Loeffler, Johannes R.

De novo-designed pMHC binders facilitate T cell–mediated cytotoxicity toward cancer cells

Johansen, K. H., Wolff, D. S., Scapolo, B., Fernández-Quintero, M. L., Risager Christensen, C., Loeffler, J. R., Rivera-de-Torre, E., Overath, M. D., Kjærgaard Munk, K., Morell, O., et al. (2025) · Science

vaccines and immunoinformatics approachesCAR-T cell therapy research

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Broadly inhibitory antibodies against severe malaria virulence proteins

Reyes, R. A., Raghavan, S. S. R., Hurlburt, N. K., Introini, V., Kana, I. H., Jensen, R. W., Martinez-Scholze, E., Gestal-Mato, M., Bau, C. B., Fernández-Quintero, M. L., et al. (2024) · Nature

Malaria Research and ControlMonoclonal and Polyclonal Antibodies Research

Cited by 35

Broadly inhibitory antibodies to severe malaria virulence proteins

Reyes, R. A., Raghavan, S. S. R., Hurlburt, N. K., Introini, V., Bol, S., Kana, I. H., Jensen, R. W., Martinez-Scholze, E., Gestal-Mato, M., López-Gutiérrez, B., et al. (2024) · Nature

Malaria Research and ControlMonoclonal and Polyclonal Antibodies Research

Cited by 35

Predicting the conformational flexibility of antibody and T cell receptor complementarity-determining regions

Spoendlin, F. C., Fernández-Quintero, M. L., Raghavan, S. S. R., Turner, H. L., Gharpure, A., Loeffler, J. R., Wong, W. K., Bujotzek, A., Georges, G., Ward, A. B., et al. (2025) · Nature Machine Intelligence

Protein Structure and Dynamicsvaccines and immunoinformatics approaches

Cited by 20

Predicting the conformational flexibility of antibody and T-cell receptor CDRs

Spoendlin, F. C., Fernández-Quintero, M. L., Raghavan, S. S. R., Turner, H. L., Gharpure, A., Loeffler, J. R., Wong, W. K., Bujotzek, A., Georges, G., Ward, A. B., et al. (2025) · Nature Machine Intelligence

Protein Structure and Dynamicsvaccines and immunoinformatics approaches

Cited by 20

Assessing AF2’s ability to predict structural ensembles of proteins

Riccabona, J. R., Spoendlin, F. C., Fischer, A.-L. M., Loeffler, J. R., Quoika, P. K., Jenkins, T. P., Ferguson, J. A., Smorodina, E., Laustsen, A. H., Greiff, V., et al. (2024) · Structure

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 17

Phage display assisted discovery of a pH ‐dependent anti‐α‐cobratoxin antibody from a natural variable domain library

Tulika, T., Pedersen, R. W., Rimbault, C., Ahmadi, S., Rivera‐de‐Torre, E., Fernández‐Quintero, M. L., Loeffler, J. R., Bohn, M., Ljungars, A., Ledsgaard, L., et al. (2023) · Protein Science

Monoclonal and Polyclonal Antibodies ResearchVenomous Animal Envenomation and Studies

Cited by 11

Assessing AF2’s ability to predict structural ensembles of proteins

Riccabona, J. R., Spoendlin, F. C., Fischer, A.-L. M., Loeffler, J. R., Quoika, P. K., Jenkins, T. P., Ferguson, J. A., Smorodina, E., Laustsen, A. H., Greiff, V., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory)

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 2