Eelen, Guy

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

Cantelmo, A. R., Conradi, L.-C., Brajic, A., Goveia, J., Kalucka, J., Pircher, A., Chaturvedi, P., Hol, J., Thienpont, B., Teuwen, L.-A., et al. (2016) · Cancer Cell

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

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Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Schoors, S., Bruning, U., Missiaen, R., Queiroz, K. C. S., Borgers, G., Elia, I., Zecchin, A., Cantelmo, A. R., Christen, S., Goveia, J., et al. (2015) · Nature

Cancer, Lipids, and MetabolismAngiogenesis and VEGF in Cancer

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FOXO1 couples metabolic activity and growth state in the vascular endothelium

Wilhelm, K., Happel, K., Eelen, G., Schoors, S., Oellerich, M. F., Lim, R., Zimmermann, B., Aspalter, I. M., Franco, C. A., Boettger, T., et al. (2016) · Nature

FOXO transcription factor regulationAngiogenesis and VEGF in Cancer

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Role of glutamine and interlinked asparagine metabolism in vessel formation

Huang, H., Vandekeere, S., Kalucka, J., Bierhansl, L., Zecchin, A., Brüning, U., Visnagri, A., Yuldasheva, N., Goveia, J., Cruys, B., et al. (2017) · The EMBO Journal

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

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Role of glutamine synthetase in angiogenesis beyond glutamine synthesis

Eelen, G., Dubois, C., Cantelmo, A. R., Goveia, J., Brüning, U., DeRan, M., Jarugumilli, G., van Rijssel, J., Saladino, G., Comitani, F., et al. (2018) · Nature

Angiogenesis and VEGF in CancerProtein Kinase Regulation and GTPase Signaling

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An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

Goveia, J., Rohlenova, K., Taverna, F., Treps, L., Conradi, L.-C., Pircher, A., Geldhof, V., de Rooij, L. P. M. H., Kalucka, J., Sokol, L., et al. (2020) · Cancer Cell

Angiogenesis and VEGF in CancerSingle-cell and spatial transcriptomics

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VEGF-B prevents excessive angiogenesis by inhibiting FGF2/FGFR1 pathway

Lee, C., Chen, R., Sun, G., Liu, X., Lin, X., He, C., Xing, L., Liu, L., Jensen, L. D., Kumar, A., et al. (2023) · Signal Transduction and Targeted Therapy

Angiogenesis and VEGF in CancerFibroblast Growth Factor Research

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Targeting endothelial metabolism for anti-angiogenesis therapy: A pharmacological perspective

Missiaen, R., Morales-Rodriguez, F., Eelen, G., & Carmeliet, P. (2017) · Vascular Pharmacology

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

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Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy

Eelen, G., Vanden Bempt, I., Verlinden, L., Drijkoningen, M., Smeets, A., Neven, P., Christiaens, M. R., Marchal, K., Bouillon, R., & Verstuyf, A. (2008) · Oncogene

Cancer-related Molecular PathwaysBRCA gene mutations in cancer

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