Management of acute meningitis
Open accessAbstract
Acute meningitis remains a devastating disease. Clinicians need a low threshold for suspecting meningitis, to undertake appropriate investigations and provide treatment in a timely manner, to minimise the risk of poor outcome in bacterial disease, while limiting unnecessary treatment in viral meningitis.
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Viral infections can lead to a modest change in cerebrospinal fluid parameters.
“These results are consistent with the assumption, that viral infections can lead to a modest change in cerebrospinal fluid parameters (18, 27)”
From Utilization of a Meningitis/Encephalitis PCR panel at the University Hospital Basel – a retrospective study to develop a diagnostic decision rule (2024) · cites this paper as [18]
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References 28 · Cited by 87
Research works printed but not linked: 1
- Floren-Zabala L , Chamizo-Lopez FJ , Eisman-Maraver A et al. [Aseptic meningitis in an adult population. Etiology and utility of molecular techniques in the clinical management of patients] . Enferm Infecc Microbiol Clin 2012 ; 30 : 361 -6 .
- Authors
- Griffiths, M. J., McGill, F., & Solomon, T.
- Affiliations
- University of Liverpool (GB)
- Corresponding author
- Griffiths, Michael J
- Venue
- Clinical Medicine
- Publisher
- Elsevier BV
- Published
- 2018-04
- Volume
- 18
- Issue
- 2
- Pages
- 164-169
- ISSN
- 1470-2118 (ISSN-L)
- PMC
- PMC6303447
- OpenAlex
- W2795757548
- Cited by
- 87
- References
- 28
- Citations by year
- 2026: 3 · 2025: 12 · 2024: 12 · 2023: 16 · 2022: 13 · 2021: 16 · 2020: 7 · 2019: 5 · 2018: 3
- FWCI
- 6.24
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Clinical Medicine (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute for Health and Care Research (IS-HPU-1112−10117, 12/205/28, RP-PG-0108-10048, NF-SI-0514-10177, EME/12/205/28)
- Medical Research Council (MC_PC_15096)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Health Sciences › Medicine › Infectious Diseases › Infectious Encephalopathies and Encephalitis
- Health Sciences › Medicine › Surgery › Infectious Diseases and Tuberculosis
- Keywords
- acute meningitis, bacterial meningitis, viral meningitis, clinical suspicion, diagnostic workup, treatment, clinical outcomes, unnecessary treatment
- MeSH terms
- Acute Disease, Anti-Bacterial Agents, Antiviral Agents, Bacterial Infections, Diagnosis, Differential, Humans, Meningitis, Viral
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