The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Diagnosing Suffering: A Perspective
Abstract
The alleviation of suffering is crucial in all of medicine, especially in the care of the dying. Suffering cannot be treated unless it is recognized and diagnosed. Suffering involves some symptom or process that threatens the patient because of fear, the meaning of the symptom, and concerns about the future. The meanings and the fear are personal and individual, so that even if two patients have the same symptoms, their suffering would be different. The complex techniques and methods that physicians usually use to make a diagnosis, however, are aimed at the body rather than the person. The diagnosis of suffering is therefore often missed, even in severe illness and even when it stares physicians in the face. A high index of suspicion must be maintained in the presence of serious disease, and patients must be directly questioned. Concerns over the discomfort of listening to patients' severe distress are usually more than offset by the gratification that follows the intervention. Often, questioning and attentive listening, which take little time, are in themselves ameliorative. The information on which the assessment of suffering is based is subjective; this may pose difficulties for physicians, who tend to value objective findings more highly and see a conflict between the two kinds of information. Recent advances in understanding how physicians increase the utility of information and make inferences allow one to reliably use the subjective information on which the diagnosis and treatment of suffering depend. Knowing patients as individual persons well enough to understand the origin of their suffering and ultimately its best treatment requires methods of empathic attentiveness and nondiscursive thinking that can be learned and taught. The relief of suffering depends on physicians acquiring these skills.
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“Because suffering is a personal experience, only the affected individuals can assess whether it is intolerable.20,21”
Citations
Cites
THE NATURE OF SUFFERING AND THE GOALS OF MEDICINE
Cassel, E. J. (1982) · New England Journal of Medicine · doi:10.1056/nejm198203183061104 · Cited by 2,149
The Effect of Race and Sex on Physicians' Recommendations for Cardiac Catheterization
Schulman, K. A., Berlin, J. A., Harless, W., Kerner, J. F., Sistrunk, S., Gersh, B. J., Dubé, R., Taleghani, C. K., Burke, J. E., Williams, S., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199902253400806 · Cited by 1,934
Quality End-of-Life Care: Patients' Perspectives
Singer, P. A., Martin, D. K., & Kelner, M. (1999) · JAMA · doi:10.1001/jama.281.2.163 · Cited by 1,287
The Nature of Suffering and the Goals of Medicine
Cassell, E. J. (1998) · Loss Grief & Care · doi:10.1300/j132v08n01_18 · Cited by 1,178
Self-citationInstitute of Medicine (1997) · National Academies Press eBooks · doi:10.17226/5801 · Cited by 1,079
Doctors' stories: the narrative structure of medical knowledge
Loudon, M. (1991) · Choice Reviews Online · doi:10.5860/choice.29-2135 · Cited by 673
Emanuel, E. J., & Emanuel, L. L. (1998) · The Lancet · doi:10.1016/s0140-6736(98)90329-4 · Cited by 624
Measuring Quality of Care at the End of Life: A Statement of Principles
Lynn, J. (1997) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1997.tb05184.x · Cited by 214
Platt, F. W., & Keller, V. F. (1994) · Journal of General Internal Medicine · doi:10.1007/bf02600129 · Cited by 126
Doctoring: The Nature of Primary Care Medicine
Cassell, E. J. (1997) · DigitalGeorgetown (Georgetown University Library) · doi:10.1093/acprof:oso/9780195113235.001.0001 · Cited by 78
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Herce, R., & Lumbreras, S. (2024) · Scientia et Fides · doi:10.12775/setf.2024.004
“The papers also underscore the significance of subjective information when it comes to diagnosing and addressing suffering, highlighting that mere objective knowledge is insufficient for alleviating distress (Cassell 1999).”
BackgroundApproaching Palliative Sedation at the End of Life
Lebovitz, A., & Vesel, T. (2025) · doi:10.1093/med/9780197681541.003.0032
Psychedelic-assisted therapies for existential and spiritual suffering in palliative care
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“Pain is a physical sensation, measurable and treatable, whereas suffering is a subjective, unique, and individual experience related to a threat to a person’s integrity—not only of the body, but also of identity, social roles, hope, and sense of meaning in life [21, 22].”
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Hinshaw, D. B. (2005) · Clínicas quirúrgicas de Norteamérica
van den Ende, E. S., Schouten, B., Kremers, M. N. T., Cooksley, T., Subbe, C. P., Weichert, I., van Galen, L. S., Haak, H. R., Kellett, J., Alsma, J., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14623457
Vers une (re)considération de la souffrance au travail : une analyse juridico-gestionnaire
Gallinari, F. (2023) · theses.fr (ABES) · doi:10.70675/c532fc15z6488z4f5eza397zd2d28768110c
Psychotherapie bei fortgeschritten erkrankten Krebspatient:innen
Schulz‐Kindermann, F. (2026) · Psychotherapie-Wissenschaft · doi:10.30820/1664-9583-2026-2-43
“Eric Cassell (1999) definiert «Suffering» als einen spezifischen Zustand schwerer Belastung, der mit der unmittelbaren, wahrge-nommenen oder tatsächlichen Bedrohung der Integrität oder existenziellen Kontinuität der Person verbunden ist.”
Jiang, X., Zhang, Q., Yang, Q., Wang, Y., Yang, W., Wei, L., & Wu, Y. (2026) · Research Square · doi:10.21203/rs.3.rs-11070103/v1
Metadata
- Authors
- Cassell, E. J.
- Affiliations
- Cornell University (US)
- Corresponding author
- Cassell, Eric J.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1999-10-05
- Volume
- 131
- Issue
- 7
- Pages
- 531-534
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2049646510
- Cited by
- 329
- References
- 13
- Citations by year
- 2026: 4 · 2025: 9 · 2024: 13 · 2023: 9 · 2022: 11 · 2021: 17 · 2020: 21 · 2019: 11 · 2018: 15 · 2017: 20 · 2016: 8 · 2015: 11 · 2014: 11 · 2013: 12 · 2012: 16
- FWCI
- 4.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Empathy and Medical Education
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Medicine, History, and Philosophy
- Health Sciences › Health Professions › General Health Professions › Patient-Provider Communication in Healthcare
- Keywords
- suffering, palliative care, dying patients, patient distress, physician-patient communication, empathic listening, subjective information, fear, meaning of symptoms, physician empathy, patient-centered care
- MeSH terms
- Clinical Competence, Humans, Pain, Physician-Patient Relations, Stress, Psychological, Terminally Ill, Pain Management
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