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Dysphagia as the Presenting Symptom of Laryngeal Tuberculosis
Open accessAbstract
Laryngeal tuberculosis (TB) is a rare form of tuberculosis that most commonly presents with dysphagia and weight loss. We report a case of a 75-year-old Vietnamese male who presented with dysphagia, odynophagia, and a 30-pound weight loss over the two months prior to presentation. Nasopharyngeal evaluation with microdirect laryngoscopy was performed as part of the workup and revealed lesions of the epiglottis and left vocal cord. A tissue biopsy and quantiferon testing confirmed the diagnosis of tuberculosis. The patient was started on quadruple therapy and is currently receiving treatment. This case highlights the need for consideration of the rare, yet important, differential of laryngeal TB in patients presenting with non-specific complaints such as dysphagia and weight loss.
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“Laryngeal TB is another notable manifestation, though less common than enlarged cervical lymph nodes. It can present with symptoms such as dysphonia and dysphagia [22,36].”
From Head and Neck Tuberculosis: A Rare Diagnosis and the Role of Surgical Biopsy and Histopathological Evaluation in Extrapulmonary Disease (2025) · cites this paper as [36]
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Research works printed but not linked: 8
- Dheda K, Barry CE 3rd, Maartens G. Tuberculosis. Lancet. 2016, 19:1211-26. 10.1016/S0140-6736(15)00151-8 · DOI
- Furin J, Cox H, Pai M. Tuberculosis. Lancet. 2019, 20:1642-1656. 10.1016/S0140-6736(19)30308-3 · DOI
- Wang CC, Lin CC, Wang CP, Liu SA, Jiang RS. Laryngeal tuberculosis: a review of 26 cases. Otolaryngol Head Neck Surg. 2007, 137:582-8. 10.1016/j.otohns.2007.04.002 · DOI
- Benwill JL, Sarria JC. Laryngeal tuberculosis in the United States of America: a forgotten disease. Scand J Infect Dis. 2014, 46:241-9. 10.3109/00365548.2013.877157 · DOI
- Kiakojuri K, Hasanjani Roushan MR. Laryngeal tuberculosis without pulmonary involvement. Caspian J Intern Med. 2012, 3:397-9.
- Sakthivel P, Singh CA, Sharma SC, Kanodia A, Jat B, Rajeshwari M. Primary laryngeal tuberculosis-“the great masquerader”. Clin Case Rep Rev. 2017, 3:1-3. 10.15761/CCRR.1000335 · DOI
- Kurokawa M, Nibu K, Ichimura K, Nishino H. Laryngeal tuberculosis: a report of 17 cases. Auris Nasus Larynx. 2015, 42:305-10. 10.1016/j.anl.2015.02.012 · DOI
- El Kettani NE, El Hassani M, Chakir N, Jiddane M. Primary laryngeal tuberculosis mimicking laryngeal carcinoma: CT scan features. Indian J Radiol Imaging. 2010, 20:11-2. · DOI
Cited by
Sorted by citations
Mogoantă, C. A., Osman, A., Georgescu, A.-M., Mitroi, A. M., Busuioc, C. I., Tănase, I., Cioboată, R., Liliac, I. M., Cimpeanu, O. L., & Ciolofan, M. S. (2025) · Pathogens · doi:10.3390/pathogens14050479 · Cited by 2
“It can present with symptoms such as dysphonia and dysphagia [22,36].”
Metadata
- Authors
- Kandah, E., Konda, R., Malik, B., Madadha, A., & Kunadi, A.
- Affiliations
- University of Jordan (JO)
- Corresponding author
- Kandah, Emad
- Venue
- Cureus
- Published
- 2021-04-15
- Volume
- 13
- Issue
- 4
- Pages
- e14495-e14495
- ISSN
- 2168-8184 (ISSN-L)
- PMC
- PMC8122223
- OpenAlex
- W3156873650
- Cited by
- 4
- References
- 0
- Citations by year
- 2025: 2 · 2023: 1 · 2021: 1
- FWCI
- 0.47
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Cureus (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Diagnosis and treatment of tuberculosis
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Health Sciences › Medicine › Infectious Diseases › Infectious Diseases and Tuberculosis
- Keywords
- laryngeal tuberculosis, dysphagia, odynophagia, weight loss, vocal cord lesions, Quantiferon test, quadruple therapy, differential diagnosis
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