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Infection Control in Intravenous Therapy
Abstract
The intravenous infusion has become indispensable in modern medical therapy, but infection, especially infusion-associated septicemia, remains a life-threatening hazard. In 1970 to 1971 a nationwide epidemic of nosocomial Gram-negative septicemia, traced by the Center for Disease Control to one supplier's contaminated infusion products, dramatically focused attention on the problem of infusion-related infection. Contamination of the intravenous system can occur at virtually any point, from the time of manufacture until the infusion is terminated in the hospital. Once contaminated, the intravenous cannula and its adherent thrombus can serve as an intravascular nidus for the proliferation and dissemination of microorganisms. Some pathogens grow luxuriantly in infusion fluids at room temperature, attaining concentrations exceeding 105 organisms per millilitre in 24 hours. Moreover, contamination of infusion fluid in use is probably common and must now be recognized as a potential cause of septicemia.
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Cited by
Guidelines for the Prevention of Intravascular Catheter-related Infections
O'Grady, N. P., Alexander, M., Burns, L. A., Dellinger, E. P., Garland, J., Heard, S. O., Lipsett, P. A., Masur, H., Mermel, L. A., Pearson, M. L., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir257 · Cited by 4,699
Loveday, H. P., Wilson, J. A., Pratt, R. J., Golsorkhi, M., Tingle, A., Bak, A., Browne, J., Prieto, J., & Wilcox, M. (2014) · Journal of Hospital Infection · doi:10.1016/s0195-6701(13)60012-2 · Cited by 1,621
Guidelines for the prevention of intravascular catheter-related infections
O'Grady, N. P., Alexander, M., Burns, L. A., Dellinger, E. P., Garland, J., Heard, S. O., Lipsett, P. A., Masur, H., Mermel, L. A., Pearson, M. L., et al. (2011) · American Journal of Infection Control · doi:10.1016/j.ajic.2011.01.003 · Cited by 1,066
Guidelines for the Prevention of Intravascular Catheter–Related Infections
O’Grady, N. P., Alexander, M., Dellinger, E. P., Gerberding, J. L., Heard, S. O., Maki, D. G., Masur, H., McCormick, R. D., Mermel, L. A., Pearson, M. L., et al. (2002) · Infection Control and Hospital Epidemiology · doi:10.1086/502007 · Cited by 847
Self-citationO'Grady, N. P., Alexander, M., Burns, L. A., Dellinger, E. P., Garland, J., Heard, S. O., Lipsett, P. A., Masur, H., Mermel, L. A., Pearson, M. L., et al. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir138 · Cited by 560
Metadata
- Authors
- MAKI, D. G., GOLDMNAN, D. A., & RHAME, F. S.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1973-12-01
- Volume
- 79
- Issue
- 6
- Pages
- 867-887
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2010421195
- Cited by
- 536
- References
- 0
- FWCI
- 33.68
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Infection Control in Intravenous Therapy. https://app.cochat.ai/papers/10.7326/0003-4819-79-6-867
- The paper
- MAKI, D. G., GOLDMNAN, D. A., & RHAME, F. S. (1973). Infection Control in Intravenous Therapy. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-79-6-867
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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