Franklin, Matthew C.

Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail

Hansen, J., Baum, A., Pascal, K. E., Russo, V., Giordano, S., Wloga, E., Fulton, B. O., Yan, Y., Koon, K., Patel, K., et al. (2020) · Science

SARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 1,210

Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

Flygare, J. A., Beresini, M., Budha, N., Chan, H., Chan, I. T., Cheeti, S., Cohen, F., Deshayes, K., Doerner, K., Eckhardt, S. G., et al. (2012) · Journal of Medicinal Chemistry

Cell death mechanisms and regulationHeterocyclic Compound Synthesis and Bioactivity

Cited by 252

Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement

Orengo, J. M., Radin, A. R., Kamat, V., Badithe, A., Ben, L. H., Bennett, B. L., Zhong, S., Birchard, D., Limnander, A., Rafique, A., et al. (2018) · Nature Communications

Allergic Rhinitis and SensitizationFood Allergy and Anaphylaxis Research

Cited by 237

The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies

Copin, R., Baum, A., Wloga, E., Pascal, K. E., Giordano, S., Fulton, B. O., Zhou, A., Negron, N., Lanza, K., Chan, N., et al. (2021) · Cell

SARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 212

Structural insights into the assembly of gp130 family cytokine signaling complexes

Zhou, Y., Stevis, P. E., Cao, J., Saotome, K., Wu, J., Glatman Zaretsky, A., Haxhinasto, S., Yancopoulos, G. D., Murphy, A. J., Sleeman, M. W., et al. (2023) · Science Advances

Cytokine Signaling Pathways and InteractionsReceptor Mechanisms and Signaling

Cited by 56

CryoEM structure of ALK2:BMP6 reveals distinct mechanisms that allow ALK2 to interact with both BMP and Activin ligands

Goebel, E. J., Aykul, S., Saotome, K., Economides, A. N., Franklin, M. C., & Idone, V. J. (2025) · Proceedings of the National Academy of Sciences

TGF-β signaling in diseasesReceptor Mechanisms and Signaling

Cited by 2

CryoEM structure of ALK2:BMP6 reveals distinct mechanism that allow ALK2 to interact with both BMP and activin ligands

Goebel, E. J., Aykul, S., Hom, W. W., Saotome, K., Economides, A. N., Franklin, M. C., & Idone, V. J. (2025) · Proceedings of the National Academy of Sciences

TGF-β signaling in diseasesReceptor Mechanisms and Signaling

Cited by 2