C/EBPα:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBPα homodimers or AP-1
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C/EBP-α directly activates transcription of PU.1 in monocytes.
“It has previously been shown that C/EBP-α directly activates transcription of PU.1 in monocytes30”
From MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway (2011) · cites this paper as [30]
C/EBP-α binds the promoter region of PU.1 and induces its transcription.
“As C/EBP-α binds the promoter region of PU.1 and induces its transcription30,31”
From MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway (2011) · cites this paper as [30]
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Cites
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Research works printed but not linked: 19
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The transcription factor PU.1 is critical for viability and function of human brain microglia
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Manea, A., Manea, S. A., Florea, I. C., Luca, C. M., & Raicu, M. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.02.018 · Cited by 52 · see citing works
- Authors
- Cai, D. H., Wang, D., Keefer, J., Yeamans, C., Hensley, K., & Friedman, A. D.
- Venue
- Oncogene
- Published
- 2007-11-19
- Volume
- 27
- Issue
- 19
- Pages
- 2772-2779
- ISSN
- 0950-9232
- 1476-5594
- Cited by
- 86
- References
- 1
- Language
- en
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