Siu, Lillian L.
University Health Network · Princess Margaret Cancer Centre
17 papers on CoChatORCID 0000-0002-3500-0540
Most cited papers
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AACR Project GENIE: Powering Precision Medicine through an International Consortium
The AACR Project GENIE Consortium, The AACR Project GENIE Consortium, André, F., Arnedos, M., Baras, A. S., Baselga, J., Bedard, P. L., Berger, M. F., Bierkens, M., Calvo, F., et al. (2017) · Cancer Discovery
Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations
Cited by 1,964
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Phase I and Pharmacologic Study of OSI-774, an Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Advanced Solid Malignancies
Hidalgo, M., Siu, L. L., Nemunaitis, J., Rizzo, J., Hammond, L. A., Takimoto, C., Eckhardt, S. G., Tolcher, A., Britten, C. D., Denis, L., et al. (2001) · Journal of Clinical Oncology
HER2/EGFR in Cancer ResearchLung Cancer Treatments and Mutations
Cited by 1,001
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Dose Escalation Methods in Phase I Cancer Clinical Trials
Le Tourneau, C., Lee, J. J., & Siu, L. L. (2009) · JNCI: Journal of the National Cancer Institute
Statistical Methods in Clinical TrialsPharmaceutical studies and practices
Cited by 867
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Multicenter Phase II Study of Erlotinib, an Oral Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck
Soulieres, D., Senzer, N. N., Vokes, E. E., Hidalgo, M., Agarwala, S. S., & Siu, L. L. (2004) · Journal of Clinical Oncology
Head and Neck Cancer StudiesHER2/EGFR in Cancer Research
Cited by 807
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Circulating tumor DNA and liquid biopsy in oncology
Cescon, D. W., Bratman, S. V., Chan, S. M., & Siu, L. L. (2020) · Nature Cancer
Cancer Genomics and DiagnosticsPrenatal Screening and Diagnostics
Cited by 600
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Personalized circulating tumor DNA analysis as a predictive biomarker in solid tumor patients treated with pembrolizumab
Bratman, S. V., Yang, S. Y. C., Iafolla, M. A. J., Liu, Z., Hansen, A. R., Bedard, P. L., Lheureux, S., Spreafico, A., Razak, A. A., Shchegrova, S., et al. (2020) · Nature Cancer
Cancer Immunotherapy and BiomarkersCancer Genomics and Diagnostics
Cited by 487
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Phase Ib study of atezolizumab combined with cobimetinib in patients with solid tumors.
Hellmann, M. D., Kim, T.-W., Lee, C. B., Goh, B.-C., Miller, W. H., Oh, D.-Y., Jamal, R., Chee, C.-E., Chow, L. Q. M., Gainor, J. F., et al. (2019) · Annals of Oncology
Cancer Immunotherapy and BiomarkersMelanoma and MAPK Pathways
Cited by 174
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A six-weekly dosing schedule for pembrolizumab in patients with cancer based on evaluation using modelling and simulation
Lala, M., Li, T. R., de Alwis, D. P., Sinha, V., Mayawala, K., Yamamoto, N., Siu, L. L., Chartash, E., Aboshady, H., & Jain, L. (2020) · European Journal of Cancer
Cancer Immunotherapy and BiomarkersPharmaceutical studies and practices
Cited by 165
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Ocular Toxicity of Targeted Therapies
Renouf, D. J., Velazquez-Martin, J. P., Simpson, R., Siu, L. L., & Bedard, P. L. (2012) · Journal of Clinical Oncology
Drug-Induced Ocular ToxicityChemotherapy-related skin toxicity
Cited by 139
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Testing personalized medicine: patient and physician expectations of next-generation genomic sequencing in late-stage cancer care
Miller, F. A., Hayeems, R. Z., Bytautas, J. P., Bedard, P. L., Ernst, S., Hirte, H., Hotte, S., Oza, A., Razak, A., Welch, S., et al. (2014) · European Journal of Human Genetics
BRCA gene mutations in cancerCancer Genomics and Diagnostics
Cited by 116
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Phase I Dose Finding Studies of Obatoclax (GX15-070), a Small Molecule Pan-BCL-2 Family Antagonist, in Patients with Advanced Solid Tumors or Lymphoma
Hwang, J. J., Kuruvilla, J., Mendelson, D., Pishvaian, M. J., Deeken, J. F., Siu, L. L., Berger, M. S., Viallet, J., & Marshall, J. L. (2010) · Clinical Cancer Research
Cell death mechanisms and regulationCancer-related Molecular Pathways
Cited by 109
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A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer
Wainberg, Z. A., Alsina, M., Soares, H. P., Braña, I., Britten, C. D., Del Conte, G., Ezeh, P., Houk, B., Kern, K. A., Leong, S., et al. (2017) · Targeted Oncology
PI3K/AKT/mTOR signaling in cancerColorectal Cancer Treatments and Studies
Cited by 98
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Initial results from a dose finding study of TNO155, a SHP2 inhibitor, in adults with advanced solid tumors
Brana, I., Shapiro, G., Johnson, M. L., Yu, H. A., Robbrecht, D., Tan, D. S.-W., Siu, L. L., Minami, H., Steeghs, N., Hengelage, T., et al. (2021) · Journal of Clinical Oncology
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 79
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Delayed immune-related adverse events in assessment for dose-limiting toxicity in early phase immunotherapy trials
Kanjanapan, Y., Day, D., Butler, M. O., Wang, L., Joshua, A. M., Hogg, D., Leighl, N. B., Razak, A. R. A., Hansen, A. R., Boujos, S., et al. (2019) · European Journal of Cancer
Cancer Immunotherapy and BiomarkersPharmacovigilance and Adverse Drug Reactions
Cited by 72
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Bugs as drugs: The role of microbiome in cancer focusing on immunotherapeutics
Araujo, D. V., Watson, G. A., Oliva, M., Heirali, A., Coburn, B., Spreafico, A., & Siu, L. L. (2021) · Cancer Treatment Reviews
Gut microbiota and healthCancer Immunotherapy and Biomarkers
Cited by 29
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AVID200, first‐in‐class TGF‐beta 1 and 3 selective and potent inhibitor: Safety and biomarker results of a phase I monotherapy dose‐escalation study in patients with advanced solid tumors
Yap, T. A., Lakhani, N. J., Araujo, D. V., Rodon Ahnert, J., Chandana, S. R., Sharma, M., Denis, J.-F., Gruosso, T., Tremblay, G., O'Connor, M., et al. (2020) · Journal of Clinical Oncology
TGF-β signaling in diseasesCancer Immunotherapy and Biomarkers
Cited by 26
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Phase Ib/II Study of the Efficacy and Safety of Binimetinib (MEK162) Plus Panitumumab for Mutant or Wild-Type RAS Metastatic Colorectal Cancer
Van Cutsem, E., Yaeger, R., Delord, J.-P., Tabernero, J., Siu, L. L., Ducreux, M., Siena, S., Elez, E., Kasper, S., Zander, T., et al. (2023) · The Oncologist
Colorectal Cancer Treatments and StudiesColorectal Cancer Surgical Treatments
Cited by 3
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