The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Medical Futility: Its Meaning and Ethical Implications
Abstract
The notion of medical futility has quantitative and qualitative roots that offer a practical approach to its definition and application. Applying these traditions to contemporary medical practice, we propose that when physicians conclude (either through personal experience, experiences shared with colleagues, or consideration of published empiric data) that in the last 100 cases a medical treatment has been useless, they should regard that treatment as futile. If a treatment merely preserves permanent unconsciousness or cannot end dependence on intensive medical care, the treatment should be considered futile. Unlike decision analysis, which defines the expected gain from a treatment by the joint product of probability of success and utility of outcome, our definition of futility treats probability and utility as independent thresholds. Futility should be distinguished from such concepts as theoretical impossibility, such expressions as "uncommon" or "rare," and emotional terms like "hopelessness." In judging futility, physicians must distinguish between an effect, which is limited to some part of the patient's body, and a benefit, which appreciably improves the person as a whole. Treatment that fails to provide the latter, whether or not it achieves the former, is "futile". Although exceptions and cautions should be borne in mind, we submit that physicians can judge a treatment to be futile and are entitled to withhold a procedure on this basis. In these cases, physicians should act in concert with other health care professionals, but need not obtain consent from patients or family members.
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“The sad conse-quences of not telling the truth regarding a cancer include depriving the patient of an opportunity for completion of important life-tasks”
From Principles of Clinical Ethics and Their Application to Practice (2021) · cites this paper as [21]
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Cites
Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1985) · Critical Care Medicine · doi:10.1097/00003246-198510000-00009 · Cited by 15,518
APACHE II-A Severity of Disease Classification System
Knaus, W. A., Draper, E. A., Wagner, D. P., & Zimmerman, J. E. (1986) · Critical Care Medicine · doi:10.1097/00003246-198608000-00028 · Cited by 13,379
Beecher, H. K. (1955) · JAMA · doi:10.1001/jama.1955.02960340022006 · Cited by 1,850
Freiman, J. A., Chalmers, T. C., Smith, H., & Kuebler, R. R. (1978) · New England Journal of Medicine · doi:10.1056/nejm197809282991304 · Cited by 1,628
An Evaluation of Outcome from Intensive Care in Major Medical Centers
Knaus, W. A., DRAPER, E. A., WAGNER, D. P., & ZIMMERMAN, J. E. (1986) · Annals of Internal Medicine · doi:10.7326/0003-4819-104-3-410 · Cited by 1,191
Survival after Cardiopulmonary Resuscitation in the Hospital
Bedell, S. E., Delbanco, T. L., Cook, E. F., & Epstein, F. H. (1983) · New England Journal of Medicine · doi:10.1056/nejm198309083091001 · Cited by 860
The Physician's Responsibility toward Hopelessly Ill Patients
Wanzer, S. H., Adelstein, S. J., Cranford, R. E., Federman, D. D., Ed, H., Cg, M., Safar, P. J., Stone, A. A., Taussig, H. B., & van Eys, J. (1984) · New England Journal of Medicine · doi:10.1056/nejm198404123101505 · Cited by 427
In-Hospital Cardiopulmonary Resuscitation
Taffet, G. E. (1988) · JAMA · doi:10.1001/jama.1988.03410140081027 · Cited by 412
Outcomes of Cardiopulmonary Resuscitation in the Elderly
Murphy, D. J., Murray, A. M., Robinson, B. E., & Campion, E. W. (1989) · Annals of Internal Medicine · doi:10.7326/0003-4819-111-3-199 · Cited by 368
Blackhall, L. (1987) · New England Journal of Medicine · doi:10.1056/nejm198711123172009 · Cited by 368
Research works printed but not linked: 10
- . Deciding to Forego Life-Sustaining Treatment: A Report on the Ethical, Medical, and Legal Issues in Treatment Decisions. Washington DC: U.S. Government Printing Office; 1983:60-89.
- Jonsen A, 1987, Pharos., 50, 4
- Lo B, 1989, The Meaning of AIDS, 1, 86
- Weinstein M, 1980, Clinical Decision Analysis.
- Jonsen A . The Old Ethics and the New Medicine. Cambridge: Harvard University Press; 1990.
- 1977, Ethics in Medicine: Historical Perspectives and Contemporary Concerns., 6
- 1981, Republic., 76
- Plum F, 1980, The Diagnosis of Stupor and Coma.
- Katz J, 1984, The Silent World of Doctor and Patient.
- Jecker N, 1990, J Clin Med.
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The APACHE III Prognostic System
Knaus, W. A., Wagner, D. P., Draper, E. A., Zimmerman, J. E., Bergner, M., BASTOS, P. G., Sirio, C., Murphy, D. J., Lotring, T., Damiano, A., et al. (1991) · CHEST Journal · doi:10.1378/chest.100.6.1619 · Cited by 3,539
The APACHE III Prognostic System
Teres, D., & Lemeshow, S. A. (1992) · CHEST Journal · doi:10.1378/chest.102.6.1919b · Cited by 2,896
Principles of Clinical Ethics and Their Application to Practice
Varkey, B. (2021) · Medical Principles and Practice · doi:10.1159/000509119 · Cited by 1,171
Ethnicity and Attitudes Toward Patient Autonomy
Blackhall, L. J. (1995) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1995.03530100060035 · Cited by 1,011
Increasing Incidence of Withholding and Withdrawal of Life Support From the Critically Ill
Prendergast, T. J., & Luce, J. M. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.155.1.9001282 · Cited by 726
Metadata
- Authors
- Schneiderman, L. J., Jecker, N. S., & Jonsen, A. R.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Schneiderman, Lawrence J.
- ORCID
- Jecker, Nancy S.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1990-06-15
- Volume
- 112
- Issue
- 12
- Pages
- 949-954
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2067149985
- Cited by
- 1,215
- References
- 28
- Citations by year
- 2026: 28 · 2025: 29 · 2024: 46 · 2023: 35 · 2022: 38 · 2021: 36 · 2020: 41 · 2019: 55 · 2018: 40 · 2017: 33 · 2016: 39 · 2015: 43 · 2014: 39 · 2013: 44 · 2012: 41
- FWCI
- 15.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Ethics and Legal Issues in Pediatric Healthcare
- Keywords
- futility, treatment decision-making, withholding treatment, decision analysis, physician judgment, informed consent, end-of-life care
- MeSH terms
- Critical Care, Ethics, Medical, Euthanasia, Passive, Family, Humans, Patient Participation, Philosophy, Medical, Physician's Role, Probability, Risk Assessment, Patient Selection, Personal Autonomy, Paternalism, Moral Obligations, Withholding Treatment
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