Keefe, Anthony D.

Aptamers as therapeutics

Keefe, A. D., Pai, S., & Ellington, A. (2010) · Nature Reviews Drug Discovery

Advanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery

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DNA-encoded chemistry: enabling the deeper sampling of chemical space

Goodnow, R. A., Dumelin, C. E., & Keefe, A. D. (2017) · Nature Reviews Drug Discovery

Chemical Synthesis and AnalysisComputational Drug Discovery Methods

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Novel irreversible covalent BTK inhibitors discovered using DNA-encoded chemistry

Guilinger, J. P., Archna, A., Augustin, M., Bergmann, A., Centrella, P. A., Clark, M. A., Cuozzo, J. W., Däther, M., Guié, M.-A., Habeshian, S., et al. (2021) · Bioorganic & Medicinal Chemistry

Chemical Synthesis and AnalysisClick Chemistry and Applications

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A resource to enable chemical biology and drug discovery of WDR Proteins

Ackloo, S., Li, F., Szewczyk, M., Seitova, A., Loppnau, P., Zeng, H., Xu, J., Ahmad, S., Arnautova, Y. A., Baghaie, A., et al. (2024) · Journal of Medicinal Chemistry

Computational Drug Discovery MethodsProtein Degradation and Inhibitors

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