The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors
Open accessAbstract
Reactive oxygen species (ROS)-dependent signaling pathways from chloroplasts and mitochondria merge at the nuclear protein RADICAL-INDUCED CELL DEATH1 (RCD1). RCD1 interacts in vivo and suppresses the activity of the transcription factors ANAC013 and ANAC017, which mediate a ROS-related retrograde signal originating from mitochondrial complex III. Inactivation of RCD1 leads to increased expression of mitochondrial dysfunction stimulon (MDS) genes regulated by ANAC013 and ANAC017. Accumulating MDS gene products, including alternative oxidases (AOXs), affect redox status of the chloroplasts, leading to changes in chloroplast ROS processing and increased protection of photosynthetic apparatus. ROS alter the abundance, thiol redox state and oligomerization of the RCD1 protein in vivo, providing feedback control on its function. RCD1-dependent regulation is linked to chloroplast signaling by 3'-phosphoadenosine 5'-phosphate (PAP). Thus, RCD1 integrates organellar signaling from chloroplasts and mitochondria to establish transcriptional control over the metabolic processes in both organelles.
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The Amber biomolecular simulation programs
Case, D. A., Cheatham, T. E., Darden, T., Gohlke, H., Luo, R., Merz, K. M., Onufriev, A., Simmerling, C., Wang, B., & Woods, R. J. (2005) · Journal of Computational Chemistry · doi:10.1002/jcc.20290 · Cited by 9,535
Gibon, Y., Blaesing, O. E., Hannemann, J., Carillo, P., Höhne, M., Hendriks, J. H. M., Palacios, N., Cross, J., Selbig, J., & Stitt, M. (2004) · The Plant Cell · doi:10.1105/tpc.104.025973 · Cited by 552
König, J., Baier, M., Horling, F., Kahmann, U., Harris, G., Schürmann, P., & Dietz, K.-J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.072644999 · Cited by 301
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The integration of reactive oxygen species (ROS) and calcium signalling in abiotic stress responses
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Metadata
- Authors
- Shapiguzov, A., Vainonen, J. P., Hunter, K., Tossavainen, H., Tiwari, A., Järvi, S., Hellman, M., Aarabi, F., Alseekh, S., Wybouw, B., Van Der Kelen, K., Nikkanen, L., Krasensky-Wrzaczek, J., Sipari, N., Keinänen, M., Tyystjärvi, E., Rintamäki, E., De Rybel, B., Salojärvi, J., Van Breusegem, F., Fernie, A. R., Brosché, M., Permi, P., Aro, E.-M., Wrzaczek, M., & Kangasjärvi, J.
- Venue
- eLife
- Publisher
- eLife Sciences Publications, Ltd
- Published
- 2019-02-15
- Volume
- 8
- ISSN
- 2050-084X (ISSN-L)
- OpenAlex
- W2914362360
- Cited by
- 174
- References
- 3
- FWCI
- 6.52
- Type
- journal article
- Language
- en
- Open access
- gold
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- Shapiguzov, A., Vainonen, J. P., Hunter, K., Tossavainen, H., Tiwari, A., Järvi, S., Hellman, M., Aarabi, F., Alseekh, S., Wybouw, B., Van Der Kelen, K., Nikkanen, L., Krasensky-Wrzaczek, J., Sipari, N., Keinänen, M., Tyystjärvi, E., Rintamäki, E., De Rybel, B., Salojärvi, J., . . . Kangasjärvi, J. (2019). Arabidopsis RCD1 coordinates chloroplast and mitochondrial functions through interaction with ANAC transcription factors. eLife. https://doi.org/10.7554/elife.43284
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
