Electrophysiologic Evaluation of Elderly Patients with Sinus Bradycardia: A Long-Term Follow-Up Study
Abstract
One hundred three patients with persistent sinus bradycardia were evaluated electrophysiologically and followed prospectively for a mean of 4.6 years. The 5-year survival rate was 74.8%, not significantly different from the 72% rate in the general population with similar age and sex distribution. Forty-one patients had abnormal corrected sinus-node recovery time. Overall accuracy of abnormal corrected sinus-node recovery time in predicting serious sinus node disease in symptomatic and asymptomatic patients was 90% (37 of 41 patients) and 100% in patients with syncope (18 of 18 patients). The sensitivity of the test was 66%. Abnormal corrected sinus-node recovery time in patients with sinus bradycardia appears to be a valuable specific, predictive index of serious sinus node disease and therefore a useful test in selecting patients for pacemaker therapy, especially if symptoms such as dizziness or syncope are present.
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One observational study showed a relationship between the presence of prolonged SNRT at EPS and the effect of pacing on symptoms.
“Oneobservational study showed a relationship between the presence of prolonged SNRT at EPS and the effect of pacing on symptoms. 211”
From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [211]
An abnormal SNRT enhances the probability of efficacy of cardiac pacing.
“An abnormal SNRT enhances the probability of efficacy of cardiac pacing (see section 4.2.6.1). 210-212”
From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [211]
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References 23 · Cited by 158
- Authors
- GANN, D., TOLENTINO, A., & SAMET, P.
- Affiliations
- Mount Sinai Medical Center (US)
- Miami Beach and Coral Gables, Florida
- Corresponding author
- GANN, DIETMAR
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1979-01-01
- Volume
- 90
- Issue
- 1
- Pages
- 24-29
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2038135158
- Cited by
- 158
- References
- 23
- Citations by year
- 2026: 1 · 2024: 1 · 2023: 2 · 2022: 4 · 2021: 6 · 2020: 4 · 2019: 2 · 2018: 6 · 2017: 1 · 2016: 2 · 2014: 1 · 2013: 2 · 2012: 1
- FWCI
- 6.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Keywords
- sinus bradycardia, sinus node recovery time, sinus node disease, syncope, pacemaker therapy, elderly patients, survival, diagnostic accuracy, electrophysiologic testing
- MeSH terms
- Aged, Bradycardia, Female, Florida, Follow-Up Studies, Humans, Male, Middle Aged, Pacemaker, Artificial, Prospective Studies, Sinoatrial Node, Time Factors
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