Saunders, Ann M.

Safety and efficacy of pioglitazone for the delay of cognitive impairment in people at risk of Alzheimer’s disease (TOMMORROW): a prognostic biomarker study and a phase 3, randomised, double-blind, placebo-controlled trial.

Burns, D. K., Alexander, R. C., Welsh-Bohmer, K. A., Culp, M., Chiang, C., O’Neil, J., Evans, R. M., Harrigan, P., Plassman, B. L., Burke, J. R., et al. (2021) · The Lancet Neurology

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The effect of TOMM40 poly‐T length on gray matter volume and cognition in middle‐aged persons with APOEɛ 3/ɛ 3 genotype

Johnson, S. C., La Rue, A., Hermann, B. P., Xu, G., Koscik, R. L., Jonaitis, E. M., Bendlin, B. B., Hogan, K. J., Roses, A. D., Saunders, A. M., et al. (2011) · Alzheimer's & Dementia

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APOE is a major susceptibility gene for Alzheimer’s disease

Roses, A. D., & Saunders, A. M. (1994) · Current Opinion in Biotechnology

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Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons

Brodbeck, J., Balestra, M. E., Saunders, A. M., Roses, A. D., Mahley, R. W., & Huang, Y. (2008) · Proceedings of the National Academy of Sciences

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Apolipoprotein E is associated with age at onset of amyotrophic lateral sclerosis

Li, Y.-J., Pericak-Vance, M. A., Haines, J. L., Siddique, N., McKenna-Yasek, D., Hung, W.-Y., Sapp, P., Allen, C. I., Chen, W., Hosler, B., et al. (2004) · Neurogenetics

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Understanding the genetics of APOE and TOMM40 and role of mitochondrial structure and function in clinical pharmacology of Alzheimer's disease

Roses, A., Sundseth, S., Saunders, A., Gottschalk, W., Burns, D., & Lutz, M. (2016) · Alzheimer's & Dementia

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Using genetics to enable studies on the prevention of Alzheimer's disease

Crenshaw, D. G., Gottschalk, W. K., Lutz, M. W., Grossman, I., Saunders, A. M., Burke, J. R., Welsh-Bohmer, K. A., Brannan, S. K., Burns, D. K., & Roses, A. D. (2013) · Clinical Pharmacology & Therapeutics

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Longitudinal modeling of cognitive aging and the TOMM40 effect

Caselli, R. J., Dueck, A. C., Huentelman, M. J., Lutz, M. W., Saunders, A. M., Reiman, E. M., & Roses, A. D. (2012) · Alzheimer's & Dementia

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TOMM40 and APOE: Requirements for replication studies of association with age of disease onset and enrichment of a clinical trial

Roses, A. D., Lutz, M. W., Crenshaw, D. G., Grossman, I., Saunders, A. M., & Gottschalk, W. K. (2013) · Alzheimer's & Dementia

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A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging

Hayden, K. M., McEvoy, J. M., Linnertz, C., Attix, D., Kuchibhatla, M., Saunders, A. M., Lutz, M. W., Welsh‐Bohmer, K. A., Roses, A. D., & Chiba‐Falek, O. (2012) · Alzheimer's & Dementia

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Alzheimer’s disease: diagnostics, prognostics and the road to prevention

Grossman, I., Lutz, M. W., Crenshaw, D. G., Saunders, A. M., Burns, D. K., & Roses, A. D. (2010) · EPMA Journal

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A genetics-based biomarker risk algorithm for predicting risk of Alzheimer's disease

Lutz, M. W., Sundseth, S. S., Burns, D. K., Saunders, A. M., Hayden, K. M., Burke, J. R., Welsh‐Bohmer, K. A., Roses, A. D., & Initiative, A. D. N. (2016) · Alzheimer's & Dementia: Translational Research & Clinical Interventions

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