Curtin, Nicola J.

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

Bryant, H. E., Schultz, N., Thomas, H. D., Parker, K. M., Flower, D., Lopez, E., Kyle, S., Meuth, M., Curtin, N. J., & Helleday, T. (2005) · Nature

PARP inhibition in cancer therapyDNA Repair Mechanisms

Cited by 5,198

Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

Hickson, I., Zhao, Y., Richardson, C. J., Green, S. J., Martin, N. M. B., Orr, A. I., Reaper, P. M., Jackson, S. P., Curtin, N. J., & Smith, G. C. M. (2004) · Cancer Research

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 1,220

DNA repair dysregulation from cancer driver to therapeutic target

Curtin, N. J. (2012) · Nature Reviews Cancer

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 1,051

Anticancer Chemosensitization and Radiosensitization by the Novel Poly(ADP-ribose) Polymerase-1 Inhibitor AG14361

Calabrese, C. R., Almassy, R., Barton, S., Batey, M. A., Calvert, A. H., Canan-Koch, S., Durkacz, B. W., Hostomsky, Z., Kumpf, R. A., Kyle, S., et al. (2004) · JNCI Journal of the National Cancer Institute

PARP inhibition in cancer therapyDNA Repair Mechanisms

Cited by 487

Therapeutic applications of PARP inhibitors: Anticancer therapy and beyond

Curtin, N. J., & Szabo, C. (2013) · Molecular Aspects of Medicine

PARP inhibition in cancer therapyDNA Repair Mechanisms

Cited by 369

PARP inhibitor rucaparib induces changes in NAD levels in cells and liver tissues as assessed by MRS

Almeida, G. S., Bawn, C. M., Galler, M., Wilson, I., Thomas, H. D., Kyle, S., Curtin, N. J., Newell, D. R., & Maxwell, R. J. (2017) · NMR in Biomedicine

PARP inhibition in cancer therapyAdvanced NMR Techniques and Applications

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Differences in Durability of PARP Inhibition by Clinically Approved PARP Inhibitors: Implications for Combinations and Scheduling

Smith, H. L., Willmore, E., Mukhopadhyay, A., Drew, Y., & Curtin, N. J. (2022) · Cancers

PARP inhibition in cancer therapyChronic Lymphocytic Leukemia Research

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