The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Risk for Hospitalized Heart Failure Among New Users of Saxagliptin, Sitagliptin, and Other Antihyperglycemic Drugs: A Retrospective Cohort Study
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Saxagliptin has raised concerns regarding potential increased risks of heart failure.
“This contrasts with saxagliptin, another dipeptidyl peptidase-4 inhibitor, which has raised concerns regarding potential increased risks of heart failure, and linagliptin, which is commonly prescribed for patients with kidney impairment, and thus could lead to increased confounding in contrast to our comparator sitagliptin.20-25”
From Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction (2025) · cites this paper as [23]
Linagliptin is commonly prescribed for patients with kidney impairment, which could lead to increased confounding in contrast to sitagliptin.
“This contrasts with saxagliptin, another dipeptidyl peptidase-4 inhibitor, which has raised concerns regarding potential increased risks of heart failure, and linagliptin, which is commonly prescribed for patients with kidney impairment, and thus could lead to increased confounding in contrast to our comparator sitagliptin.20-25”
From Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction (2025) · cites this paper as [23]
The Discussion mentions linagliptin only when reporting a heart-failure odds ratio from a meta-analysis; it does not discuss prescribing linagliptin to patients with kidney impairment. Although the Abstract lists residual confounding as a limitation, our copy does not link it to linagliptin or compare it with sitagliptin on that basis (searched: linagliptin, kidney impairment, renal prescribing, confounding). (LLM, conf=0.76)
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Cites
Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes
Green, J. B., Bethel, M. A., Armstrong, P. W., Buse, J. B., Engel, S. S., Garg, J., Josse, R., Kaufman, K. D., Koglin, J., Korn, S., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1501352 · Cited by 2,577
Scirica, B. M., Braunwald, E., Raz, I., Cavender, M. A., Morrow, D. A., Jarolim, P., Udell, J. A., Mosenzon, O., Im, K., Umez-Eronini, A. A., et al. (2014) · Circulation · doi:10.1161/circulationaha.114.010389 · Cited by 725
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Cited by
Sorted by citations
Nauck, M. A., Meier, J. J., Cavender, M. A., Abd El Aziz, M., & Drucker, D. J. (2017) · Circulation · doi:10.1161/circulationaha.117.028136 · Cited by 582
Diabetes Mellitus and Heart Failure
Lehrke, M., & Marx, N. (2017) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2017.05.014 · Cited by 236
Azoulay, L., & Suissa, S. (2017) · Diabetes Care · doi:10.2337/dc16-1943 · Cited by 195
Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction
Krüger, N., Schneeweiss, S., Fuse, K., Matseyko, S., Sreedhara, S. K., Hahn, G., Schunkert, H., & Wang, S. V. (2025) · JAMA · doi:10.1001/jama.2025.14092 · Cited by 66
Metadata
- Authors
- Toh, S., Hampp, C., Reichman, M. E., Graham, D. J., Balakrishnan, S., Pucino, F., Hamilton, J., Lendle, S., Iyer, A., Rucker, M., Pimentel, M., Nathwani, N., Griffin, M. R., Brown, N. J., & Fireman, B. H.
- Affiliations
- From Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts; U.S. Food and Drug Administration, Silver Spring, Maryland; Vanderbilt University and VA Tennessee Valley Health Care System, Nashville, Tennessee; and Kaiser Permanente Northern California, Oakland, California.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 2016-06-07
- Volume
- 164
- Issue
- 11
- Pages
- 705-714
- ISSN
- 0003-4819
- 1539-3704
- PMC
- PMC5178978
- Cited by
- 91
- References
- 2
- Language
- en
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