EXPERIMENTAL Brucella suis TYPE 4 INFECTIONS IN DOMESTIC AND WILD ALASKAN CARNIVORES
Abstract
Beagle dogs were readily infected by 1.3 x 10(8) colony forming units (cfu) of Brucella suis type 4 administered either on canned dog food, or intraperitoneally. Such infections were afebrile and otherwise asymptomatic and without any obvious gross lesions. Inoculation of 10(8) cfu B. suis type 4 intraperitoneally into two gravid wolves (Canis lupus) resulted in infections in both animals. About 24 days later they gave birth, apparently at full-term, to two (both alive) and six (two alive and four dead) pups, respectively. Pups born alive died within 24 hours. A black bear (Ursus americanus) infected with between 10(8) and 10(9) cfu yielded serologic and bacteriologic data similar to that derived from the observations on beagles and wolves. Two grizzly bears (Ursus arctos horribilis) were both infected by exposure to 1.3 x 10(9) csf B. suis type 4 placed on canned dog food. Antibody titres reached very high levels within the first two months of infection.
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Transmission of B. suis to humans from dogs via secretions and urine is considered to be possible under favourable circumstances.
“although transmission to humans from dogs via secretions and urine is considered to be possible under favourable circumstances (Neiland & Miller 1981).”
From Raw diets for dogs and cats: a review, with particular reference to microbiological hazards. (2019) · cites this paper as Neiland & Miller 1981
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Raw diets for dogs and cats: a review, with particular reference to microbiological hazards.
Davies, R. H., Lawes, J. R., & Wales, A. D. (2019) · Journal of Small Animal Practice · doi:10.1111/jsap.13000 · Cited by 195 · see citing works
“B. suis has a low infectious dose for humans, and zoonotic disease is often acquired through butchering or consuming wildlife (Woldemeskel 2013), although transmission to humans from dogs via secretions and urine is considered to be possible under favourable circumstances (Neiland & Miller 1981).”
BackgroundClinical Manifestations of Brucellosis in Domestic Animals and Humans
Megid, J., Mathias, L., & Robles, C. (2010) · The Open Veterinary Science Journal · doi:10.2174/1874318801004010119 · Cited by 141 · see citing works
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“Should brucellosis become more prevalent among the different canid species in Yellowstone, impacts on an individual animal could indude reproductive failure as a result of infection (Carmichael and Kennedy, 1970; Neiland and Miller, 1981).”
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Rah, H., Chomel, B., Follmann, E., Kasten, R., Hew, C., Farver, T., Garner, G. W., & Amstrup, S. (2005) · The Veterinary Record · doi:10.1136/vr.156.1.7 · Cited by 89
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Kosoy, M., & Goodrich, I. (2019) · Frontiers in Veterinary Science · doi:10.3389/fvets.2018.00322 · Cited by 51 · see citing works
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Brucellosis – A threat to one health
Tanaya, Batra, M., & Chauhan, R. (2024) · Indian Journal of Comparative Microbiology Immunology and Infectious Diseases · doi:10.5958/0974-0147.2024.00015.9
Rk, N. (n.d.) · doi:10.1097/00000441-194201000-00017
- Authors
- NEILAND, K. A., & MILLER, L. G.
- Affiliations
- Alaska Department of Fish and Game (US)
- United States Department of Health, Education, and Welfare, HCFA-HSQB, Denver, Colorado 80202, USA
- Venue
- Journal of Wildlife Diseases
- Publisher
- Wildlife Disease Association
- Published
- 1981-04
- Volume
- 17
- Issue
- 2
- Pages
- 183-189
- ISSN
- 0090-3558 (ISSN-L)
- OpenAlex
- W2096012707
- Cited by
- 29
- References
- 0
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 2 · 2014: 1 · 2013: 2
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Wildlife Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Veterinary › Small Animals › Brucella: diagnosis, epidemiology, treatment
- Life Sciences › Immunology and Microbiology › Microbiology › Microbial infections and disease research
- Life Sciences › Agricultural and Biological Sciences › Food Science › Salmonella and Campylobacter epidemiology
- Keywords
- brucellosis, carnivores, beagle dogs, wolf, Ursus americanus, grizzly bear, wild carnivores, domestic carnivores, infection route, intraperitoneal inoculation, serological response, antibody titers, fetal death, Alaska
- MeSH terms
- Alaska, Animals, Ursidae, Brucella, Brucellosis, Carnivora, Dog Diseases, Dogs, Female, Male, Pregnancy, Pregnancy Complications, Infectious, Species Specificity
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