Mulloy, James C.

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Zuber, J., Shi, J., Wang, E., Rappaport, A. R., Herrmann, H., Sison, E. A., Magoon, D., Qi, J., Blatt, K., Wunderlich, M., et al. (2011) · Nature

Protein Degradation and InhibitorsAcute Myeloid Leukemia Research

Cited by 1,870

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

Su, R., Dong, L., Li, C., Nachtergaele, S., Wunderlich, M., Qing, Y., Deng, X., Wang, Y., Weng, X., Hu, C., et al. (2018) · Cell

RNA modifications and cancerAcute Myeloid Leukemia Research

Cited by 1,137

Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I

Migone, T.-S., Lin, J.-X., Cereseto, A., Mulloy, J. C., O'Shea, J. J., Franchini, G., & Leonard, W. J. (1995) · Science

T-cell and Retrovirus StudiesCytokine Signaling Pathways and Interactions

Cited by 557

AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3

Wunderlich, M., Chou, F.-S., Link, K. A., Mizukawa, B., Perry, R. L., Carroll, M., & Mulloy, J. C. (2010) · Leukemia

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 415

Rac1 GTPase: A “Rac” of All Trades

Bosco, E. E., Mulloy, J. C., & Zheng, Y. (2009) · Cellular and Molecular Life Sciences

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 350

The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia

Weng, H., Huang, F., Yu, Z., Chen, Z., Prince, E., Kang, Y., Zhou, K., Li, W., Hu, J., Fu, C., et al. (2022) · Cancer Cell

RNA modifications and cancerAcute Myeloid Leukemia Research

Cited by 336

The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

Mulloy, J. C., Cammenga, J., MacKenzie, K. L., Berguido, F. J., Moore, M. A. S., & Nimer, S. D. (2002) · Blood

Acute Myeloid Leukemia ResearchHematopoietic Stem Cell Transplantation

Cited by 208

Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome

Rhyasen, G. W., Bolanos, L., Fang, J., Jerez, A., Wunderlich, M., Rigolino, C., Mathews, L., Ferrer, M., Southall, N., Guha, R., et al. (2013) · Cancer Cell

Acute Myeloid Leukemia ResearchCancer-related Molecular Pathways

Cited by 199

CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors

Negrotto, S., Ng, K. P., Jankowska, A. M., Bodo, J., Gopalan, B., Guinta, K., Mulloy, J. C., Hsi, E., Maciejewski, J., & Saunthararajah, Y. (2012) · Leukemia

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 90

p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia

Ng, K. P., Ebrahem, Q., Negrotto, S., Mahfouz, R. Z., Link, K. A., Hu, Z., Gu, X., Advani, A., Kalaycio, M., Sobecks, R., et al. (2011) · Leukemia

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 68