Plasmodium vivax Induced Acute Respiratory Distress Syndrome – A Diagnostic and Therapeutic Dilemma in Preeclampsia
Open accessAbstract
A 27-year-old woman, G2P1L1 at 36 weeks gestation presented to our hospital with complaints of fever with chills and rigor since five days.There was no prior history of any obstetric or medical problems.She underwent lower segment caesarean section four years back for breech presentation.On examination, she was conscious and oriented, having mild pallor and icterus.Her temperature was 102.6°F,PR 128 bpm, RR 18/ min, BP 146/94 mmHg, O 2 saturation 100% at room air.Chest was clear with normal vesicular breathing and cardiovascular system.There was no hepatosplenomegaly and fundal height was 36 weeks, cephalic relaxed and fetal heart rate was 140 bpm regular.Laboratory investigation were -Hb 10.2 g%, TLC 8400, platelet count 1.2 L, random blood sugar was 84 mg/dl, serum electrolytes Na + 136 and K + 3.8 mg, total serum bilirubin was 2.82, indirect 2.14 and direct 0.68, SGOT/PT 69/60, blood urea 18 mg/dl and serum creatinine 0.7 mg/dl.Dipstick showed 1+ albuminuria.Viral markers, peripheral smear for malarial parasite and dengue serology were negative.Although widal was positive in titres of 1:160, urine and blood culture reported no growth.Ultrasound whole abdomen revealed mild splenomegaly.Provisional diagnosis of non severe preeclampsia with typhoid fever was made.
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Maternal anemia and infections can impair the supply of oxygen and nutrients to the fetus, contributing to outcomes like intrauterine growth restriction and preterm delivery.
“Maternal anemia and infections can impair the supply of oxygen and nutrients to the fetus [89], contributing to outcomes like intrauterine growth restriction and preterm delivery [90, 91].”
From Current update on malaria in pregnancy: a systematic review (2025) · cites this paper as [90]
The Discussion (page not specified) says malaria during pregnancy can cause maternal anaemia and that maternal complications can adversely affect the fetus. It does not say that anaemia or infection impairs the fetus’s oxygen and nutrient supply—the mechanism attributed to this source by citation [89]. The growth-restriction and preterm-delivery outcomes are cited separately to [90, 91]. (LLM, conf=0.83)
Experimental — accuracy not yet measuredP.vivax infection during pregnancy can also cause severe pre-eclampsia and trigger acute respiratory distress syndrome (ARDS).
“Additionally, studies have shown that P.vivax infection during pregnancy can also cause severe pre-eclampsia and trigger acute respiratory distress syndrome (ARDS) [90, 91].”
From Current update on malaria in pregnancy: a systematic review (2025) · cites this paper as [90]
The Discussion (pp. QD03–QD04) reports acute respiratory distress caused by P. vivax in a pregnant woman with preeclampsia. It does not say the infection caused her preeclampsia; the Conclusion instead says malaria-related respiratory distress was initially confused with pulmonary symptoms of severe preeclampsia. (LLM, conf=0.90)
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Cites
McGready, R., Wongsaen, K., Chu, C. S., Tun, N. W., Chotivanich, K., White, N. J., & Nosten, F. (2014) · Malaria Journal · doi:10.1186/1475-2875-13-191 · Cited by 27 · see citing works
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Research works printed but not linked: 10
- Plasmodium vivax: clinical spectrum, risk factors and pathogenesis. Adv Parasitol. 2012;80:151-201.
- Greenwood B, Mutabingwa T. Malaria in 2002. Nature. 2002;415:670-72.
- Valecha N, Bhatia S, Mehta S, Biswas S, Dash AP. Congenital malaria with [5] atypical presentation: a case report from low transmission area in India. Malar J. 2007;6:43.
- Munteis E, Mellibovsky L, Márquez MA, Mínguez S, Vázquez E, Díez A. Pulmonary [7] involvement in a case of Plasmodium vivax malaria. Chest. 1997;111(3):834-35.
- Tan LK, Yacoub S, Scott S, Bhagani S, Jacobs M. Acute lung injury and [8] other serious complications of Plasmodium vivax malaria. Lancet Infect Dis. 2008;8:449-54.
- Anstey NM, Jacups SP, Cain T, Pearson T, Ziesing PJ, Fisher DA, et al. Pulmonary [9] manifestations of uncomplicated falciparum and vivax malaria: cough, small airways obstruction, impaired gas transfer, and increased pulmonary phagocytic activity. J Infect Dis. 2002;185:1326-34.
- Mukherjee T, Lavania AK. Acute respiratory distress syndrome due to Vivax [10] malaria. MJAFI. 2008;64:365-66.
- Ades V. Safety, pharmacokinetics and efficacy of artemisinins in pregnancy. Infect [11] Dis Rep. 2011;83(1):e8.
- of the combination artesunate and pyrimethamine-sulfadoxine given during pregnancy. Trans R Soc Trop Med Hyg. 2001;95:424-28.
- E-mail: gautamdrricha1@gmail.com Financial OR OtheR cOmPetinG inteReStS: None. Date of Submission: nov 19, 2016 Date of Peer Review: jan 10, 2017 Date of Acceptance: jan 18, 2017 Date of Publishing: apr 01, 2017
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Current update on malaria in pregnancy: a systematic review
Minwuyelet, A., Yewhalaw, D., Siferih, M., & Atenafu, G. (2025) · Tropical Diseases, Travel Medicine and Vaccines · doi:10.1186/s40794-025-00248-1 · Cited by 49 · see citing works
- Authors
- Sharma, R.
- Affiliations
- University College of Medical Sciences (IN)
- Corresponding author
- Sharma, Richa
- Venue
- JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
- Publisher
- JCDR Research and Publications
- Published
- 2017
- Volume
- 11
- Issue
- 4
- Pages
- QD03-QD04
- ISSN
- 0973-709X (ISSN-L)
- 2249-782X
- PMC
- PMC5449862
- OpenAlex
- W2617088397
- Cited by
- 4
- References
- 1
- Citations by year
- 2023: 3 · 2021: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
- Keywords
- Plasmodium vivax, acute respiratory distress syndrome, preeclampsia, malaria in pregnancy, fever of unknown origin, hypokalemia, jaundice, splenomegaly, Widal test, differential diagnosis
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