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Screening for Colorectal Cancer in Adults at Average Risk: A Summary of the Evidence for the U.S. Preventive Services Task Force
Abstract
PURPOSE: To assess the effectiveness of different colorectal cancer screening tests for adults at average risk. DATA SOURCES: Recent systematic reviews; Guide to Clinical Preventive Services, 2nd edition; and focused searches of MEDLINE from 1966 through September 2001. The authors also conducted hand searches, reviewed bibliographies, and consulted context experts to ensure completeness. STUDY SELECTION: When available, the most recent high-quality systematic review was used to identify relevant articles. This review was then supplemented with a MEDLINE search for more recent articles. DATA EXTRACTION: One reviewer abstracted information from the final set of studies into evidence tables, and a second reviewer checked the tables for accuracy. Discrepancies were resolved by consensus. DATA SYNTHESIS: For average-risk adults older than 50 years of age, evidence from multiple well-conducted randomized trials supported the effectiveness of fecal occult blood testing in reducing colorectal cancer incidence and mortality rates compared with no screening. Data from well-conducted case-control studies supported the effectiveness of sigmoidoscopy and possibly colonoscopy in reducing colon cancer incidence and mortality rates. A nonrandomized, controlled trial examining colorectal cancer mortality rates and randomized trials examining diagnostic yield supported the use of fecal occult blood testing plus sigmoidoscopy. The effectiveness of barium enema is unclear. Data are insufficient to support a definitive determination of the most effective screening strategy. CONCLUSIONS: Colorectal cancer screening reduces death from colorectal cancer and can decrease the incidence of disease through removal of adenomatous polyps. Several available screening options seem to be effective, but the single best screening approach cannot be determined because data are insufficient.
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“Strong direct and inferential evidence indicates that screening for colorectal cancer and adenomatous polyps reduces both mortality from and incidence of this disease.130,131”
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Cites
Prevention of Colorectal Cancer by Colonoscopic Polypectomy
Winawer, S. J., Zauber, A. G., Ho, M. N., O’Brien, M. J., Gottlieb, L. S., Sternberg, S. S., Waye, J. D., Schapiro, M., Bond, J. H., Panish, J. F., et al. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312303292701 · Cited by 4,585
Reducing Mortality from Colorectal Cancer by Screening for Fecal Occult Blood
Mandel, J. S., Bond, J. H., Church, T. R., Snover, D. C., Bradley, G. M., Schuman, L. M., & Ederer, F. (1993) · New England Journal of Medicine · doi:10.1056/nejm199305133281901 · Cited by 3,220
Randomised controlled trial of faecal-occult-blood screening for colorectal cancer
Hardcastle, J. D., Chamberlain, J., Robinson, M. H., Moss, S. M., Amar, S. S., Balfour, T. W., James, P., & Mangham, C. M. (1996) · The Lancet · doi:10.1016/s0140-6736(96)03386-7 · Cited by 2,784
Randomised study of screening for colorectal cancer with faecal-occult-blood test
Kronborg, O., Fenger, C., Olsen, J., Jørgensen, O. D., & Søndergaard, O. (1996) · The Lancet · doi:10.1016/s0140-6736(96)03430-7 · Cited by 2,495
Use of Colonoscopy to Screen Asymptomatic Adults for Colorectal Cancer
Lieberman, D. A., Weiss, D. G., Bond, J. H., Ahnen, D. J., Garewal, H. S., Harford, W. V., Provenzale, D., SONTAG, S., Schnell, T., Durbin, T. E., et al. (2000) · New England Journal of Medicine · doi:10.1056/nejm200007203430301 · Cited by 1,810
Current methods of the U.S. Preventive Services Task Force
Harris, R., Helfand, M., Woolf, S. H., Lohr, K. N., Mulrow, C. D., Teutsch, S. M., & Atkins, D. C. (2001) · American Journal of Preventive Medicine · doi:10.1016/s0749-3797(01)00261-6 · Cited by 1,720
Self-citationA Case–Control Study of Screening Sigmoidoscopy and Mortality from Colorectal Cancer
Selby, J. V., FRIEDMAN, G. D., Quesenberry, C. P., & Weiss, N. S. (1992) · New England Journal of Medicine · doi:10.1056/nejm199203053261001 · Cited by 1,700
Colorectal cancer screening: Clinical guidelines and rationale
Winawer, S. J., Fletcher, R. H., Miller, L. C., Godlee, F., Stolar, M. H., Mulrow, C. D., Woolf, S. H., Glick, S. N., Tg, G., Bond, J. H., et al. (1997) · Gastroenterology · doi:10.1053/gast.1997.v112.agast970594 · Cited by 1,605
Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies
Rex, D. K., Cutler, C., Lemmel, G. T., Rahmani, E. Y., Clark, D., Helper, D. J., Lehman, G. A., & Mark, D. G. (1997) · Gastroenterology · doi:10.1016/s0016-5085(97)70214-2 · Cited by 1,552
The Effect of Fecal Occult-Blood Screening on the Incidence of Colorectal Cancer
Mandel, J. S., Church, T. R., Bond, J. H., Ederer, F., Geisser, M. S., Mongin, S. J., Snover, D. C., & Schuman, L. M. (2000) · New England Journal of Medicine · doi:10.1056/nejm200011303432203 · Cited by 1,421
Imperiale, T. F., Wagner, D. R., Lin, C. Y., Larkin, G. N., Rogge, J. D., & Ransohoff, D. F. (2000) · New England Journal of Medicine · doi:10.1056/nejm200007203430302 · Cited by 1,056
Screening Sigmoidoscopy and Colorectal Cancer Mortality
Newcomb, P., Norfleet, R. G., Storer, B. E., et al. (1992) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/84.20.1572 · Cited by 924
Colorectal Cancer Mortality: Effectiveness of Biennial Screening for Fecal Occult Blood
Mandel, J. S., Church, T. R., Ederer, F., & Bond, J. H. (1999) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/91.5.434 · Cited by 788
Participation in Colorectal Cancer Screening: A Review
Vernon, S. W. (1997) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/89.19.1406 · Cited by 754
Flat and depressed colonic neoplasms: a prospective study of 1000 colonoscopies in the UK
Rembacken, B., Fujii, T., Cairns, A., Dixon, M., Yoshida, S., Chalmers, D. M., & Axon, A. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02086-9 · Cited by 659
Screening for Colorectal Cancer: Recommendation and Rationale
U.S. Preventive Services Task Force* (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-137-2-200207160-00014 · Cited by 598
A Comparison of Colonoscopy and Double-Contrast Barium Enema for Surveillance after Polypectomy
Winawer, S. J., Stewart, E. T., Zauber, A. G., Bond, J. H., Ansel, H. J., Waye, J. D., Hall, D., Hamlin, J. A., Schapiro, M., O’Brien, M. J., et al. (2000) · New England Journal of Medicine · doi:10.1056/nejm200006153422401 · Cited by 582
Rex, D. K., Rahmani, E. Y., Haseman, J., Lemmel, G. T., Kaster, S., & Buckley, J. (1997) · Gastroenterology · doi:10.1016/s0016-5085(97)70213-0 · Cited by 576
Thiis-Evensen, E. (1999) · Scandinavian Journal of Gastroenterology · doi:10.1080/003655299750026443 · Cited by 466
Macrae, F., Tan, K. G., & Williams, C. B. (1983) · Gut · doi:10.1136/gut.24.5.376 · Cited by 429
Endoscopic Perforation of The Colon: Lessons From A 10-Year Study
Anderson, M. L., Pasha, T. M., & Leighton, J. A. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.03356.x · Cited by 409
Protection by Endoscopy Against Death From Colorectal Cancer
Müller, A. (1995) · Archives of Internal Medicine · doi:10.1001/archinte.1995.00430160065007 · Cited by 392
Improving Preventive Care by Prompting Physicians
Balas, E. A. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.3.301 · Cited by 385
Screening for Colorectal Cancer With Fecal Occult Blood Testing and Sigmoidoscopy
Winawer, S. J., Flehinger, B. J., Schottenfeld, D., & Miller, D. G. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.16.1311 · Cited by 379
Rex, D. K., Johnson, D. A., Lieberman, D. A., Burt, R. W., & Sonnenberg, A. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.02059.x · Cited by 238
Hemorrhage following colonoscopic polypectomy
Rosen, L., Bub, D. S., REED, J. F., et al. (1993) · Diseases of the Colon & Rectum · doi:10.1007/bf02052261 · Cited by 228
Ransohoff, D. F., & Lang, C. A. (1997) · Annals of Internal Medicine · doi:10.7326/0003-4819-126-10-199705150-00014 · Cited by 213
Going the Distance — The Case for True Colorectal-Cancer Screening
Podolsky, D. K. (2000) · New England Journal of Medicine · doi:10.1056/nejm200007203430309 · Cited by 170
Complications and adverse effects of colonoscopy with selective sedation
Eckardt, V. F., Kanzler, G., Schmitt, T., et al. (1999) · Gastrointestinal Endoscopy · doi:10.1016/s0016-5107(99)70382-2 · Cited by 169
Prospective analysis of complications 30 days after outpatient colonoscopy
Zubarik, R. S., Fleischer, D. E., Mastropietro, C., et al. (1999) · Gastrointestinal Endoscopy · doi:10.1053/ge.1999.v50.97111 · Cited by 167
Kramer, B. S., Gohagan, J. K., Prorok, P. C., et al. (2010) · Cancer · doi:10.1002/cncr.2820710215 · Cited by 143
Complications of barium enema examinations: A survey of UK consultant radiologists 1992 to 1994
Blakeborough, A., Sheridan, M. B., & Chapman, A. H. (1997) · Clinical Radiology · doi:10.1016/s0009-9260(97)80108-0 · Cited by 140
Uptake, yield of neoplasia, and adverse effects of flexible sigmoidoscopy screening
Atkin, W. S., Hart, A. R., Edwards, R. P., McIntyre, P., Aubrey, R., Wardle, J., Sutton, S. R., Cuzick, J. M., & Northover, J. M. A. (1998) · Gut · doi:10.1136/gut.42.4.560 · Cited by 138
Postpolypectomy colonic hemorrhage
Gibbs, D. H., Opelka, F. G., Beck, D. E., et al. (1996) · Diseases of the Colon & Rectum · doi:10.1007/bf02054448 · Cited by 137
Management of Colonoscopic Perforations
Farley, D. R., Bannon, M. P., Zietlow, S. P., et al. (1997) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(11)63592-1 · Cited by 134
The Best Screening Test for Colorectal Cancer — A Personal Choice
Woolf, S. H. (2000) · New England Journal of Medicine · doi:10.1056/nejm200011303432211 · Cited by 128
Experience with 1000 Colonoscopic Polypectomies
Webb, W. A., McDaniel, L., & JONES, L. C. (1985) · Annals of Surgery · doi:10.1097/00000658-198505000-00012 · Cited by 101
Rasmussen, M. S. (1999) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365529950172862 · Cited by 100
Cost-effectiveness of double-contrast barium enema in screening for colorectal cancer.
Glick, S. N., Wagner, J. L., & Johnson, C. D. (1998) · American Journal of Roentgenology · doi:10.2214/ajr.170.3.9490943 · Cited by 95
Selective management of colonoscopic perforations.
Lo, A. Y., & Beaton, H. L. (1994) · PubMed · Cited by 94
Verne, J., Aubrey, R., Love, S., et al. (1998) · BMJ · doi:10.1136/bmj.317.7152.182 · Cited by 93
Berry, D. P., Clarke, P. A., Hardcastle, J. D., et al. (1997) · British journal of surgery · doi:10.1046/j.1365-2168.1997.02759.x · Cited by 92
Iatrogenic perforation of the colon and rectum
Nelson, R. L., Abcarian, H., & Prasad, L. M. (1982) · Diseases of the Colon & Rectum · doi:10.1007/bf02553602 · Cited by 90
Barium enemas of carcinoma of the colon: sensitivity of double- and single-contrast studies
Johnson, C., Carlson, H. C., Taylor, W., et al. (1983) · American Journal of Roentgenology · doi:10.2214/ajr.140.6.1143 · Cited by 84
Brady, A. P., Stevenson, G. W., & Stevenson, I. (1994) · Radiology · doi:10.1148/radiology.192.2.8029400 · Cited by 82
Complications in colonoscopic polypectomy: lessons to learn from an experience with 1576 polyps.
Nivatvongs, S. (1988) · PubMed · Cited by 82
Ure, T., Dehghan, K., Vernava, A. M., et al. (1995) · Surgical Endoscopy · doi:10.1007/bf00206836 · Cited by 71
How well can surgeons perform colonoscopy?
Wexner, S. D., Forde, K. A., Sellers, G. J., et al. (1998) · Surgical Endoscopy · doi:10.1007/s004649900870 · Cited by 64
Endoscopic and surgical complications of work-up in screening for colorectal cancer
Kewenter, J., & Brevinge, H. (1996) · Diseases of the Colon & Rectum · doi:10.1007/bf02056949 · Cited by 63
The Findings and Impact of Nonrehydrated Guaiac Examination of the Rectum (FINGER) Study
Bini, E. J., Rajapaksa, R. C., & Weinshel, E. H. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.17.2022 · Cited by 52
Age as a risk factor in colonoscopy: fact versus fiction.
DiPrima, R. E., Barkin, J. S., Blinder, M., et al. (1988) · PubMed · Cited by 50
Barium enema examination: sensitivity in detecting colonic polyps and carcinomas.
Ott, D. J., Scharling, E. S., Chen, Y. M., et al. (1989) · PubMed · Cited by 38
Yamamoto, M., & Nakama, H. (2000) · PubMed · Cited by 36
Strøm, E., & Larsen, J. L. (1999) · Radiology · doi:10.1148/radiology.211.1.r99ap37211 · Cited by 33
Herrinton, L. J., Selby, J. V., FRIEDMAN, G. D., et al. (1995) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a117744 · Cited by 31
Eisner, M. S. (1991) · Archives of Internal Medicine · doi:10.1001/archinte.151.11.2180 · Cited by 27
Ott, D. J., Scharling, E. S., Chen, Y. M., et al. (1989) · Southern Medical Journal · doi:10.1097/00007611-198902000-00013 · Cited by 27
Endoscopic cecal perforation: mechanisms of injury.
Foliente, R. L., Chang, A., Youssef, A., et al. (1996) · PubMed · Cited by 26
Unplanned Work Absence Following Outpatient Colonoscopy
Newcomer, M. K., Shaw, M. J., Williams, D. M., et al. (1999) · Journal of Clinical Gastroenterology · doi:10.1097/00004836-199907000-00019 · Cited by 22
Perforations from colonoscopy during diagnosis and treatment of polyps.
Brynitz, S., Kjaergård, H. K., & Struckmann, J. (1986) · PubMed · Cited by 22
RELIABILITY OF BARIUM ENEMA IN DETECTING COLONIC NEOPLASIA
Bloomfield, J. A. (1981) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1981.tb135891.x · Cited by 22
The fluoroscopic barium enema in colonic polyp detection
Teefey, S., & Carlson, H. C. (1983) · American Journal of Roentgenology · doi:10.2214/ajr.141.6.1279 · Cited by 20
Myllylä, V. V., Päivänsalo, M. J., & Laitinen, S. T. (1984) · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · doi:10.1055/s-2008-1052995 · Cited by 10
Diagnostic sensitivity of x-ray examination of the large bowel in colorectal cancer
Brekkan, Á., Kjartansson, Ó., Tulinius, H., et al. (1983) · Abdominal Imaging · doi:10.1007/bf01948152 · Cited by 9
Research works printed but not linked: 9
- Yamamoto M, 2000, Hepatogastroenterology, 47, 396
- 10.1001/archinte.1991.00400110044009 · DOI
- Berry DP, 1997, Br J Surg, 84, 1274
- Foliente RL, 1996, Am J Gastroenterol, 91, 705
- Lo AY, 1994, J Am Coll Surg, 179, 333
- DiPrima RE, 1988, Am J Gastroenterol, 83, 123
- Nivatvongs S, 1988, Am Surg, 54, 61
- Brynitz S, 1986, Ann Chir Gynaecol, 75, 142
- Rex DK, 2000, Am J Gastroenterol, 95, 868
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Prevalence of major risk factors and use of screening tests for cancer in the United States
Fedewa, S. A., Sauer, A. G., Siegel, R. L., & Jemal, A. (2015) · Cancer Epidemiology, Biomarkers & Prevention · doi:10.1158/1055-9965.epi-15-0134 · Cited by 77
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Metadata
- Authors
- Pignone, M., Rich, M., Teutsch, S. M., Berg, A. O., & Lohr, K. N.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 2002-07-16
- Volume
- 137
- Issue
- 2
- Pages
- 132-141
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2072878220
- Cited by
- 741
- References
- 64
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 6 · 2023: 8 · 2022: 6 · 2021: 7 · 2020: 7 · 2019: 8 · 2018: 10 · 2017: 13 · 2016: 15 · 2015: 28 · 2014: 36 · 2013: 24 · 2012: 33
- FWCI
- 5.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (290-97-0011)
- Topics
- Health Sciences › Medicine › Oncology › Colorectal Cancer Screening and Detection
- Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
- Health Sciences › Medicine › Oncology › Colorectal Cancer Surgical Treatments
- Keywords
- colorectal cancer screening, average-risk population, fecal occult blood test, sigmoidoscopy, colonoscopy, barium enema, colorectal cancer mortality, adenomatous polyps, colorectal cancer incidence, screening effectiveness
- MeSH terms
- Age Factors, Colonoscopy, Enema, Female, Humans, Male, Mass Screening, Middle Aged, Occult Blood, Physical Examination, Rectum, Sigmoidoscopy, Time Factors, Colorectal Neoplasms, Evidence-Based Medicine
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