Sprick, Martin R.

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

Vermeulen, L., De Sousa E Melo, F., van der Heijden, M., Cameron, K., de Jong, J. H., Borovski, T., Tuynman, J. B., Todaro, M., Merz, C., Rodermond, H., et al. (2010) · Nature Cell Biology

Cancer Cells and MetastasisWnt/β-catenin signaling in development and cancer

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Survival of pancreatic cancer cells lacking KRAS function

Muzumdar, M. D., Chen, P.-Y., Dorans, K. J., Chung, K. M., Bhutkar, A., Hong, E., Noll, E. M., Sprick, M. R., Trumpp, A., & Jacks, T. (2017) · Nature Communications

Pancreatic and Hepatic Oncology ResearchProtein Kinase Regulation and GTPase Signaling

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Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival

Horn, S., Hughes, M. A., Schilling, R., Sticht, C., Tenev, T., Ploesser, M., Meier, P., Sprick, M. R., MacFarlane, M., & Leverkus, M. (2017) · Cell Reports

Cell death mechanisms and regulationNF-κB Signaling Pathways

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The linear ubiquitin chain assembly complex regulates TRAIL‐induced gene activation and cell death

Lafont, E., Kantari‐Mimoun, C., Draber, P., De Miguel, D., Hartwig, T., Reichert, M., Kupka, S., Shimizu, Y., Taraborrelli, L., Spit, M., et al. (2017) · The EMBO Journal

Cell death mechanisms and regulationNF-κB Signaling Pathways

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Temporal multi-omics identifies LRG1 as a vascular niche instructor of metastasis

Singhal, M., Gengenbacher, N., Abdul Pari, A. A., Kamiyama, M., Hai, L., Kuhn, B. J., Kallenberg, D. M., Kulkarni, S. R., Camilli, C., Preuß, S. F., et al. (2021) · Science Translational Medicine

Angiogenesis and VEGF in CancerCancer Cells and Metastasis

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