Gross, Steven S.

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

Yun, J., Mullarky, E., Lu, C., Bosch, K. N., Kavalier, A., Rivera, K., Roper, J., Chio, I. I. C., Giannopoulou, E. G., Rago, C., et al. (2015) · Science

Vitamin C and Antioxidants ResearchCancer, Hypoxia, and Metabolism

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Metabolomics enables precision medicine: “A White Paper, Community Perspective”

for “Precision Medicine and Pharmacometabolomics Task Group”-Metabolomics Society Initiative, Beger, R. D., Dunn, W., Schmidt, M. A., Gross, S. S., Kirwan, J. A., Cascante, M., Brennan, L., Wishart, D. S., Oresic, M., et al. (2016) · Metabolomics

Metabolomics and Mass Spectrometry StudiesHealth, Environment, Cognitive Aging

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Activated murine macrophages secrete a metabolite of arginine with the bioactivity of endothelium-derived relaxing factor and the chemical reactivity of nitric oxide

Stuehr, D. J., Gross, S. S., Sakuma, I., Levi, R., & Nathan, C. F. (1989) · The Journal of experimental medicine

Nitric Oxide and Endothelin EffectsImmune cells in cancer

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NG-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo: a role for nitric oxide in the central regulation of sympathetic tone?

Sakuma, I., Togashi, H., Yoshioka, M., Saito, H., Yanagida, M., Tamura, M., Kobayashi, T., Yasuda, H., Gross, S. S., & Levi, R. (1992) · Circulation Research

Nitric Oxide and Endothelin EffectsHeart Rate Variability and Autonomic Control

Cited by 384

High-fructose corn syrup enhances intestinal tumor growth in mice

Goncalves, M. D., Lu, C., Tutnauer, J., Hartman, T. E., Hwang, S.-K., Murphy, C. J., Pauli, C., Morris, R., Taylor, S., Bosch, K., et al. (2019) · Science

Diet, Metabolism, and DiseaseMetabolism, Diabetes, and Cancer

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Ratio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs. superoxide production by eNOS

Crabtree, M. J., Smith, C. L., Lam, G., Goligorsky, M. S., & Gross, S. S. (2008) · American Journal of Physiology-Heart and Circulatory Physiology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

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Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology

Nuriel, T., Angulo, S. L., Khan, U., Ashok, A., Chen, Q., Figueroa, H. Y., Emrani, S., Liu, L., Herman, M., Barrett, G., et al. (2017) · Nature Communications

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

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L-arginine availability determines the duration of acetylcholine-induced systemic vasodilatation in vivo

Aisaka, K., Gross, S. S., Griffith, O. W., & Levi, R. (1989) · Biochemical and Biophysical Research Communications

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 123

APOE4 is Associated with Differential Regional Vulnerability to Bioenergetic Deficits in Aged APOE Mice

Area-Gomez, E., Larrea, D., Pera, M., Agrawal, R. R., Guilfoyle, D. N., Pirhaji, L., Shannon, K., Arain, H. A., Ashok, A., Chen, Q., et al. (2020) · Scientific Reports

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

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