, Hoboken, NJ, 2016.
- Fu L, Xu BT, Xu XR, Gan RY, Zhang Y, Xia EQ, et al Antioxidant capacities and total phenolic contents of 62 fruits. Food Chem 2011;129(2):345-50.
- Mandal B, Madan S. Preliminary phytochemical screening and evaluation of free radical scavenging activity of Stevia rebaudiana Bertoni from different geographical sources. J Pharmacogn Phytochem 2013;2 (1): 14-9.
- Makasana J, Dholakiya BZ, Gajbhiye NA, Raju S. Extractive determination of bioactive flavonoids from butterfly pea (Clitoria ternatea Linn.). Rese Chem Intermed 2017;43:783-99.
- Wang L, Wang Z, Li X. Optimization of ultrasonic-assisted extraction of phenolic antioxidants from Malus baccata (Linn.) Borkh. using response surface methodology. J Sep Sci 2013;36:1652-58.
- Zabeti M, Daud WM, Aroua MK. Optimization of the activity of CaO/Al2O3catalyst forbiodiesel production using response surface method-ology. Appl Catal Gen 2009;366:154-9.
- Mota I, Rodrigues Pinto PC, Novo C, Sousa G, Guerreiro O, Guerra AR, et al. Extraction of polyphenolic compounds from Eucalyptus globulus bark: process optimization and screening for biological activity. Ind Eng Chem Res 2012;51:6991-7000.
- Alfarsi MA, Lee CY. Optimization of phenolics and dietary fibre extraction from date seeds. Food Chem 2008;108:977-85.
- Silva EM, Souza JNS, Rogez H, Rees JF, Larondelle Y. Antioxidant activities and polyphenolic contents of fifteen selected plant species from the Amazonian region. Food Chem 2007;101:1012-8.
- Naczk M, Shahidi F. Extraction and analysis of phenolics in food. J Chromatogr A 2004;1054(1-2):95-111.
- Gertenbach D. Solid-liquid extraction technologies formanufacturing nutraceuticals. In: Mazza G, Maguer ML Shi J (Eds.). Functional foods: biochemical and processing aspects, CRC Press, Boca Raton, FL, pp 331-66, 2001.
- Galvan d'Alessandro L, Kriaa K, Nikov I, Dimitrov K. Ultrasound assisted extraction of polyphenols from black chokeberry. Sep Purif Technol 2012;93:42-7.
- Pingret D, Fabiano-Tixier AS, Chemat F. Degradation during application of ultrasound in food processing: a review. Food Control 2013;31:593-606.
Metadata
- Authors
- Tai, N. V., Linh, M. N., & Thuy, N. M.
- Venue
- Journal of Applied Biology & Biotechnology
- Publisher
- Open Science Publishers LLP
- Published
- 2021-11-10
- ISSN
- 2347-212X (ISSN-L)
- OpenAlex
- W3214578066
- Cited by
- 29
- References
- 21
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 8 · 2023: 15 · 2022: 3
- FWCI
- 3.55
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- Locations
- Journal of Applied Biology & Biotechnology (publishedVersion, cc-by-nc-sa)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food Quality and Safety Studies
- Keywords
- banana peel, phytochemical extraction, total polyphenols, total flavonoid content, antioxidants, extraction optimization, solid-to-solvent ratio, extraction temperature, extraction time, fruit waste valorization
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Optimization of extraction conditions of phytochemical compounds in “Xiem” banana peel powder using response surface methodology. https://app.cochat.ai/papers/10.7324/jabb.2021.9607
- The paper
- Tai, N. V., Linh, M. N., & Thuy, N. M. (2021). Optimization of extraction conditions of phytochemical compounds in “Xiem” banana peel powder using response surface methodology. Journal of Applied Biology & Biotechnology. https://doi.org/10.7324/jabb.2021.9607