Lappin, Terence R. J.

A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis

Percy, M. J., Zhao, Q., Flores, A., Harrison, C., Lappin, T. R. J., Maxwell, P. H., McMullin, M. F., & Lee, F. S. (2006) · Proceedings of the National Academy of Sciences

Erythropoietin and Anemia TreatmentCancer, Hypoxia, and Metabolism

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A Gain-of-Function Mutation in the HIF2A Gene in Familial Erythrocytosis

Percy, M. J., Furlow, P. W., Lucas, G. S., Li, X., Lappin, T. R. J., McMullin, M. F., & Lee, F. S. (2008) · New England Journal of Medicine

Erythropoietin and Anemia TreatmentCancer, Hypoxia, and Metabolism

Cited by 314

Mutation of von Hippel–Lindau Tumour Suppressor and Human Cardiopulmonary Physiology

Smith, T. G., Brooks, J. T., Balanos, G. M., Lappin, T. R., Layton, D. M., Leedham, D. L., Liu, C., Maxwell, P. H., McMullin, M. F., McNamara, C. J., et al. (2006) · PLoS Medicine

High Altitude and HypoxiaPulmonary Hypertension Research and Treatments

Cited by 182

A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove

Percy, M. J., Furlow, P. W., Beer, P. A., Lappin, T. R. J., McMullin, M. F., & Lee, F. S. (2007) · Blood

Erythropoietin and Anemia TreatmentCancer, Hypoxia, and Metabolism

Cited by 155

Novel exon 12 mutations in the HIF2A gene associated with erythrocytosis

Percy, M. J., Beer, P. A., Campbell, G., Dekker, A. W., Green, A. R., Oscier, D., Rainey, M. G., van Wijk, R., Wood, M., Lappin, T. R. J., et al. (2008) · Blood

Erythropoietin and Anemia TreatmentCancer, Hypoxia, and Metabolism

Cited by 127

Cardiopulmonary function in two human disorders of the hypoxia‐inducible factor (HIF) pathway: von Hippel‐Lindau disease and HIF‐2α gain‐of‐function mutation

Formenti, F., Beer, P. A., Croft, Q. P. P., Dorrington, K. L., Gale, D. P., Lappin, T. R. J., Lucas, G. S., Maher, E. R., Maxwell, P. H., McMullin, M. F., et al. (2011) · The FASEB Journal

Cancer, Hypoxia, and MetabolismPulmonary Hypertension Research and Treatments

Cited by 92

Chuvash-type congenital polycythemia in 4 families of Asian and Western European ancestry

Percy, M. J., McMullin, M. F., Jowitt, S. N., Potter, M., Treacy, M., Watson, W. H., & Lappin, T. R. J. (2003) · Blood

Erythropoietin and Anemia TreatmentMyeloproliferative Neoplasms: Diagnosis and Treatment

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Erythrocytosis-associated HIF-2α Mutations Demonstrate a Critical Role for Residues C-terminal to the Hydroxylacceptor Proline

Furlow, P. W., Percy, M. J., Sutherland, S., Bierl, C., McMullin, M. F., Master, S. R., Lappin, T. R. J., & Lee, F. S. (2009) · Journal of Biological Chemistry

Erythropoietin and Anemia TreatmentCancer, Hypoxia, and Metabolism

Cited by 58

Wnt–β-catenin–Tcf-4 signalling-modulated invasiveness is dependent on osteopontin expression in breast cancer

Ravindranath, A., Yuen, H.-F., Chan, K.-K., Grills, C., Fennell, D. A., Lappin, T. R., & El-Tanani, M. (2011) · British Journal of Cancer

Wnt/β-catenin signaling in development and cancerBone and Dental Protein Studies

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Two new mutations in the HIF2A gene associated with erythrocytosis

Percy, M. J., Chung, Y. J., Harrison, C., Mercieca, J., Hoffbrand, A. V., Dinardo, C. L., Santos, P. C. J. L., Fonseca, G. H. H., Gualandro, S. F. M., Pereira, A. C., et al. (2012) · American Journal of Hematology

Erythropoietin and Anemia TreatmentCancer, Hypoxia, and Metabolism

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A randomized trial investigating an iron-rich natural mineral water as a prophylaxis against iron deficiency in pregnancy: Iron deficiency and its prophylaxis in pregnancy

McKenna, D., Spence, D., Haggan, S. E., McCrum, E., Dornan, J. C., & Lappin, T. R. (2003) · Clinical & Laboratory Haematology

Iron Metabolism and DisordersTrace Elements in Health

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