CoChat
Sign Up
Cited by 12Glycosylation and Glycoproteins ResearchCarbohydrate Chemistry and SynthesisFungal and yeast genetics research

The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.

Agl24 is an ancient archaeal homolog of the eukaryotic N-glycan chitobiose synthesis enzymes

Open access
Meyer, Benjamin H, Adam, Panagiotis S, Wagstaff, Ben A, Kolyfetis, George E, Probst, Alexander J, Albers, Sonja V, Dorfmueller, Helge C·2022·eLife
DOI 10.7554/elife.67448PMC PMC8993221

Published version of a preprint

Open this paper in CoChat — free account

Abstract

Protein N-glycosylation is a post-translational modification found in organisms of all domains of life. The crenarchaeal N-glycosylation begins with the synthesis of a lipid-linked chitobiose core structure, identical to that in Eukaryotes, although the enzyme catalyzing this reaction remains unknown. Here, we report the identification of a thermostable archaeal β-1,4- N -acetylglucosaminyltransferase, named a rchaeal gl ycosylation enzyme 24 (Agl24), responsible for the synthesis of the N-glycan chitobiose core. Biochemical characterization confirmed its function as an inverting β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol glycosyltransferase. Substitution of a conserved histidine residue, found also in the eukaryotic and bacterial homologs, demonstrated its functional importance for Agl24. Furthermore, bioinformatics and structural modeling revealed similarities of Agl24 to the eukaryotic Alg14/13 and a distant relation to the bacterial MurG, which are catalyzing the same or a similar reaction, respectively. Phylogenetic analysis of Alg14/13 homologs indicates that they are ancient in Eukaryotes, either as a lateral transfer or inherited through eukaryogenesis.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.7554/elife.67448

Cites

5 of 5 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 110

  1. Abu-Qarn, 2007, Haloferax volcanii AglB and AglD are involved in N-glycosylation of the S-layer glycoprotein and proper assembly of the surface layer, Journal of Molecular Biology, 374, 1224, 10.1016/j.jmb.2007.10.042 · DOI
  2. Adam, 2021, Genomic Remnants of Ancestral Hydrogen and Methane Metabolism in Archaea Drive Anaerobic Carbon Cycling, 10.1101/2021.08.02.454722 · DOI
  3. Akıl, 2018, Genomes of Asgard archaea encode profilins that regulate actin, Nature, 562, 439, 10.1038/s41586-018-0548-6 · DOI
  4. Akıl, 2020, Insights into the evolution of regulated actin dynamics via characterization of primitive gelsolin/cofilin proteins from Asgard archaea, PNAS, 117, 19904, 10.1073/pnas.2009167117 · DOI
  5. Albers, 2017, Essentials of Glycobiology Archaea
  6. Apweiler, 1999, On the frequency of protein glycosylation, as deduced from analysis of the SWISS-PROT database, Biochimica et Biophysica Acta, 1473, 4, 10.1016/s0304-4165(99)00165-8 · DOI
  7. Averbeck, 2007, Membrane topology of the Alg14 endoplasmic reticulum UDP-GlcNAc transferase subunit, The Journal of Biological Chemistry, 282, 29081, 10.1074/jbc.M704410200 · DOI
  8. Baker, 1992, Structural consequences of sequence patterns in the fingerprint region of the nucleotide binding fold, Journal of Molecular Biology, 228, 662, 10.1016/0022-2836(92)90848-e · DOI
  9. Baum, 2014, An inside-out origin for the eukaryotic cell, BMC Biology, 12, 10.1186/s12915-014-0076-2 · DOI
  10. Bickel, 2005, Biosynthesis of lipid-linked oligosaccharides in Saccharomyces cerevisiae: Alg13p and Alg14p form a complex required for the formation of GlcNAc(2)-PP-dolichol, The Journal of Biological Chemistry, 280, 34500, 10.1074/jbc.M506358200 · DOI
  11. Boratyn, 2012, Domain enhanced lookup time accelerated BLAST, Biology Direct, 7, 10.1186/1745-6150-7-12 · DOI
  12. Bouhss, 2008, The biosynthesis of peptidoglycan lipid-linked intermediates, FEMS Microbiology Reviews, 32, 208, 10.1111/j.1574-6976.2007.00089.x · DOI
  13. Brock, 1972, Sulfolobus - new genus of sulfur-oxidizing bacteria living at low pH and high temperature, Archiv Fur Mikrobiologie, 84, 54, 10.1007/BF00408082 · DOI
  14. Brown, 2013, Crystal structure of the Pseudomonas aeruginosa MurG: UDP-GlcNAc substrate complex, Protein and Peptide Letters, 20, 1002, 10.2174/0929866511320090006 · DOI
  15. Buchfink, 2021, Sensitive protein alignments at tree-of-life scale using DIAMOND, Nature Methods, 18, 366, 10.1038/s41592-021-01101-x · DOI · Paper page
  16. Bugg, 1994, From peptidoglycan to glycoproteins: common features of lipid-linked oligosaccharide biosynthesis, FEMS Microbiology Letters, 119, 255, 10.1111/j.1574-6968.1994.tb06898.x · DOI
  17. Burda, 1999, The dolichol pathway of N-linked glycosylation, Biochimica et Biophysica Acta, 1426, 239, 10.1016/s0304-4165(98)00127-5 · DOI
  18. Caramelo, 2007, How sugars convey information on protein conformation in the endoplasmic reticulum, Seminars in Cell & Developmental Biology, 18, 732, 10.1016/j.semcdb.2007.09.006 · DOI
  19. Carugo, 1997, NADP-dependent enzymes. I: Conserved stereochemistry of cofactor binding, Proteins, 28, 10, 10.1002/(sici)1097-0134(199705)28:1<10::aid-prot2>3.0.co;2-n · DOI
  20. Cavalier-Smith, 2020, Multidomain ribosomal protein trees and the planctobacterial origin of neomura (eukaryotes, archaebacteria), Protoplasma, 257, 621, 10.1007/s00709-019-01442-7 · DOI
  21. Chaban, 2006, Identification of genes involved in the biosynthesis and attachment of Methanococcus voltae N-linked glycans: insight into N-linked glycosylation pathways in Archaea, Molecular Microbiology, 61, 259, 10.1111/j.1365-2958.2006.05226.x · DOI
  22. Chaban, 2009, AglC and AglK are involved in biosynthesis and attachment of diacetylated glucuronic acid to the N-glycan in Methanococcus voltae, Journal of Bacteriology, 191, 187, 10.1128/JB.00885-08 · DOI
  23. Chantret, 2005, Two proteins homologous to the N- and C-terminal domains of the bacterial glycosyltransferase MurG are required for the second step of dolichyl-linked oligosaccharide synthesis in Saccharomyces cerevisiae, The Journal of Biological Chemistry, 280, 9236, 10.1074/jbc.M413941200 · DOI
  24. Crouvoisier, 2007, Role of the amino acid invariants in the active site of MurG as evaluated by site-directed mutagenesis, Biochimie, 89, 1498, 10.1016/j.biochi.2007.06.011 · DOI
  25. Da Cunha, 2017, Lokiarchaea are close relatives of Euryarchaeota, not bridging the gap between prokaryotes and eukaryotes, PLOS Genetics, 13, 10.1371/journal.pgen.1006810 · DOI
  26. De Vuyst, 2001, Recent developments in the biosynthesis and applications of heteropolysaccharides from lactic acid bacteria, International Dairy Journal, 11, 687, 10.1016/S0958-6946(01)00114-5 · DOI · Paper page
  27. Drozdetskiy, 2015, JPred4: a protein secondary structure prediction server, Nucleic Acids Research, 43, 10.1093/nar/gkv332 · DOI
  28. Eichler, 2013, A proposal for the naming of N-glycosylation pathway components in Archaea, Glycobiology, 23, 620, 10.1093/glycob/cwt034 · DOI
  29. Eme, 2017, Archaea and the origin of eukaryotes, Nature Reviews. Microbiology, 15, 711, 10.1038/nrmicro.2017.133 · DOI
  30. Fujinami, 2017, Asn-linked oligosaccharide chain of a crenarchaeon, Pyrobaculum calidifontis, is reminiscent of the eukaryotic high-mannose-type glycan, Glycobiology, 27, 701, 10.1093/glycob/cwx044 · DOI
  31. Gandini, 2020, A Transmembrane Crenarchaeal Mannosyltransferase Is Involved in N-Glycan Biosynthesis and Displays an Unexpected Minimal Cellulose-Synthase-like Fold, Journal of Molecular Biology, 432, 4658, 10.1016/j.jmb.2020.06.016 · DOI
  32. Gao, 2005, Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation, The Journal of Biological Chemistry, 280, 36254, 10.1074/jbc.M507569200 · DOI
  33. Gao, 2008, Interaction between the C termini of Alg13 and Alg14 mediates formation of the active UDP-N-acetylglucosamine transferase complex, The Journal of Biological Chemistry, 283, 32534, 10.1074/jbc.M804060200 · DOI
  34. Gloster, 2014, Advances in understanding glycosyltransferases from a structural perspective, Current Opinion in Structural Biology, 28, 131, 10.1016/j.sbi.2014.08.012 · DOI
  35. Grass, 2010, The Haemophilus influenzae HMW1C protein is a glycosyltransferase that transfers hexose residues to asparagine sites in the HMW1 adhesin, PLOS Pathogens, 6, 10.1371/journal.ppat.1000919 · DOI
  36. Guindon, 2010, New algorithms and methods to estimate maximum-likelihood phylogenies: Assessing the performance of PhyML 3.0, Systematic Biology, 59, 307, 10.1093/sysbio/syq010 · DOI · Paper page
  37. Ha, 1999, The kinetic characterization of Escherichia coli MurG using synthetic substrate analogues, Journal of the American Chemical Society, 121, 8415, 10.1021/ja991556t · DOI
  38. Ha, 2000, The 1.9 angstrom crystal structure of Escherichia coli MurG, a membrane-associated glycosyltransferase involved in peptidoglycan biosynthesis, Protein Science, 9, 1045, 10.1110/ps.9.6.1045 · DOI
  39. Helenius, 2004, Roles of N-linked glycans in the endoplasmic reticulum, Annual Review of Biochemistry, 73, 1019, 10.1146/annurev.biochem.73.011303.073752 · DOI · Paper page
  40. Hoang, 2018, UFBoot2: Improving the Ultrafast Bootstrap Approximation, Molecular Biology and Evolution, 35, 518, 10.1093/molbev/msx281 · DOI · Paper page
  41. Hu, 2003, Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases, PNAS, 100, 845, 10.1073/pnas.0235749100 · DOI
  42. Huet, 1983, Archaebacteria and eukaryotes possess DNA-dependent RNA polymerases of a common type, The EMBO Journal, 2, 1291, 10.1002/j.1460-2075.1983.tb01583.x · DOI
  43. Hyatt, 2010, Prodigal: prokaryotic gene recognition and translation initiation site identification, BMC Bioinformatics, 11, 10.1186/1471-2105-11-119 · DOI
  44. Imachi, 2020, Isolation of an archaeon at the prokaryote-eukaryote interface, Nature, 577, 519, 10.1038/s41586-019-1916-6 · DOI · Paper page
  45. Jarrell, 2014, N-linked glycosylation in Archaea: a structural, functional, and genetic analysis, Microbiology and Molecular Biology Reviews, 78, 304, 10.1128/MMBR.00052-13 · DOI
  46. Kalyaanamoorthy, 2017, ModelFinder: fast model selection for accurate phylogenetic estimates, Nature Methods, 14, 587, 10.1038/nmeth.4285 · DOI · Paper page
  47. Kaminski, 2010, AglJ adds the first sugar of the N-linked pentasaccharide decorating the Haloferax volcanii S-layer glycoprotein, Journal of Bacteriology, 192, 5572, 10.1128/JB.00705-10 · DOI
  48. Kaminski, 2013, Phylogenetic- and genome-derived insight into the evolution of N-glycosylation in Archaea, Molecular Phylogenetics and Evolution, 68, 327, 10.1016/j.ympev.2013.03.024 · DOI
  49. Kandler, 1978, Chemical composition of peptidoglycan free cell-walls of methanogenic Bacteria, Archives of Microbiology, 118, 141, 10.1007/BF00415722 · DOI
  50. Katoh, 2013, MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability, Molecular Biology and Evolution, 30, 772, 10.1093/molbev/mst010 · DOI · Paper page
  51. Kelleher, 2006, An evolving view of the eukaryotic oligosaccharyltransferase, Glycobiology, 16, 47R, 10.1093/glycob/cwj066 · DOI
  52. Kleerebezem, 1999, Exopolysaccharides produced by Lactococcus lactis: from genetic engineering to improved rheological properties, Antonie van Leeuwenhoek, 76, 357, 10.1023/A:1002084822851 · DOI
  53. Kolkman, 1997, Functional analysis of glycosyltransferases encoded by the capsular polysaccharide biosynthesis locus of Streptococcus pneumoniae serotype 14, The Journal of Biological Chemistry, 272, 19502, 10.1074/jbc.272.31.19502 · DOI
  54. König, 1982, Structure and modifications of pseudomurein in Methanobacteriales, Zentralblatt Für Bakteriologie Mikrobiologie Und Hygiene, 3, 179, 10.1016/S0721-9571(82)80031-8 · DOI
  55. Kurosawa, 2005, Homologous recombination of exogenous DNA with the Sulfolobus acidocaldarius genome: properties and uses, FEMS Microbiology Letters, 253, 141, 10.1016/j.femsle.2005.09.031 · DOI
  56. Lairson, 2008, Glycosyltransferases: structures, functions, and mechanisms, Annual Review of Biochemistry, 77, 521, 10.1146/annurev.biochem.76.061005.092322 · DOI
  57. Larkin, 2011, The expanding horizons of asparagine-linked glycosylation, Biochemistry, 50, 4411, 10.1021/bi200346n · DOI
  58. Larkin, 2013, Biochemical evidence for an alternate pathway in N-linked glycoprotein biosynthesis, Nature Chemical Biology, 9, 367, 10.1038/nchembio.1249 · DOI
  59. Lehle, 2006, Protein glycosylation, conserved from yeast to man: a model organism helps elucidate congenital human diseases, Angewandte Chemie (International Ed. in English), 45, 6802, 10.1002/anie.200601645 · DOI
  60. Letunic, 2019, Interactive Tree Of Life (iTOL) v4: recent updates and new developments, Nucleic Acids Research, 47, W256, 10.1093/nar/gkz239 · DOI
  61. Liu, 2021, Expanded diversity of Asgard archaea and their relationships with eukaryotes, Nature, 593, 553, 10.1038/s41586-021-03494-3 · DOI
  62. Lombard, 2014, The carbohydrate-active enzymes database (CAZy) in 2013, Nucleic Acids Research, 42, D490, 10.1093/nar/gkt1178 · DOI
  63. Lombard, 2016, The multiple evolutionary origins of the eukaryotic N-glycosylation pathway, Biology Direct, 11, 10.1186/s13062-016-0137-2 · DOI · Paper page
  64. Lu, 2012, Alg14 organizes the formation of a multiglycosyltransferase complex involved in initiation of lipid-linked oligosaccharide biosynthesis, Glycobiology, 22, 504, 10.1093/glycob/cwr162 · DOI
  65. Men, 1998, Substrate synthesis and activity assay for MurG, Journal of the American Chemical Society, 120, 2484, 10.1021/ja974221p · DOI
  66. Mestrom, 2019, Leloir Glycosyltransferases in Applied Biocatalysis: A Multidisciplinary Approach, International Journal of Molecular Sciences, 20, 10.3390/ijms20215263 · DOI
  67. Meyer, 2013, Hot and sweet: protein glycosylation in Crenarchaeota, Biochemical Society Transactions, 41, 384, 10.1042/BST20120296 · DOI
  68. Meyer, 2013, Agl16, a thermophilic glycosyltransferase mediating the last step of N-glycan biosynthesis in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius, Journal of Bacteriology, 195, 2177, 10.1128/JB.00035-13 · DOI
  69. Meyer, 2014, AglB, catalyzing the oligosaccharyl transferase step of the archaeal N-glycosylation process, is essential in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius, MicrobiologyOpen, 3, 531, 10.1002/mbo3.185 · DOI
  70. Meyer, 2017, AglH, a thermophilic UDP-N-acetylglucosamine-1-phosphate:dolichyl phosphate GlcNAc-1-phosphotransferase initiating protein N-glycosylation pathway in Sulfolobus acidocaldarius, is capable of complementing the eukaryal Alg7, Extremophiles, 21, 121, 10.1007/s00792-016-0890-2 · DOI
  71. Minh, 2020, IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era, Molecular Biology and Evolution, 37, 1530, 10.1093/molbev/msaa015 · DOI · Paper page
  72. Nikolayev, 2020, Evolutionary considerations of the oligosaccharyltransferase AglB and other aspects of N-glycosylation across Archaea, Molecular Phylogenetics and Evolution, 153, 10.1016/j.ympev.2020.106951 · DOI
  73. Nothaft, 2010, Protein glycosylation in bacteria: sweeter than ever, Nature Reviews. Microbiology, 8, 765, 10.1038/nrmicro2383 · DOI
  74. Nothaft, 2019, New discoveries in bacterial N-glycosylation to expand the synthetic biology toolbox, Current Opinion in Chemical Biology, 53, 16, 10.1016/j.cbpa.2019.05.032 · DOI
  75. Olm, 2017, dRep: a tool for fast and accurate genomic comparisons that enables improved genome recovery from metagenomes through de-replication, The ISME Journal, 11, 2864, 10.1038/ismej.2017.126 · DOI · Paper page
  76. Palmieri, 2013, Surface-exposed glycoproteins of hyperthermophilic Sulfolobus solfataricus P2 show a common glycosylation profile, Journal of Proteome Research, 12, 2779, 10.1021/pr400123z · DOI
  77. Parks, 2022, GTDB: an ongoing census of bacterial and archaeal diversity through a phylogenetically consistent, rank normalized and complete genome-based taxonomy, Nucleic Acids Research, 50, D785, 10.1093/nar/gkab776 · DOI · Paper page
  78. Petitjean, 2014, Rooting the Domain Archaea by Phylogenomic Analysis Supports the Foundation of the New Kingdom Proteoarchaeota, Genome Biology and Evolution, 7, 191, 10.1093/gbe/evu274 · DOI
  79. Peyfoon, 2010, The S-layer glycoprotein of the crenarchaeote Sulfolobus acidocaldarius is glycosylated at multiple sites with chitobiose-linked N-glycans, Archaea (Vancouver, B.C.), 2010, 10.1155/2010/754101 · DOI
  80. Raman, 2010, NMR structure determination for larger proteins using backbone-only data, Science (New York, N.Y.), 327, 1014, 10.1126/science.1183649 · DOI
  81. Raymann, 2015, The two-domain tree of life is linked to a new root for the Archaea, PNAS, 112, 6670, 10.1073/pnas.1420858112 · DOI
  82. Reily, 2019, Glycosylation in health and disease, Nature Reviews. Nephrology, 15, 346, 10.1038/s41581-019-0129-4 · DOI · Paper page
  83. Samuelson, 2005, The diversity of dolichol-linked precursors to Asn-linked glycans likely results from secondary loss of sets of glycosyltransferases, PNAS, 102, 1548, 10.1073/pnas.0409460102 · DOI
  84. Schwarz, 2011, Mechanisms and principles of N-linked protein glycosylation, Current Opinion in Structural Biology, 21, 576, 10.1016/j.sbi.2011.08.005 · DOI
  85. Seemann, 2014, Prokka: rapid prokaryotic genome annotation, Bioinformatics (Oxford, England), 30, 2068, 10.1093/bioinformatics/btu153 · DOI
  86. Shams-Eldin, 2008, Identification of the archaeal alg7 gene homolog (encoding N-acetylglucosamine-1-phosphate transferase) of the N-linked glycosylation system by cross-domain complementation in Saccharomyces cerevisiae, Journal of Bacteriology, 190, 2217, 10.1128/JB.01778-07 · DOI
  87. Shrimal, 2019, Oligosaccharyltransferase structures provide novel insight into the mechanism of asparagine-linked glycosylation in prokaryotic and eukaryotic cells, Glycobiology, 29, 288, 10.1093/glycob/cwy093 · DOI
  88. Sievers, 2018, Clustal Omega for making accurate alignments of many protein sequences, Protein Science, 27, 135, 10.1002/pro.3290 · DOI · Paper page
  89. Steenwyk, 2020, ClipKIT: A multiple sequence alignment trimming software for accurate phylogenomic inference, PLOS Biology, 18, 10.1371/journal.pbio.3001007 · DOI
  90. Studier, 2014, Stable expression clones and auto-induction for protein production in E. coli, Methods in Molecular Biology (Clifton, N.J.), 1091, 17, 10.1007/978-1-62703-691-7_2 · DOI · Paper page
  91. Taguchi, 2016, Comparative analysis of archaeal lipid-linked oligosaccharides that serve as oligosaccharide donors for Asn glycosylation, The Journal of Biological Chemistry, 291, 11042, 10.1074/jbc.M115.713156 · DOI
  92. Tria, 2017, Phylogenetic rooting using minimal ancestor deviation, Nature Ecology & Evolution, 1, 10.1038/s41559-017-0193 · DOI
  93. van Kranenburg, 1999, Functional analysis of glycosyltransferase genes from Lactococcus lactis and other gram-positive cocci: Complementation, expression, and diversity, Journal of Bacteriology, 181, 6347, 10.1128/JB.181.20.6347-6353.1999 · DOI
  94. van Wolferen, 2020, Species-specific recognition of Sulfolobales mediated by UV-inducible pili and S-layer glycosylation patterns, MBio, 11, 10.1128/mBio.03014-19 · DOI
  95. Varki, 1993, Biological roles of oligosaccharides - all of the theories are correct, Glycobiology, 3, 97, 10.1093/glycob/3.2.97 · DOI
  96. Varki, 1999, Chapter 17, Glycosyltransferases. Essentials of Glycobiolog
  97. Wagner, 2012, Versatile genetic tool Box for the crenarchaeote Sulfolobus acidocaldarius, Frontiers in Microbiology, 3, 10.3389/fmicb.2012.00214 · DOI
  98. Waldo, 1999, Rapid protein-folding assay using green fluorescent protein, Nature Biotechnology, 17, 691, 10.1038/10904 · DOI
  99. Wang, 2008, Solution structure of Alg13: the sugar donor subunit of a yeast N-acetylglucosamine transferase, Structure (London, England, 16, 965, 10.1016/j.str.2008.03.010 · DOI
  100. Waterhouse, 2018, SWISS-MODEL: homology modelling of protein structures and complexes, Nucleic Acids Research, 46, W296, 10.1093/nar/gky427 · DOI
  101. Whitfield, 2017, Essentials of Glycobiology
  102. Wild, 2018, Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation, Science (New York, N.Y.), 359, 545, 10.1126/science.aar5140 · DOI
  103. Wilson, 2007, Ribophorin I acts as a substrate-specific facilitator of N-glycosylation, Journal of Cell Science, 120, 648, 10.1242/jcs.000729 · DOI
  104. Woese, 1977, Phylogenetic structure of the prokaryotic domain: the primary kingdoms, PNAS, 74, 5088, 10.1073/pnas.74.11.5088 · DOI · Paper page
  105. Yurist-Doutsch, 2008, AglF, aglG and aglI, novel members of a gene island involved in the N-glycosylation of the Haloferax volcanii S-layer glycoprotein, Molecular Microbiology, 69, 1234, 10.1111/j.1365-2958.2008.06352.x · DOI
  106. Zähringer, 2000, Cytochrome b##ltsub##gt558/566##lt/sub##gt from the archaeon Sulfolobus acidocaldarius has a unique Asn-linked highly branched hexasaccharide chain containing 6-sulfoquinovose, European Journal of Biochemistry, 267, 4144, 10.1046/j.1432-1327.2000.01446.x · DOI
  107. Zhang, 2018, The essential genome of the crenarchaeal model Sulfolobus islandicus, Nature Communications, 9, 10.1038/s41467-018-07379-4 · DOI
  108. Zielinska, 2010, Precision mapping of an in vivo N-glycoproteome reveals rigid topological and sequence constraints, Cell, 141, 897, 10.1016/j.cell.2010.04.012 · DOI
  109. Zillig, 1989, The phylogenetic relations of DNA-dependent RNA polymerases of archaebacteria, eukaryotes, and eubacteria, Canadian Journal of Microbiology, 35, 73, 10.1139/m89-011 · DOI
  110. Zorzoli, 2019, Streptococcus Lancefield antigen biosynthesis is initiated by a conserved alpha-D-GlcNAc-beta-1,4-L-rhamnosyltransferase, Journal of Biological Chemistry, 294, 15237, 10.1074/jbc.RA119.009894 · DOI

Metadata

Authors
Meyer, B. H., Adam, P. S., Wagstaff, B. A., Kolyfetis, G. E., Probst, A. J., Albers, S. V., & Dorfmueller, H. C.
Affiliations
  • University of Freiburg (DE)
  • University of Duisburg-Essen (DE)
  • University of Dundee (GB)
  • National and Kapodistrian University of Athens (GR)
Corresponding author
  • Meyer, Benjamin H
  • Dorfmueller, Helge C
ORCID
Venue
eLife
Publisher
eLife Sciences Publications, Ltd
Published
2022-04-08
Volume
11
ISSN
2050-084X (ISSN-L)
DOI
10.7554/elife.67448
PMC
PMC8993221
OpenAlex
W4223452448
Cited by
12
References
5
Citations by year
2026: 2 · 2025: 4 · 2024: 4 · 2023: 1 · 2022: 1
FWCI
0.82
Type
journal article
Language
en
Open access
Licence
Locations
  • eLife (publishedVersion, cc-by)
  • bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Discovery Research Portal (University of Dundee) (submittedVersion, cc-by)
  • Universitätsbibliographie, Universität Duisburg-Essen (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • KOPS (University of Konstanz) (submittedVersion, cc-by)
Funders
  • The Wellcome Trust and Royal Society Grant (109357/Z/15/Z)
  • SFG (403222702-SFB 1381)
  • Ministerium für Kultur und Wissenschaft des Landes Nordrhein-Westfalen (Nachwuchsgruppe Dr. Alexander Probst)
  • Alexander von Humboldt Foundation (Postdoctoral fellowship)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Glycosylation and Glycoproteins Research
  • Physical Sciences › Chemistry › Organic Chemistry › Carbohydrate Chemistry and Synthesis
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
Keywords
AGL24, lipid-linked oligosaccharides, crenarchaeon, MurG, eukaryotic origin, horizontal gene transfer, protein evolution, phylogenetic analysis, structural modeling
MeSH terms
Archaea, Disaccharides, Phylogeny, Polysaccharides, Eukaryota

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review