Christoffolete, Marcelo A.

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Watanabe, M., Houten, S. M., Mataki, C., Christoffolete, M. A., Kim, B. W., Sato, H., Messaddeq, N., Harney, J. W., Ezaki, O., Kodama, T., et al. (2006) · Nature

Adipose Tissue and MetabolismDrug Transport and Resistance Mechanisms

Cited by 2,220

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

Dentice, M., Bandyopadhyay, A., Gereben, B., Callebaut, I., Christoffolete, M. A., Kim, B. W., Nissim, S., Mornon, J.-P., Zavacki, A. M., Zeöld, A., et al. (2005) · Nature Cell Biology

Hedgehog Signaling Pathway StudiesUbiquitin and proteasome pathways

Cited by 227

Mice with Targeted Disruption of the Dio2 Gene Have Cold-Induced Overexpression of the Uncoupling Protein 1 Gene but Fail to Increase Brown Adipose Tissue Lipogenesis and Adaptive Thermogenesis

Christoffolete, M. A., Linardi, C. C. G., de Jesus, L., Ebina, K. N., Carvalho, S. D., Ribeiro, M. O., Rabelo, R., Curcio, C., Martins, L., Kimura, E. T., et al. (2004) · Diabetes

Adipose Tissue and MetabolismLipid metabolism and biosynthesis

Cited by 212

Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse

Zavacki, A. M., Ying, H., Christoffolete, M. A., Aerts, G., So, E., Harney, J. W., Cheng, S.-Y., Larsen, P. R., & Bianco, A. C. (2005) · Endocrinology

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 138

Atypical Expression of Type 2 Iodothyronine Deiodinase in Thyrotrophs Explains the Thyroxine-Mediated Pituitary Thyrotropin Feedback Mechanism

Christoffolete, M. A., Ribeiro, R., Singru, P., Fekete, C., da Silva, W. S., Gordon, D. F., Huang, S. A., Crescenzi, A., Harney, J. W., Ridgway, E. C., et al. (2006) · Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 118

Differential effects of central leptin, insulin, or glucose administration during fasting on the hypothalamic-pituitary-thyroid axis and feeding-related neurons in the arcuate nucleus

Fekete, C., Singru, P. S., Sanchez, E., Sarkar, S., Christoffolete, M. A., Riberio, R. S., Rand, W. M., Emerson, C. H., Bianco, A. C., & Lechan, R. M. (2006) · Endocrinology

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 97

Mice with Impaired Extrathyroidal Thyroxine to 3,5,3′-Triiodothyronine Conversion Maintain Normal Serum 3,5,3′-Triiodothyronine Concentrations

Christoffolete, M. A., Arrojo e Drigo, R., Gazoni, F., Tente, S. M., Goncalves, V., Amorim, B. S., Larsen, P. R., Bianco, A. C., & Zavacki, A. M. (2007) · Endocrinology

Thyroid Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors

Cited by 62

Bacterial lipopolysaccharide (LPS)-induced type 2 iodothyronine deiodinase (D2) activation in the mediobasal hypothalamus (MBH) is independent of the LPS-induced fall in serum thyroid hormone levels

Fekete, C., Sarkar, S., Christoffolete, M. A., Emerson, C. H., Bianco, A. C., & Lechan, R. M. (2005) · Brain Research

Thyroid Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 54

Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of type 2 deiodinase in the rat brain

Fekete, C., Freitas, B. C. G., Zeöld, A., Wittmann, G., Kádár, A., Liposits, Z., Christoffolete, M. A., Singru, P., Lechan, R. M., Bianco, A. C., et al. (2007) · Endocrinology

Thyroid Disorders and TreatmentsUbiquitin and proteasome pathways

Cited by 33

A low-protein, high-carbohydrate diet increases browning in perirenal adipose tissue but not in inguinal adipose tissue

Pereira, M. P., Ferreira, L. A. A., da Silva, F. H. S., Christoffolete, M. A., Metsios, G. S., Chaves, V. E., de França, S. A., Damazo, A. S., Flouris, A. D., & Kawashita, N. H. (2017) · Nutrition

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 24