Bharadwaj, Uddalak

Targeting Janus Kinases and Signal Transducer and Activator of Transcription 3 To Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and Caution

Bharadwaj, U., Kasembeli, M. M., Robinson, P., & Tweardy, D. J. (2020) · Pharmacological Reviews

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 314

Contribution of STAT3 to inflammatory and fibrotic diseases and prospects for its targeting for treatment

Kasembeli, M. M., Bharadwaj, U., Robinson, P., & Tweardy, D. J. (2018) · International Journal of Molecular Sciences

Cytokine Signaling Pathways and InteractionsPsoriasis: Treatment and Pathogenesis

Cited by 199

Mesothelin confers pancreatic cancer cell resistance to TNF-α-induced apoptosis through Akt/PI3K/NF-κB activation and IL-6/Mcl-1 overexpression

Bharadwaj, U., Marin-Muller, C., Li, M., Chen, C., & Yao, Q. (2011) · Molecular Cancer

Pancreatic and Hepatic Oncology ResearchCell death mechanisms and regulation

Cited by 151

Multifunctional effects of a small-molecule STAT3 inhibitor on NASH and hepatocellular carcinoma in mice

Jung, K. H., Yoo, W., Stevenson, H. L., Deshpande, D., Shen, H., Gagea, M., Yoo, S.-Y., Wang, J., Eckols, T. K., Bharadwaj, U., et al. (2017) · Clinical Cancer Research

Cytokine Signaling Pathways and InteractionsHepatocellular Carcinoma Treatment and Prognosis

Cited by 124

Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferation

Bharadwaj, U., Marin-Muller, C., Li, M., Chen, C., & Yao, Q. (2011) · Carcinogenesis

Cytokine Signaling Pathways and InteractionsPancreatic and Hepatic Oncology Research

Cited by 118

STAT3 inhibition prevents lung inflammation, remodeling, and accumulation of Th2 and Th17 cells in a murine asthma model

Gavino, A. C., Nahmod, K., Bharadwaj, U., Makedonas, G., & Tweardy, D. J. (2016) · Allergy

Asthma and respiratory diseasesCytokine Signaling Pathways and Interactions

Cited by 114

Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer

Lewis, K. M., Bharadwaj, U., Eckols, T. K., Kolosov, M., Kasembeli, M. M., Fridley, C., Siller, R., & Tweardy, D. J. (2015) · Lung Cancer

Cytokine Signaling Pathways and InteractionsLung Cancer Treatments and Mutations

Cited by 63