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Pleural Effusions: The Diagnostic Separation of Transudates and Exudates
Abstract
In this prospective study of 150 pleural effusions, the utility of pleural-fluid cell counts, protein levels, and lactic dehydrogenase (LDH) levels for the separation of transudates from exudates was evaluated. According to preset diagnostic criteria, 47 of the effusions were classified as transudates and 103 as exudates. Three characteristics were found, each of which was associated with over 70% of the exudates and, at most, one of the transudates: [1] a pleural fluid-to-serum protein ratio greater than 0.5; [2] a pleural fluid LDH greater than 200 IU; and [3] a pleural fluid-to-serum LDH ratio greater than 0.6. Moreover, all but one exudate had at least one of these three characteristics, whereas only one transudate had any of the three. The simultaneous use of both the pleural-fluid protein and LDH levels better differentiates transudates from exudates than does the use of either of these values individually.
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Cited by
Seibert, A. F., Haynes, J., Middleton, R., & Bass, J. B. (1991) · Chest · doi:10.1378/chest.99.4.883 · Cited by 320
Yield of sputum induction in the diagnosis of pleural tuberculosis
Conde, M. B., Loivos, A. C., Rezende, V. M., Soares, S. L. M., Mello, F. C. Q., Reingold, A. L., Daley, C. L., & Kritski, A. L. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2111019 · Cited by 204
Langridge, T. D., & Gemeinhart, R. A. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.12.038 · Cited by 51
Supersparse Linear Integer Models for Interpretable Classification
Ustun, B., Tracà, S., & Rudin, C. (2013) · arXiv · doi:10.48550/arxiv.1306.6677 · Cited by 26
Metadata
- Authors
- LIGHT, R. W., MACGREGOR, M. I., LUCHSINGER, P. C., & BALL, W. C.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1972-10-01
- Volume
- 77
- Issue
- 4
- Pages
- 507-513
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2082563075
- Cited by
- 1,780
- References
- 0
- FWCI
- 4.84
- Type
- journal article
- Language
- en
- Open access
- closed
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- LIGHT, R. W., MACGREGOR, M. I., LUCHSINGER, P. C., & BALL, W. C. (1972). Pleural Effusions: The Diagnostic Separation of Transudates and Exudates. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-77-4-507
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