Yusa, Kosuke

Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens

Behan, F. M., Iorio, F., Picco, G., Gonçalves, E., Beaver, C. M., Migliardi, G., Santos, R., Rao, Y., Sassi, F., Pinnelli, M., et al. (2019) · Nature

CRISPR and Genetic EngineeringChromatin Remodeling and Cancer

Cited by 1,338

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

Koike-Yusa, H., Li, Y., Tan, E.-P., Velasco-Herrera, M. D. C., & Yusa, K. (2014) · Nature Biotechnology

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 1,064

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

Tzelepis, K., Koike-Yusa, H., De Braekeleer, E., Li, Y., Metzakopian, E., Dovey, O. M., Mupo, A., Grinkevich, V., Li, M., Mazan, M., et al. (2016) · Cell Reports

Acute Myeloid Leukemia ResearchChromatin Remodeling and Cancer

Cited by 761

Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes.

Mali, P., Chou, B.-K., Yen, J., Ye, Z., Zou, J., Dowey, S., Brodsky, R. A., Ohm, J. E., Yu, W., Baylin, S. B., et al. (2010) · Stem Cells

Pluripotent Stem Cells ResearchEpigenetics and DNA Methylation

Cited by 417

Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal Development

Miyamoto, K., Teperek, M., Yusa, K., Allen, G. E., Bradshaw, C. R., & Gurdon, J. B. (2013) · Science

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 91

RENGE infers gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations

Ishikawa, M., Sugino, S., Masuda, Y., Tarumoto, Y., Seto, Y., Taniyama, N., Wagai, F., Yamauchi, Y., Kojima, Y., Kiryu, H., et al. (2023) · Communications Biology

Gene Regulatory Network AnalysisSingle-cell and spatial transcriptomics

Cited by 22