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Protective effects from Houttuynia cordata aqueous extract against acetaminophen-induced liver injury
Open accessAbstract
BACKGROUND: aqueous extract (HCAE) against acetaminophen-induced hepatotoxicity in Balb/cA mice were examined. METHODS: HCAE, at 1 or 2 g/L, was added into the drinking water for 4 weeks. Acute liver injury was induced by acetaminophen treatment intraperitoneally (350 mg/kg body weight). RESULTS: <0.05). CONCLUSION: These results support that HCAE could provide hepato-protection.
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“Treatment with paracetamol alone increased the expression of CYP2E1 by 0.6 folds followed with GSH depletion. 39”
From Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1 (2017) · cites this paper as [39]
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Research works printed but not linked: 27
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Cited by
Sorted by citations
Caralluma umbellata Haw. protects liver against paracetamol toxicity and inhibits CYP2E1
Bellamakondi, P. K., Godavarthi, A., & Ibrahim, M. (2017) · BioImpacts · doi:10.15171/bi.2018.04 · Cited by 15
Metadata
- Authors
- Chen, W.-T., Yang, C.-L., & Yin, M.-C.
- Affiliations
- China Medical University (TW)
- Corresponding author
- Yin, Mei-chin
- Venue
- BioMedicine
- Publisher
- China Medical University
- Published
- 2014-03
- Volume
- 4
- Issue
- 1
- Pages
- 5-5
- ISSN
- 2211-8020 (ISSN-L)
- 2211-8039
- PMC
- PMC4264974
- OpenAlex
- W2152594080
- Cited by
- 26
- References
- 0
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 1 · 2022: 4 · 2019: 1 · 2018: 5 · 2017: 6 · 2016: 3 · 2015: 4
- FWCI
- 2.92
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Biomedicine (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- China Medical University
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Drug-Induced Hepatotoxicity and Protection
- Health Sciences › Medicine › Complementary and alternative medicine › Medicinal plant effects and applications
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Plant Toxicity and Pharmacological Properties
- Keywords
- Houttuynia cordata, aqueous extract, paracetamol, hepatotoxicity, liver injury, hepatoprotection, acute liver injury, herbal medicine
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