The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Infection by the Retrovirus Associated with the Acquired Immunodeficiency Syndrome: Clinical, Biological, and Molecular Features
Abstract
Peripheral mononuclear cells from more than 160 persons from groups at risk for the acquired immunodeficiency syndrome (AIDS) have yielded AIDS-associated retroviruses (ARV). Antibodies to ARV can also be found in these risk groups. Antibody-negative, virus-positive persons have been identified with early infection or possible viremia with immune complex formation. Established lines of human T and B cells, monocytes, and promyelocytes have been infected with ARV. Moreover, infectious virus has been recovered from macrophages cultured from the blood of some persons with AIDS. The cytopathic effects of ARV in T cells is associated with the accumulation of unintegrated viral forms in the infected cells. The ARV has also been isolated from plasma, serum, saliva, semen, urine, cerebrospinal fluid, and brain tissue. All these results reflect the wide host range of ARV and support its role in neurologic abnormalities seen in some patients. Molecular studies of independent ARV isolates indicate a polymorphism of nucleotide sequences, particularly in the viral envelope region. All these features place ARV in the lentivirus subfamily of human retroviruses.
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Cites
Poiesz, B. J., Ruscetti, F. W., Gazdar, A. F., Bunn, P. A., Minna, J. D., & Gallo, R. C. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.12.7415 · Cited by 5,043
Cited by
In search of the ‘missing self’: MHC molecules and NK cell recognition
Ljunggren, H.-G., & Kärre, K. (1990) · Immunology Today · doi:10.1016/0167-5699(90)90097-s · Cited by 2,687
CD8 + Lymphocytes Can Control HIV Infection in Vitro by Suppressing Virus Replication
Walker, C. M., Moody, D. J., Stites, D. P., & Levy, J. A. (1986) · Science · doi:10.1126/science.2431484 · Cited by 990
Self-citationPathogenesis of lentivirus infections
Haase, A. T. (1986) · Nature · doi:10.1038/322130a0 · Cited by 566
Epidemiology of HIV Infection and AIDS in the United States
Curran, J. W., Jaffe, H. W., Hardy, A. M., Morgan, W. M., Selik, R. M., & Dondero, T. J. (1988) · Science · doi:10.1126/science.3340847 · Cited by 455
Hoffman, A. D., Banapour, B., & Levy, J. A. (1985) · Virology · doi:10.1016/0042-6822(85)90135-7 · Cited by 443
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Metadata
- Authors
- LEVY, J. A., KAMINSKY, L. S., MORROW, W. J. W., STEIMER, K., LUCIW, P., DINA, D., HOXIE, J., & OSHIRO, L.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1985-11-01
- Volume
- 103
- Issue
- 5
- Pages
- 694-699
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2076387313
- Cited by
- 176
- References
- 1
- FWCI
- 6.52
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Infection by the Retrovirus Associated with the Acquired Immunodeficiency Syndrome: Clinical, Biological, and Molecular Features. https://app.cochat.ai/papers/10.7326/0003-4819-103-5-694
- The paper
- LEVY, J. A., KAMINSKY, L. S., MORROW, W. J. W., STEIMER, K., LUCIW, P., DINA, D., HOXIE, J., & OSHIRO, L. (1985). Infection by the Retrovirus Associated with the Acquired Immunodeficiency Syndrome: Clinical, Biological, and Molecular Features. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-103-5-694
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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