Generalized Anxiety Disorder
Abstract
Generalized anxiety disorder (GAD) is a common and disabling illness that is often underdiagnosed and undertreated. Patients with GAD are at increased risk for suicide as well as cardiovascular-related events and death. Most patients can be diagnosed and managed by primary care physicians. Symptoms include chronic, pervasive anxiety and worry accompanied by nonspecific physical and psychological symptoms (restlessness, fatigue, difficulty concentrating, irritability, muscle tension, or sleep disturbances). Effective treatments include psychotherapy (often cognitive behavioral therapy) and pharmacotherapy, such as selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors.
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GAD often goes undetected and thus untreated in primary health care patients.
“Previous research shows that GAD often goes undetected and thus untreated in primary health care patients [6, 8, 11, 12, 16].”
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References 68 · Cited by 226
- Authors
- DeMartini, J., Patel, G., & Fancher, T. L.
- Affiliations
- University of California, Davis (US)
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 2019-04-02
- Volume
- 170
- Issue
- 7
- Pages
- ITC49-ITC64
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2064282706
- Cited by
- 226
- References
- 68
- Citations by year
- 2026: 29 · 2025: 41 · 2024: 54 · 2023: 48 · 2022: 34 · 2021: 13 · 2020: 4 · 2019: 2 · 2014: 1
- FWCI
- 2.05
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Disorders
- Keywords
- generalized anxiety disorder, underdiagnosis, suicide risk, cardiovascular risk, primary care management, chronic worry, somatic symptoms, psychotherapy, cognitive behavioral therapy, selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors, pharmacotherapy
- MeSH terms
- Serotonin and Noradrenaline Reuptake Inhibitors, Anxiety Disorders, Humans, Patient Education as Topic, Psychotherapy, Quality of Health Care, Referral and Consultation, Risk Factors, United States, Selective Serotonin Reuptake Inhibitors, Practice Guidelines as Topic, Antidepressive Agents, Second-Generation
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