The DOI matches its Crossref record.
Bone Disease in Alcohol Abuse
Abstract
We evaluated bone disease in eight white men between the ages of 49 and 61 years who had been abusing alcohol for at least 10 years. The mean density of vertebral cancellous bone was 58% of normal, whereas the mean density of appendicular cortical bone was 90% of normal. Marked reduction in active bone resorption and bone formation was seen without evidence of osteomalacia. Serum levels of calcium and magnesium were in the lower range of normal; serum levels of phosphorus, calcifediol, and calcitriol were normal; and serum levels of parathyroid hormone and nephrogenous cyclic adenosine monophosphate were in the higher range of normal. These data suggest that bone disease in these subjects is not due to inhibition of parathyroid hormone secretion or function, or abnormal vitamin D metabolism, but to an inhibition of bone remodeling by a mechanism independent of the calciotropic hormones.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Human Aging: Usual and Successful
Rowe, J. W., & Kahn, R. L. (1987) · Science · doi:10.1126/science.3299702 · Cited by 3,384
Riggs, B. L., & Melton, L. J. (1986) · New England Journal of Medicine · doi:10.1056/nejm198606263142605 · Cited by 1,915
Secondary Causes of Osteoporosis
FITZPATRICK, L. A. (2002) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(11)62214-3 · Cited by 311
Ethanol reduces bone formation and may cause osteoporosis
Diamond, T., Stiel, D., Lunzer, M., Wilkinson, M., & Posen, S. (1989) · The American Journal of Medicine · doi:10.1016/0002-9343(89)90297-0 · Cited by 277
Gallego-Rojo, F. J., Gonzalez-Calvin, J. L., Muñoz-Torres, M., Mundi, J. L., Fernandez-Perez, R., & Rodrigo-Moreno, D. (1998) · Hepatology · doi:10.1002/hep.510280315 · Cited by 241
Metadata
- Authors
- BIKLE, D. D., GENANT, H. K., CANN, C., RECKER, R. R., HALLORAN, B. P., & STREWLER, G. J.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1985-07-01
- Volume
- 103
- Issue
- 1
- Pages
- 42-48
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2032430933
- Cited by
- 309
- References
- 0
- FWCI
- 23.81
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Bone Disease in Alcohol Abuse. https://app.cochat.ai/papers/10.7326/0003-4819-103-1-42
- The paper
- BIKLE, D. D., GENANT, H. K., CANN, C., RECKER, R. R., HALLORAN, B. P., & STREWLER, G. J. (1985). Bone Disease in Alcohol Abuse. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-103-1-42
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
