The DOI matches its Crossref record.
A Controlled Study of the Prophylactic Portacaval Shunt: A Final Report
Abstract
Ninety-three patients with cirrhosis and esophageal varices participated in a controlled prospective investigation of the prophylactic portacaval shunt procedure for the prevention of bleeding varices. Surgery sharply reduced the risk of esophageal bleeding but failed to improve longevity. Shunted patients have a greater prevalence of hepatocellular failure and are significantly more likely to develop hepatic encephalopathy. Abstinence from alcohol had a beneficial effect in preventing bleeding varices and ascites in unshunted patients but did not significantly improve mortality; continued drinking among surgical patients did not alter any of these variables. Attempts to estimate survival or to delineate clinical factors at selection leading to variceal hemorrhage were unsuccessful. In the management of cirrhosis of the alcoholic in lower socioeconomic groups the prophylactic portacaval shunt should be abandoned.
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Citations
Cited by
The treatment of portal hypertension: A meta-analytic review
D'amico, G., Pagliaro, L., & Bosch, J. (1995) · Hepatology · doi:10.1002/hep.1840220145 · Cited by 1,015
Randomized versus historical controls for clinical trials
Sacks, H., Chalmers, T. C., & Smith, H. (1982) · The American Journal of Medicine · doi:10.1016/0002-9343(82)90815-4 · Cited by 834
Self-citationThe Prophylactic Portacaval Shunt
(1972) · The Lancet · doi:10.1016/s0140-6736(72)91163-4 · Cited by 373
Gores, G. J., Wiesner, R. H., Dickson, E. R., Zinsmeister, A. R., Jorgensen, R. A., & Langworthy, A. (1989) · Gastroenterology · doi:10.1016/0016-5085(89)90526-x · Cited by 173
Metadata
- Authors
- RESNICK, R. H., CHALMERS, T. C., ISHIHARA, A. M., GARCEAU, A. J., CALLOW, A. D., SCHIMMEL, E. M., O'HARA, E. T., & BOSTON INTER-HOSPITAL LIVER GROUP
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1969-04-01
- Volume
- 70
- Issue
- 4
- Pages
- 675-688
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W1967522559
- Cited by
- 237
- References
- 0
- FWCI
- 20.54
- Type
- journal article
- Language
- en
- Open access
- closed
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- RESNICK, R. H., CHALMERS, T. C., ISHIHARA, A. M., GARCEAU, A. J., CALLOW, A. D., SCHIMMEL, E. M., O'HARA, E. T., & BOSTON INTER-HOSPITAL LIVER GROUP. (1969). A Controlled Study of the Prophylactic Portacaval Shunt: A Final Report. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-70-4-675
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
