The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Nosocomial Respiratory Infections with Gram-Negative Bacilli: The Significance of Colonization of the Respiratory Tract
Abstract
A prospective study of 213 patients admitted to a medical intensive care unit was done to determine the frequency of colonization of the respiratory tract with Gram-negative bacilli and the relation of such colonization to nosocomial infection. Ninety-five patients (45%) became colonized, 22% on the first hospital day. Associated with colonization were respiratory tract disease, coma, hypotension, tracheal intubation, acidosis, azotemia, and either leukocytosis or leukopenia. Antimicrobial therapy may have promoted colonization in some patients. Nosocomial infections developed in 26 patients (12.2%), 22 of whom were colonized with Gram-negative bacilli. Nosocomial respiratory infections occurred in 23% of colonized patients but in only 3.3% of noncolonized patients. The control of nosocomial pneumonia may require the development of methods for preventing or interrupting the colonization of hospitalized patients with Gram-negative bacilli.
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Citations
Cites
Changing Pharyngeal Bacterial Flora of Hospitalized Patients: Emergence of Gram-Negative Bacilli
Johanson, W. G., Pierce, A. K., & Sanford, J. P. (1969) · New England Journal of Medicine · doi:10.1056/nejm196911202812101 · Cited by 910
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Cited by
Torres, A., Serra-Batlles, J., Ros, E., Piera, C., de la Bellacasa, J. P., Cobos, A., Lomeña, F., & Rodríguez-Roisin, R. (1992) · Annals of Internal Medicine · doi:10.7326/0003-4819-116-7-540 · Cited by 721
Meduri, G. U., Mauldin, G. L., Wunderink, R. G., Leeper, K. V., Jones, C. B., Tolley, E., & Mayhall, G. (1994) · Chest · doi:10.1378/chest.106.1.221 · Cited by 339
Saliva-Bacterium Interactions in Oral Microbial Ecology
Scannapieco, F. A. (1994) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411940050030201 · Cited by 328
Aspiration pneumonia: A review of modern trends
DiBardino, D. M., & Wunderink, R. G. (2015) · Journal of Critical Care · doi:10.1016/j.jcrc.2014.07.011 · Cited by 305
Does This Patient Have Ventilator-Associated Pneumonia?
Klompas, M. (2007) · JAMA · doi:10.1001/jama.297.14.1583 · Cited by 304
Metadata
- Authors
- JOHANSON, W. G., PIERCE, A. K., SANFORD, J. P., & THOMAS, G. D.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1972-11-01
- Volume
- 77
- Issue
- 5
- Pages
- 701-706
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2024888235
- Cited by
- 1,087
- References
- 1
- FWCI
- 18.56
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Nosocomial Respiratory Infections with Gram-Negative Bacilli: The Significance of Colonization of the Respiratory Tract. https://app.cochat.ai/papers/10.7326/0003-4819-77-5-701
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- JOHANSON, W. G., PIERCE, A. K., SANFORD, J. P., & THOMAS, G. D. (1972). Nosocomial Respiratory Infections with Gram-Negative Bacilli: The Significance of Colonization of the Respiratory Tract. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-77-5-701
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
