Yang, Wan Seok

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Dixon, S. J., Lemberg, K. M., Lamprecht, M. R., Skouta, R., Zaitsev, E. M., Gleason, C. E., Patel, D. N., Bauer, A. J., Cantley, A. M., Yang, W. S., et al. (2012) · Cell

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 18,691

Regulation of Ferroptotic Cancer Cell Death by GPX4

Yang, W. S., SriRamaratnam, R., Welsch, M. E., Shimada, K., Skouta, R., Viswanathan, V. S., Cheah, J. H., Clemons, P. A., Shamji, A. F., Clish, C. B., et al. (2014) · Cell

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 7,713

Ferroptosis: Death by Lipid Peroxidation

Yang, W. S., & Stockwell, B. R. (2016) · Trends in Cell Biology

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 3,088

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

Yang, W. S., Kim, K. J., Gaschler, M. M., Patel, M., Shchepinov, M. S., & Stockwell, B. R. (2016) · Proceedings of the National Academy of Sciences

Ferroptosis and cancer prognosisAntioxidant Activity and Oxidative Stress

Cited by 2,329

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Viswanathan, V. S., Ryan, M. J., Dhruv, H. D., Gill, S., Eichhoff, O. M., Seashore-Ludlow, B., Kaffenberger, S. D., Eaton, J. K., Shimada, K., Aguirre, A. J., et al. (2017) · Nature

Ferroptosis and cancer prognosisCancer, Lipids, and Metabolism

Cited by 2,011

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.

Yang, W. S., & Stockwell, B. R. (2008) · Chemistry & Biology

Cell death mechanisms and regulationFerroptosis and cancer prognosis

Cited by 1,876

RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels

Yagoda, N., von Rechenberg, M., Zaganjor, E., Bauer, A. J., Yang, W. S., Fridman, D. J., Wolpaw, A. J., Smukste, I., Peltier, J. M., Boniface, J. J., et al. (2007) · Nature

Cell death mechanisms and regulationProtein Kinase Regulation and GTPase Signaling

Cited by 1,631

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis

Shimada, K., Skouta, R., Kaplan, A., Yang, W. S., Hayano, M., Dixon, S. J., Brown, L. M., Valenzuela, C. A., Wolpaw, A. J., & Stockwell, B. R. (2016) · Nature Chemical Biology

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 1,017

Elucidating Compound Mechanism of Action by Network Perturbation Analysis

Woo, J. H., Shimoni, Y., Yang, W. S., Subramaniam, P., Iyer, A., Nicoletti, P., Rodríguez Martínez, M., López, G., Mattioli, M., Realubit, R., et al. (2015) · Cell

Bioinformatics and Genomic NetworksComputational Drug Discovery Methods

Cited by 351

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

Weïwer, M., Bittker, J. A., Lewis, T. A., Shimada, K., Yang, W. S., MacPherson, L., Dandapani, S., Palmer, M., Stockwell, B. R., Schreiber, S. L., et al. (2012) · Bioorganic & Medicinal Chemistry Letters

Protein Kinase Regulation and GTPase SignalingProtein Tyrosine Phosphatases

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