The DOI matches its Crossref record.
Aortic Root Dilatation as a Cause of Isolated, Severe Aortic Regurgitation: Prevalence, Clinical and Echocardiographic Patterns, and Relation to Left Ventricular Hypertrophy and Function
Abstract
To evaluate the relation of aortic root dilatation to aortic regurgitation, we examined clinical, echocardiographic, and radionuclide cineangiographic findings in 102 patients with severe aortic regurgitation. Aortic root dilatation was the only apparent cause in 31 patients (30%), exceeding in prevalence any valvular cause, and was independently associated only with older age (p less than 0.001). Echocardiography showed dilatation to be either localized to the sinuses of Valsalva or to be generalized. At initial evaluation, patients with generalized dilatation had severer abnormalities of left ventricular size and function than those with localized or no dilatation. Aortic valves were subsequently replaced in more patients with generalized than localized dilatation during 28 +/- 17 month follow-up (9 of 15 patients compared with 2 of 15, p less than 0.03). Thus, idiopathic aortic root dilatation is the commonest definable cause of severe aortic regurgitation; aortic root dilatation is associated independently with age but not blood pressure; and generalized aortic root dilatation is associated with marked ventricular dilatation, hypertrophy, and dysfunction.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Lang, R. M., Badano, L. P., Mor-Avi, V., Afilalo, J., Armstrong, A., Ernande, L., Flachskampf, F. A., Foster, E., Goldstein, S. A., Kuznetsova, T., et al. (2015) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2014.10.003 · Cited by 12,362
Lang, R. M., Bierig, M., Devereux, R. B., Flachskampf, F. A., Foster, E., Pellikka, P. A., Picard, M. H., Roman, M. J., Seward, J., Shanewise, J. S., et al. (2005) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2005.10.005 · Cited by 11,318
Self-citationSiu, S. C., & Silversides, C. K. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.12.068 · Cited by 1,028
Clinical significance of the bicuspid aortic valve
Ward, C. (2000) · Heart · doi:10.1136/heart.83.1.81 · Cited by 803
Goldstein, S. A., Evangelista, A., Abbara, S., Arai, A., Asch, F. M., Badano, L. P., Bolen, M. A., Connolly, H. M., Cuéllar-Calàbria, H., Czerny, M., et al. (2015) · Journal of the American Society of Echocardiography · doi:10.1016/j.echo.2014.11.015 · Cited by 641
Self-citation
Metadata
- Authors
- ROMAN, M. J., DEVEREUX, R. B., NILES, N. W., HOCHREITER, C., KLIGFIELD, P., SATO, N., SPITZER, M. C., & BORER, J. S.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1987-06-01
- Volume
- 106
- Issue
- 6
- Pages
- 800-807
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2050987730
- Cited by
- 167
- References
- 0
- FWCI
- 4.18
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Aortic Root Dilatation as a Cause of Isolated, Severe Aortic Regurgitation: Prevalence, Clinical and Echocardiographic Patterns, and Relation to Left Ventricular Hypertrophy and Function. https://app.cochat.ai/papers/10.7326/0003-4819-106-6-800
- The paper
- ROMAN, M. J., DEVEREUX, R. B., NILES, N. W., HOCHREITER, C., KLIGFIELD, P., SATO, N., SPITZER, M. C., & BORER, J. S. (1987). Aortic Root Dilatation as a Cause of Isolated, Severe Aortic Regurgitation: Prevalence, Clinical and Echocardiographic Patterns, and Relation to Left Ventricular Hypertrophy and Function. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-106-6-800
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
