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Anvi’o: an advanced analysis and visualization platform for ‘omics data

Open access
Eren, A. Murat, Esen, Özcan C., Quince, Christopher, Vineis, Joseph H., Morrison, Hilary G., Sogin, Mitchell L., Delmont, Tom O.·2015·PeerJ

Abstract

Advances in high-throughput sequencing and ‘omics technologies are revolutionizing studies of naturally occurring microbial communities. Comprehensive investigations of microbial lifestyles require the ability to interactively organize and visualize genetic information and to incorporate subtle differences that enable greater resolution of complex data. Here we introduce anvi’o, an advanced analysis and visualization platform that offers automated and human-guided characterization of microbial genomes in metagenomic assemblies, with interactive interfaces that can link ‘omics data from multiple sources into a single, intuitive display. Its extensible visualization approach distills multiple dimensions of information about each contig, offering a dynamic and unified work environment for data exploration, manipulation, and reporting. Using anvi’o, we re-analyzed publicly available datasets and explored temporal genomic changes within naturally occurring microbial populations through de novo characterization of single nucleotide variations, and linked cultivar and single-cell genomes with metagenomic and metatranscriptomic data. Anvi’o is an open-source platform that empowers researchers without extensive bioinformatics skills to perform and communicate in-depth analyses on large ‘omics datasets.

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Metadata

Authors
Eren, A. M., Esen, Ö. C., Quince, C., Vineis, J. H., Morrison, H. G., Sogin, M. L., & Delmont, T. O.
Venue
PeerJ
Publisher
PeerJ
Published
2015-10-08
Volume
3
Pages
e1319
ISSN
2167-8359 (ISSN-L)
OpenAlex
W1958058086
Cited by
1,887
References
9
FWCI
23.67
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Anvi’o: an advanced analysis and visualization platform for ‘omics data. https://app.cochat.ai/papers/10.7717/peerj.1319
The paper
Eren, A. M., Esen, Ö. C., Quince, C., Vineis, J. H., Morrison, H. G., Sogin, M. L., & Delmont, T. O. (2015). Anvi’o: an advanced analysis and visualization platform for ‘omics data. PeerJ. https://doi.org/10.7717/peerj.1319

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.