Friedman, Alan D.

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

Umek, R. M., Friedman, A. D., & McKnight, S. L. (1991) · Science

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 712

Transcriptional control of granulocyte and monocyte development

Friedman, A. D. (2007) · Oncogene

Hematopoietic Stem Cell TransplantationGenomics and Chromatin Dynamics

Cited by 427

C/EBP, c-Myb, and PU.1 Cooperate To Regulate the Neutrophil Elastase Promoter

Oelgeschläger, M., Nuchprayoon, I., Lüscher, B., & Friedman, A. D. (1996) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 229

Multiple Functional Domains of AML1: PU.1 and C/EBPα Synergize with Different Regions of AML1

Petrovick, M. S., Hiebert, S. W., Friedman, A. D., Hetherington, C. J., Tenen, D. G., & Zhang, D.-E. (1998) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 218

C/EBP Bypasses Granulocyte Colony-Stimulating Factor Signals to Rapidly Induce PU.1 Gene Expression, Stimulate Granulocytic Differentiation, and Limit Proliferation in 32D cl3 Myeloblasts

Wang, X., Scott, E., Sawyers, C. L., & Friedman, A. D. (1999) · Blood

Retinoids in leukemia and cellular processesAcute Myeloid Leukemia Research

Cited by 166

Identification of two polypeptide segments of CCAAT/enhancer-binding protein required for transcriptional activation of the serum albumin gene.

Friedman, A. D., & McKnight, S. L. (1990) · Genes & Development

Genomics and Chromatin DynamicsCytokine Signaling Pathways and Interactions

Cited by 162

The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain

Durst, K. L., Lutterbach, B., Kummalue, T., Friedman, A. D., & Hiebert, S. W. (2003) · Molecular and Cellular Biology

Acute Myeloid Leukemia ResearchGenomics and Chromatin Dynamics

Cited by 161

C/EBPα binds and activates the PU.1 distal enhancer to induce monocyte lineage commitment

Yeamans, C., Wang, D., Paz-Priel, I., Torbett, B. E., Tenen, D. G., & Friedman, A. D. (2007) · Blood

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 118

C/EBPα:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBPα homodimers or AP-1

Cai, D. H., Wang, D., Keefer, J., Yeamans, C., Hensley, K., & Friedman, A. D. (2008) · Oncogene

Genomics and Chromatin DynamicsCytokine Signaling Pathways and Interactions

Cited by 96

C/EBPα determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation

Suh, H. C., Gooya, J., Renn, K., Friedman, A. D., Johnson, P. F., & Keller, J. R. (2006) · Blood

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 95

Core Binding Factor Cannot Synergistically Activate the Myeloperoxidase Proximal Enhancer in Immature Myeloid Cells without c-Myb

Britos-Bray, M., & Friedman, A. D. (1997) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 94

The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1).

Suzow, J., & Friedman, A. D. (1993) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 93

Cross-talk between regulators of myeloid development: C/EBPα binds and activates the promoter of the PU.1 gene

Kummalue, T., & Friedman, A. D. (2003) · Journal of Leukocyte Biology

Genomics and Chromatin DynamicsRetinoids in leukemia and cellular processes

Cited by 52

Identification of Transcriptional Activation and Repression Domains in Human CCAAT/Enhancer-binding Protein ε

Williamson, E. A., Xu, H. N., Gombart, A. F., Verbeek, W., Chumakov, A. M., Friedman, A. D., & Koeffler, H. P. (1998) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsCytokine Signaling Pathways and Interactions

Cited by 50